Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Michael P, Snyder"'
Autor:
Mahdi Moqri, Andrea Cipriano, Daniel J. Simpson, Sajede Rasouli, Tara Murty, Tineke Anna de Jong, Daniel Nachun, Guilherme de Sena Brandine, Kejun Ying, Andrei Tarkhov, Karolina A. Aberg, Edwin van den Oord, Wanding Zhou, Andrew Smith, Crystal Mackall, Vadim N. Gladyshev, Steve Horvath, Michael P. Snyder, Vittorio Sebastiano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract DNA methylation (DNAm) is one of the most reliable biomarkers of aging across mammalian tissues. While the age-dependent global loss of DNAm has been well characterized, DNAm gain is less characterized. Studies have demonstrated that CpGs wh
Externí odkaz:
https://doaj.org/article/903dd1a324284990bb38ba6fe77d4c37
Autor:
Summer Mengelkoch, Jeffrey Gassen, Shahar Lev-Ari, Jenna C. Alley, Sophia Miryam Schüssler-Fiorenza Rose, Michael P. Snyder, George M. Slavich
Publikováno v:
Stress, Vol 27, Iss 1 (2024)
AbstractDespite decades of stress research, there still exist substantial gaps in our understanding of how social, environmental, and biological factors interact and combine with developmental stressor exposures, cognitive appraisals of stressors, an
Externí odkaz:
https://doaj.org/article/a1d007b56fd748f9bf6180aed2cc51d6
Autor:
Fereshteh Jahanbani, Justin Cyril Sing, Rajan Douglas Maynard, Shaghayegh Jahanbani, Janet Dafoe, Whitney Dafoe, Nathan Jones, Kelvin J. Wallace, Azuravesta Rastan, Holden T. Maecker, Hannes L. Röst, Michael P. Snyder, Ronald W. Davis
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMyalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) presents substantial challenges in patient care due to its intricate multisystem nature, comorbidities, and global prevalence. The heterogeneity among patient populations, couple
Externí odkaz:
https://doaj.org/article/88c71aeb70374364a24f772a28f6611f
Autor:
Sarasa Isobe, Ramesh V. Nair, Helen Y. Kang, Lingli Wang, Jan-Renier Moonen, Tsutomu Shinohara, Aiqin Cao, Shalina Taylor, Shoichiro Otsuki, David P. Marciano, Rebecca L. Harper, Mir S. Adil, Chongyang Zhang, Mauro Lago-Docampo, Jakob Körbelin, Jesse M. Engreitz, Michael P. Snyder, Marlene Rabinovitch
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Pulmonary arterial hypertension (PAH) is a progressive disease in which pulmonary arterial (PA) endothelial cell (EC) dysfunction is associated with unrepaired DNA damage. BMPR2 is the most common genetic cause of PAH. We report that human P
Externí odkaz:
https://doaj.org/article/77e16fe3567e4a3f89266732e6c31cf1
Autor:
Calum Harvey, Marcel Weinreich, James A.K. Lee, Allan C. Shaw, Laura Ferraiuolo, Heather Mortiboys, Sai Zhang, Paul J. Hop, Ramona A.J. Zwamborn, Kristel van Eijk, Thomas H. Julian, Tobias Moll, Alfredo Iacoangeli, Ahmad Al Khleifat, John P. Quinn, Abigail L. Pfaff, Sulev Kõks, Joanna Poulton, Stephanie L. Battle, Dan E. Arking, Michael P. Snyder, Jan H. Veldink, Kevin P. Kenna, Pamela J. Shaw, Johnathan Cooper-Knock
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e24975- (2024)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving selective vulnerability of energy-intensive motor neurons (MNs). It has been unclear whether mitochondrial function is an upstream driver or a downstream modifier of n
Externí odkaz:
https://doaj.org/article/3a074f5bc5b844fb908962fcae463ee2
Autor:
Yashvardhan Jain, Leah L. Godwin, Yingnan Ju, Naveksha Sood, Ellen M. Quardokus, Andreas Bueckle, Teri Longacre, Aaron Horning, Yiing Lin, Edward D. Esplin, John W. Hickey, Michael P. Snyder, Nathan Heath Patterson, Jeffrey M. Spraggins, Katy Börner
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract The Human BioMolecular Atlas Program (HuBMAP) aims to compile a Human Reference Atlas (HRA) for the healthy adult body at the cellular level. Functional tissue units (FTUs), relevant for HRA construction, are of pathobiological significance.
Externí odkaz:
https://doaj.org/article/a82090e71a744dd18fb9cc682a3d9c64
Autor:
Min Yu, Yage Nie, Jiawen Yang, Shilun Yang, Rui Li, Varsha Rao, Xiaoyan Hu, Cheng Fang, Simeng Li, Dengpan Song, Fuyou Guo, Michael P. Snyder, Howard Y. Chang, Calvin J. Kuo, Jin Xu, Junlei Chang
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113392- (2023)
Summary: The blood-brain barrier (BBB) is primarily manifested by a variety of physiological properties of brain endothelial cells (ECs), but the molecular foundation for these properties remains incompletely clear. Here, we generate a comprehensive
Externí odkaz:
https://doaj.org/article/b5dca1762ab541118d63d893ef4ecbbc
Publikováno v:
Advances in Radiation Oncology, Vol 8, Iss 4, Pp 101173- (2023)
Purpose: This article presents enhancements to a 4-dimensional (4D) lung digital tomosynthesis (DTS) model introduced in a 2018 paper. That model was proposed as an adjunct to 4D computed tomography (4DCT) to improve tumor localization through artifa
Externí odkaz:
https://doaj.org/article/d9387bac662c4be3a032ba883d256c29
Autor:
Fahad A. Al-Muhanna, Alexa K. Dowdell, Abdulmohsen H. Al Eleq, Waleed I. Albaker, Andrew W. Brooks, Ali I. Al-Sultan, Abdullah M. Al-Rubaish, Khaled R. Alkharsah, Raed M. Sulaiman, Abdulaziz A. Al-Quorain, Cyril Cyrus, Rudaynah A. Alali, Chittibabu Vatte, Fred L. Robinson, Xin Zhou, Michael P. Snyder, Afnan F. Almuhanna, Brendan J. Keating, Brian D. Piening, Amein K. Al-Ali
Publikováno v:
BMC Microbiology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Large-scale gut microbiome sequencing has revealed key links between microbiome dysfunction and metabolic diseases such as type 2 diabetes (T2D). To date, these efforts have largely focused on Western populations, with few studies
Externí odkaz:
https://doaj.org/article/c8190e3aa79d4cf3b11d0c5dd6c1129f
Autor:
Md Mobashir Hasan Shandhi, Peter J. Cho, Ali R. Roghanizad, Karnika Singh, Will Wang, Oana M. Enache, Amanda Stern, Rami Sbahi, Bilge Tatar, Sean Fiscus, Qi Xuan Khoo, Yvonne Kuo, Xiao Lu, Joseph Hsieh, Alena Kalodzitsa, Amir Bahmani, Arash Alavi, Utsab Ray, Michael P. Snyder, Geoffrey S. Ginsburg, Dana K. Pasquale, Christopher W. Woods, Ryan J. Shaw, Jessilyn P. Dunn
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-13 (2022)
Abstract Mass surveillance testing can help control outbreaks of infectious diseases such as COVID-19. However, diagnostic test shortages are prevalent globally and continue to occur in the US with the onset of new COVID-19 variants and emerging dise
Externí odkaz:
https://doaj.org/article/6d71dce3bef84ace8313c62d5b632734