Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Michael P, Messenger"'
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background A Target Product Profile (TPP) outlines the necessary characteristics of an innovative product to address an unmet clinical need. TPPs could be used to better guide manufacturers in the development of ‘fit for purpose’ tests,
Externí odkaz:
https://doaj.org/article/5d7af6cb98044e7080a5a9fc1ad7a8d8
Autor:
Fiona M. Walter, Matthew J. Thompson, Ian Wellwood, Gary A. Abel, William Hamilton, Margaret Johnson, Georgios Lyratzopoulos, Michael P. Messenger, Richard D. Neal, Greg Rubin, Hardeep Singh, Anne Spencer, Stephen Sutton, Peter Vedsted, Jon D. Emery
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Novel diagnostic triage and testing strategies to support early detection of cancer could improve clinical outcomes. Most apparently promising diagnostic tests ultimately fail because of inadequate performance in real-world, low p
Externí odkaz:
https://doaj.org/article/4766b26373334f65b775a23246d5f69e
Autor:
Rosamonde E. Banks, Peter J. Selby, Gordon C. Jayson, Geoffrey Hall, Jonathan A. Ledermann, Cybil Adusei, Douglas Thompson, Sharon Jackson, Michael P. Messenger, Narinder Gahir, Tobias C. Wind, Alexandre Zougman, David A. Cairns, Rachel A. Craven, Michelle Hutchinson, Fiona Collinson
PDF file - 129K, Supplementary Table 1. Clinical characteristics of discovery cohort. Characteristics of 10 patients from experimental arm of ICON7 trial used in MS discovery experiment; Supplementary Table 2. Number of samples in each treatment arm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca87a7bcf7aebf149a79df8af69b28d
https://doi.org/10.1158/1078-0432.22450956
https://doi.org/10.1158/1078-0432.22450956
Autor:
Rosamonde E. Banks, Peter J. Selby, Gordon C. Jayson, Geoffrey Hall, Jonathan A. Ledermann, Cybil Adusei, Douglas Thompson, Sharon Jackson, Michael P. Messenger, Narinder Gahir, Tobias C. Wind, Alexandre Zougman, David A. Cairns, Rachel A. Craven, Michelle Hutchinson, Fiona Collinson
Purpose: The aim of this study was to identify and validate novel predictive and/or prognostic serum proteomic biomarkers in patients with epithelial ovarian cancer (EOC) treated as part of the phase III international ICON7 clinical trial.Experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b021a7a74c8ee688128104cc2bc6120c
https://doi.org/10.1158/1078-0432.c.6522060.v1
https://doi.org/10.1158/1078-0432.c.6522060.v1
Autor:
Rosamonde E. Banks, Peter J. Selby, Gordon C. Jayson, Geoffrey Hall, Jonathan A. Ledermann, Cybil Adusei, Douglas Thompson, Sharon Jackson, Michael P. Messenger, Narinder Gahir, Tobias C. Wind, Alexandre Zougman, David A. Cairns, Rachel A. Craven, Michelle Hutchinson, Fiona Collinson
PDF file - 58K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180cc48e8131758208ec94e64fa5c6be
https://doi.org/10.1158/1078-0432.22450968.v1
https://doi.org/10.1158/1078-0432.22450968.v1
Autor:
Rosamonde E. Banks, Peter J. Selby, Gordon C. Jayson, Geoffrey Hall, Jonathan A. Ledermann, Cybil Adusei, Douglas Thompson, Sharon Jackson, Michael P. Messenger, Narinder Gahir, Tobias C. Wind, Alexandre Zougman, David A. Cairns, Rachel A. Craven, Michelle Hutchinson, Fiona Collinson
PDF file - 269K, Supplementary Figure 1: Differences in AGP, mesothelin and FLT4 concentrations between responders and non responders in the discovery sample set (n=10); Supplementary Figure 2: Progression-free survival in validation cohort I; Supple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bbcdfc88725b142d316b2f09c24b05
https://doi.org/10.1158/1078-0432.22450965
https://doi.org/10.1158/1078-0432.22450965
Autor:
Rosamonde E. Banks, Peter J. Selby, Gordon C. Jayson, Geoffrey Hall, Jonathan A. Ledermann, Cybil Adusei, Douglas Thompson, Sharon Jackson, Michael P. Messenger, Narinder Gahir, Tobias C. Wind, Alexandre Zougman, David A. Cairns, Rachel A. Craven, Michelle Hutchinson, Fiona Collinson
PDF file - 963K, Supplementary Figure 4: Correlation between biomarkers investigated in validation cohort I; Supplementary Figure 5: Longitudinal patterns in AGP concentration in validation cohort I; Supplementary Figure 6. Prognostic and predictive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c448f485a3d325b2eb6aa35e77d88261
https://doi.org/10.1158/1078-0432.22450962
https://doi.org/10.1158/1078-0432.22450962
Autor:
Peter J Selby, Rosamonde E Banks, Walter Gregory, Jenny Hewison, William Rosenberg, Douglas G Altman, Jonathan J Deeks, Christopher McCabe, Julie Parkes, Catharine Sturgeon, Douglas Thompson, Maureen Twiddy, Janine Bestall, Joan Bedlington, Tilly Hale, Jacqueline Dinnes, Marc Jones, Andrew Lewington, Michael P Messenger, Vicky Napp, Alice Sitch, Sudeep Tanwar, Naveen S Vasudev, Paul Baxter, Sue Bell, David A Cairns, Nicola Calder, Neil Corrigan, Francesco Del Galdo, Peter Heudtlass, Nick Hornigold, Claire Hulme, Michelle Hutchinson, Carys Lippiatt, Tobias Livingstone, Roberta Longo, Matthew Potton, Stephanie Roberts, Sheryl Sim, Sebastian Trainor, Matthew Welberry Smith, James Neuberger, Douglas Thorburn, Paul Richardson, John Christie, Neil Sheerin, William McKane, Paul Gibbs, Anusha Edwards, Naeem Soomro, Adebanji Adeyoju, Grant D Stewart, David Hrouda
Publikováno v:
Programme Grants for Applied Research, Vol 6, Iss 3 (2018)
Background: Protein biomarkers with associations with the activity and outcomes of diseases are being identified by modern proteomic technologies. They may be simple, accessible, cheap and safe tests that can inform diagnosis, prognosis, treatment se
Externí odkaz:
https://doaj.org/article/387a42efb3ae4638b9f4a6e973b265ca
Publikováno v:
Health Technol Assess
Health Technology Assessment, Vol 25, Iss 21 (2021)
Health Technology Assessment, Vol 25, Iss 21 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019. At the time of writing (October 2020), the number of cases of COVID-19 had been approaching 38 million and more than 1 million deaths were
Autor:
Nicholas GD Masca, Elizabeth MA Hensor, Victoria R Cornelius, Francesca M Buffa, Helen M Marriott, James M Eales, Michael P Messenger, Amy E Anderson, Chris Boot, Catey Bunce, Robert D Goldin, Jessica Harris, Rod F Hinchliffe, Hiba Junaid, Shaun Kingston, Carmen Martin-Ruiz, Christopher P Nelson, Janet Peacock, Paul T Seed, Bethany Shinkins, Karl J Staples, Jamie Toombs, Adam KA Wright, M Dawn Teare
Publikováno v:
eLife, Vol 4 (2015)
Lack of reproducibility is an ongoing problem in some areas of the biomedical sciences. Poor experimental design and a failure to engage with experienced statisticians at key stages in the design and analysis of experiments are two factors that contr
Externí odkaz:
https://doaj.org/article/a0d7e699f1c042edb9b4707dd4859347