Zobrazeno 1 - 10
of 282
pro vyhledávání: '"Michael P Brenner"'
Autor:
Garrett Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, Vivian P. Bykerk, Laura T. Donlin, Susan M. Goodman, Gary S. Firestein, David L. Boyle, V. Michael Holers, Larry W. Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B. Brenner, Juilee Thakar, Andrew McDavid, Deepak A. Rao, Jennifer H. Anolik
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Rheumatoid arthritis (RA) is an autoimmune disease involving antigen-specific T and B cells. Here, we perform single-cell RNA and repertoire sequencing on paired synovial tissue and blood samples from 12 seropositive RA patients. We identify
Externí odkaz:
https://doaj.org/article/b76b85a9921847d4919133eeb47ed023
Autor:
Arianna Di Stadio, Massimo Ralli, Pietro De Luca, Jake Sossamon, Teresa C. Frohman, Marta Altieri, Ignazio La Mantia, Salvatore Ferlito, Elliot M. Frohman, Michael J. Brenner
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundFacial synkinesis (FS) is a distressing sequela of facial palsy (FP) characterized by involuntary, simultaneous movements of facial muscles occurring during voluntary facial expressions. Treatment of synkinesis is challenging, and preventiv
Externí odkaz:
https://doaj.org/article/c6920ae421d54453bd6aa4d0fa5f017c
Autor:
Kathryn Weinand, Saori Sakaue, Aparna Nathan, Anna Helena Jonsson, Fan Zhang, Gerald F. M. Watts, Majd Al Suqri, Zhu Zhu, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, Deepak A. Rao, Jennifer H. Anolik, Michael B. Brenner, Laura T. Donlin, Kevin Wei, Soumya Raychaudhuri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Synovial tissue inflammation is a hallmark of rheumatoid arthritis (RA). Recent work has identified prominent pathogenic cell states in inflamed RA synovial tissue, such as T peripheral helper cells; however, the epigenetic regulation of the
Externí odkaz:
https://doaj.org/article/6fa32e092ab54daeaadb71dbcca5722d
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 9, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/2ca4d62735304ed294489daa7844e2f6
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The self-assembly of complex structures from a set of non-identical building blocks is a hallmark of soft matter and biological systems, including protein complexes, colloidal clusters, and DNA-based assemblies. Predicting the dependence of
Externí odkaz:
https://doaj.org/article/f826bb9284c04ea48e5af07eb70c0811
Autor:
Richard Furie, Judith A James, Maria Dall’Era, Michelle A Petri, Chaim Putterman, Peter Izmirly, Jill P Buyon, Diane L Kamen, Betty Diamond, David Wofsy, Soumya Raychaudhuri, Jennifer Grossman, Fan Zhang, Jun Inamo, Nir Hacohen, Alice Horisberger, Kenneth C Kalunian, Michael B Brenner, Mariko Ishimori, David Hildeman, Robert Clancy, ANNE DAVIDSON, Matthias Kretzler, Michael Weisman, Celine C Berthier, Andrea Fava, Takanori Sasaki, Jennifer L Barnas, Jennifer H Anolik, Paul J Hoover, Deepak A Rao, Joshua Keegan, James A Lederer, Joel Guthridge, Michael Belmont, Arnon Arazi, William Apruzzese, Fernanda Payan-Schober, Jeffrey Hodgin, Thomas M Eisenhaure, Steve Woodle, Maureen A McMahon, Ekaterina Murzin, Katie Preisinger, Alec Griffith, Kaitlyn Howard, Tusharkanti Ghosh, Rebecca Beuschel, John Pulford, Brandon Hancock, Maria Gutierrez-Arcelus
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/af7a6997976c427eb75e9753159ca89f
Autor:
Richard Furie, Joel M Guthridge, Judith A James, Maria Dall’Era, Michelle A Petri, Chaim Putterman, Jill P Buyon, Diane L Kamen, Betty Diamond, David Wofsy, Soumya Raychaudhuri, Thomas Tuschl, Jennifer Grossman, Peter M Izmirly, Qian Xiao, Nir Hacohen, Kenneth C Kalunian, Michael B Brenner, Mariko Ishimori, H Michael Belmont, Robert Clancy, ANNE DAVIDSON, Matthias Kretzler, Michael Weisman, Celine C Berthier, Andrea Fava, Jennifer L Barnas, Jennifer H Anolik, Paul J Hoover, Deepak A Rao, Arnon Arazi, William Apruzzese, Fernanda Payan-Schober, Joseph Mears, Saori Sakaue, James Lederer, Michael Peters, Tony Jones, Thomas M Eisenhaure, Siddarth Gurajala, Derek Fine, David A Hildeman, Steve Woodle, Maureen A McMahon, Jeffery Hodgin
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/65b7bcfbd80b4d188bbcb8ba5050d6cc
Autor:
Franklin M. Wu, Daniel Gorelik, Michael J. Brenner, Masayoshi Takashima, Amit Goyal, Ashley E. Kita, Austin S. Rose, Robert S. Hong, Waleed M. Abuzeid, Peter Santa Maria, Ahmed A. Al‐Sayed, Michael E. Dunham, Prajoy Kadkade, Scott R. Schaffer, Alan W. Johnson, Adrien A. Eshraghi, Shireen Samargandy, Robert J. Morrison, Philip A. Weissbrod, Margaret B. Mitchell, Cyrus C. Rabbani, Neil Futran, Omar G. Ahmed
Publikováno v:
OTO Open, Vol 8, Iss 1, Pp n/a-n/a (2024)
Abstract Objective To review new drugs and devices relevant to otolaryngology approved by the Food and Drug Administration (FDA) in 2022. Data Sources Publicly available FDA data on drugs and devices approved in 2022. Review Methods A preliminary scr
Externí odkaz:
https://doaj.org/article/de80a9a3268347119103da77748f3807
Autor:
Vinciya Pandian, Michael J. Brenner
Publikováno v:
Revista de Enfermagem Referência, Vol 6, Iss 2 (2023)
Externí odkaz:
https://doaj.org/article/8b358672e9114b0bb40114faf5968da8
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
RNA molecules aggregate in certain conditions, but how and why remains unclear. Here the authors develop a model that quantitatively explains the conditions and mechanism of RNA aggregation, and predicts a surprising non-monotonicity in the transitio
Externí odkaz:
https://doaj.org/article/eedc5c21c2c44e18b269683448b172ab