Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Michael P Guy"'
Autor:
Holly M Funk, Ruoxia Zhao, Maggie Thomas, Sarah M Spigelmyer, Nichlas J Sebree, Regan O Bales, Jamison B Burchett, Justen B Mamaril, Patrick A Limbach, Michael P Guy
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242737 (2020)
Posttranscriptional modification of tRNA is critical for efficient protein translation and proper cell growth, and defects in tRNA modifications are often associated with human disease. Although most of the enzymes required for eukaryotic tRNA modifi
Externí odkaz:
https://doaj.org/article/e7f239aef046469c8bc28f0291c60ace
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007288 (2018)
Modification defects in the tRNA anticodon loop often impair yeast growth and cause human disease. In the budding yeast Saccharomyces cerevisiae and the phylogenetically distant fission yeast Schizosaccharomyces pombe, trm7Δ mutants grow poorly due
Externí odkaz:
https://doaj.org/article/1349249538fa4ac9b33b92c50bba4d6c
Publikováno v:
ACS Omega, Vol 9, Iss 23, Pp 25063-25072 (2024)
Externí odkaz:
https://doaj.org/article/dfc0384feade4fee8b77fa41b2f27afd
Autor:
Holly M. Funk, Daisy J. DiVita, Hannah E. Sizemore, Kendal Wehrle, Catherine L. W. Miller, Morgan E. Fraley, Alex K. Mullins, Adrian R. Guy, Eric M. Phizicky, Michael P. Guy
Publikováno v:
ACS Omega. 7:13667-13675
Autor:
Michael J. Jarrett, Andres Vázquez-Torres, Daniel N. Frank, Bruce D. McCollister, Patrick K. Henthorn, Diana Ir, Jeanelle Sheeder, Michael S. Guy, Hiba Q. Anwar, Kian Behbakht
Publikováno v:
Infectious Diseases in Obstetrics and Gynecology, Vol 2016 (2016)
Objective. Gelatin-thrombin matrix (GTM) tissue sealant use was previously identified as an independent predictor of pelvic infection following hysterectomies. We aim to elucidate contributing factors by assessing influence of GTM on bacterial colony
Externí odkaz:
https://doaj.org/article/b4bf56ffc8dc4cba968c27099564ff64
Autor:
Holly M, Funk, Daisy J, DiVita, Hannah E, Sizemore, Kendal, Wehrle, Catherine L W, Miller, Morgan E, Fraley, Alex K, Mullins, Adrian R, Guy, Eric M, Phizicky, Michael P, Guy
Publikováno v:
ACS omega. 7(16)
Posttranscriptional tRNA modifications are essential for proper gene expression, and defects in the enzymes that perform tRNA modifications are associated with numerous human disorders. Throughout eukaryotes, 2'
Identification of a motif in Trm732 required for 2’-O-methylation of the tRNA anticodon loop by Trm7
Autor:
Catherine L. Weiner, Michael P. Guy, Eric M. Phizicky, Funk Hm, Guy Ar, Sizemore He, Wehrle K, DiVita Dj
Posttranscriptional tRNA modifications are essential for proper gene expression, and defects in the enzymes that perform tRNA modifications are associated with numerous human disorders. Throughout eukaryotes, 2’-O-methylation of residues 32 and 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc6a4e46173362da34f95228bdd019d9
https://doi.org/10.1101/2021.06.03.446962
https://doi.org/10.1101/2021.06.03.446962
Autor:
Yoshiko Kon, Stanley Fields, David H. Mathews, Xiaoju Zhang, Eric M. Phizicky, Michael P. Guy, Thareendra De Zoysa, Michael F. Sloma, Matthew J. Payea, David L. Young
Microorganisms have universally adapted their RNAs and proteins to survive at a broad range of temperatures and growth conditions. However, for RNAs, there is little quantitative understanding of the effects of mutations on function at high temperatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3384d53cec52dc6ea9e795aef15d0964
https://europepmc.org/articles/PMC5824359/
https://europepmc.org/articles/PMC5824359/
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 3, p e1007288 (2018)
PLoS Genetics, Vol 14, Iss 3, p e1007288 (2018)
Modification defects in the tRNA anticodon loop often impair yeast growth and cause human disease. In the budding yeast Saccharomyces cerevisiae and the phylogenetically distant fission yeast Schizosaccharomyces pombe, trm7Δ mutants grow poorly due
Autor:
Michael P. Guy, Eric M. Phizicky
Publikováno v:
RNA Biology
tRNA modifications are crucial for efficient and accurate protein translation, with defects often linked to disease. There are 7 cytoplasmic tRNA modifications in the yeast Saccharomyces cerevisiae that are formed by an enzyme consisting of a catalyt