Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Michael P Fay"'
Autor:
Michael P Fay, Loretta G Que, A Parker Ruhl, Jarrett M Jackson, Carlos J Carhuas, Jessica G Niño de Rivera, J Brice Weinberg, Hans C Ackerman
Publikováno v:
BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Introduction The genetic determinants of fractional exhalation of nitric oxide (FeNO), a marker of lung inflammation, are understudied in Black individuals. Alpha globin (HBA) restricts nitric oxide signalling in arterial endothelial cells via intera
Externí odkaz:
https://doaj.org/article/8c05ecbd115f487b933fa161e0acf5e1
Autor:
Nancy A Niemuth, Dawn Fallacara, Cheryl A Triplett, Sanjay M Tamrakar, Alisha Rajbhandari, Clint Florence, Lucy Ward, Anthony Griffiths, Ricardo Carrion, Yenny Goez-Gazi, Kendra J Alfson, Hilary M Staples, Trevor Brasel, Jason E Comer, Shane Massey, Jeanon Smith, Andrew Kocsis, Jake Lowry, Sara C Johnston, Aysegul Nalca, Arthur J Goff, Amy C Shurtleff, Margaret L Pitt, John Trefry, Michael P Fay
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0252874 (2021)
Filoviruses (Family Filoviridae genera Ebolavirus and Marburgvirus) are negative-stranded RNA viruses that cause severe health effects in humans and non-human primates, including death. Except in outbreak settings, vaccines and other medical counterm
Externí odkaz:
https://doaj.org/article/872942b1dcae494498eca02d622ed9e7
Autor:
Kawsar R Talaat, Ruth D Ellis, Janet Hurd, Autumn Hentrich, Erin Gabriel, Noreen A Hynes, Kelly M Rausch, Daming Zhu, Olga Muratova, Raul Herrera, Charles Anderson, David Jones, Joan Aebig, Sarah Brockley, Nicholas J MacDonald, Xiaowei Wang, Michael P Fay, Sara A Healy, Anna P Durbin, David L Narum, Yimin Wu, Patrick E Duffy
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163144 (2016)
Transmission-blocking vaccines (TBVs) that target sexual stage parasite development could be an integral part of measures for malaria elimination. Pfs25 is a leading TBV candidate, and previous studies conducted in animals demonstrated an improvement
Externí odkaz:
https://doaj.org/article/93a3af0304db4dbb8a1f1800b018de1b
Autor:
Kawsar R Talaat, Subash Babu, Pradeep Menon, N Kumarasamy, Jabin Sharma, Jeeva Arumugam, Kalaivani Dhakshinamurthy, Ramalingam Srinivasan, S Poongulali, Wenjuan Gu, Michael P Fay, Soumya Swaminathan, Thomas B Nutman
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003622 (2015)
BACKGROUND:The disease course of human immunodeficiency virus (HIV) is often altered by existing or newly acquired coincident infections. METHODOLOGY/PRINCIPAL FINDINGS:To assess the influence of pre-existing Wuchereria bancrofti infection on HIV pro
Externí odkaz:
https://doaj.org/article/93d12b3d396e4b6fb67cfa1d33d2ad97
Autor:
Soumya Chatterjee, Chockalingam Kolappan, Rangasamy Subramani, Punnathanathu G Gopi, Vedhachalam Chandrasekaran, Michael P Fay, Subash Babu, Vasanthapuram Kumaraswami, Thomas B Nutman
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94603 (2014)
Filarial (and other helminth) infections are known to modulate mycobacteria-specific pro-inflammatory cytokine responses necessary for maintaining latency in tuberculosis (TB). We sought to address whether helminth co-infection alters progression to
Externí odkaz:
https://doaj.org/article/ade17bad966b46d3a936da29eae0788c
Autor:
Jeanette T Beaudry, Michael A Krause, Seidina A S Diakite, Michael P Fay, Gyan Joshi, Mahamadou Diakite, Nicholas J White, Rick M Fairhurst
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92185 (2014)
Sickle hemoglobin (Hb) S and HbC may protect against malaria by reducing the expression of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) on the surface of parasitized red blood cells (RBCs), thereby weakening their cytoadherence to mi
Externí odkaz:
https://doaj.org/article/20460acf91434ee5ae331af77a77e62a
Autor:
Markus Ruhsam, Maarten J. M. Christenhusz, Ilia J. Leitch, Michael F. Fay, Peter M Hollingsworth, Katie E. Herron, Ann M. Mc Cartney, Graham M. Hughes
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
We present a genome assembly from an individual Trifolium dubium (lesser trefoil; Tracheophyta; Magnoliopsida; Fabales; Fabaceae) as part of a collaboration between the Darwin Tree of Life and the European Reference Genome Atlas. The genome sequence
Externí odkaz:
https://doaj.org/article/2575e441f7ba48e3ad04af8923c8e136
A potential role for plasma uric acid in the endothelial pathology of Plasmodium falciparum malaria.
Autor:
Neida K Mita-Mendoza, Diana L van de Hoef, Tatiana M Lopera-Mesa, Saibou Doumbia, Drissa Konate, Mory Doumbouya, Wenjuan Gu, Jennifer M Anderson, Leopoldo Santos-Argumedo, Ana Rodriguez, Michael P Fay, Mahamadou Diakite, Carole A Long, Rick M Fairhurst
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54481 (2013)
Inflammatory cytokinemia and systemic activation of the microvascular endothelium are central to the pathogenesis of Plasmodium falciparum malaria. Recently, 'parasite-derived' uric acid (UA) was shown to activate human immune cells in vitro, and pla
Externí odkaz:
https://doaj.org/article/3b9248e667494ba4a97dd8e59cc3332c
Autor:
Kazutoyo Miura, Bingbing Deng, Gregory Tullo, Ababacar Diouf, Samuel E Moretz, Emily Locke, Merribeth Morin, Michael P Fay, Carole A Long
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57909 (2013)
Vaccines that interrupt malaria transmission are of increasing interest and a robust functional assay to measure this activity would promote their development by providing a biologically relevant means of evaluating potential vaccine candidates. Ther
Externí odkaz:
https://doaj.org/article/17dd1cc19b684a4bb25e0d9d87fb7b5c
Autor:
R Anuradha, P Jovvian George, N Pavan Kumar, Michael P Fay, V Kumaraswami, Thomas B Nutman, Subash Babu
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002749 (2012)
Lymphatic filariasis can be associated with development of serious pathology in the form of lymphedema, hydrocele, and elephantiasis in a subset of infected patients. Dysregulated host inflammatory responses leading to systemic immune activation are
Externí odkaz:
https://doaj.org/article/4d557dea9b5f465787badb5ccac16902