Zobrazeno 1 - 10
of 1 813
pro vyhledávání: '"Michael P, Manns"'
Autor:
Nataliia Petriv, Huizhen Suo, Inga Hochnadel, Kai Timrott, Nina Bondarenko, Lavinia Neubert, Elena Reinhard, Nils Jedicke, Patrick Kaufhold, Carlos Alberto Guzmán, Ralf Lichtinghagen, Michael P. Manns, Heike Bantel, Tetyana Yevsa
Publikováno v:
JHEP Reports, Vol 6, Iss 12, Pp 101189- (2024)
Background & Aims: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death. Metabolic dysfunction-associated steatotic liver disease (MASLD) is a significant cause of HCC. Current treatment options for HCC are very limited.
Externí odkaz:
https://doaj.org/article/ef1620cb3a1343f29ec24dfc1537cb8e
Autor:
Janine Dywicki, Laura Elisa Buitrago-Molina, Fatih Noyan, Jerome Schlue, Konstantinos Iordanidis, Michael P. Manns, Heiner Wedemeyer, Elmar Jaeckel, Matthias Hardtke-Wolenski
Publikováno v:
European Journal of Medical Research, Vol 27, Iss 1, Pp 1-8 (2022)
Abstract Autoimmune hepatitis (AIH) is a chronic immune-mediated inflammatory liver disease. It is known that AIH originates not from the spleen but from the liver itself. Nonetheless, most details of the etiology and pathophysiology are unknown. We
Externí odkaz:
https://doaj.org/article/b06c23f9432545069705c91450ad0e1a
Autor:
Benjamin Maasoumy, Patrick Ingiliz, Christoph D. Spinner, Christiane Cordes, Hans-Jürgen Stellbrink, Julian Schulze zur Wiesch, Stephan M. Schneeweiß, Katja Deterding, Tobias Müller, Julia Kahlhöfer, Petra Dörge, Maria von Karpowitz, Michael P. Manns, Heiner Wedemeyer, Markus Cornberg
Publikováno v:
JHEP Reports, Vol 5, Iss 3, Pp 100650- (2023)
Background & Aims: EASL guidelines recommend 8 weeks of treatment with sofosbuvir plus velpatasvir (SOF/VEL) for the treatment of acute or recently acquired HCV infection, but only 6- and 12-week data are available. Therefore, the aim of this study w
Externí odkaz:
https://doaj.org/article/612f548a04634195960c6a4eb99bc11d
Autor:
Lisa Sandmann, Cihan Yurdaydin, Katja Deterding, Benjamin Heidrich, Svenja Hardtke, Patrick Lehmann, Birgit Bremer, Michael P. Manns, Markus Cornberg, Heiner Wedemeyer, Benjamin Maasoumy, HIDIT‐II Study Group
Publikováno v:
Hepatology Communications, Vol 6, Iss 3, Pp 480-495 (2022)
Standard treatment of hepatitis delta virus (HDV) infection remains pegylated‐interferon alfa (peg‐IFNα) in most centers, which is not only associated with rather low efficacy but several adverse events. Hepatitis B core‐related antigen (HBcrA
Externí odkaz:
https://doaj.org/article/492aebed2abf4e6fb1bb337cc53e4fff
Autor:
Lena Stockhoff, Theresa Muellner‐Bucsics, Antoaneta A. Markova, Marie Schultalbers, Simone A. Keimburg, Tammo L. Tergast, Jan B. Hinrichs, Nicolas Simon, Svetlana Gerbel, Michael P. Manns, Mattias Mandorfer, Markus Cornberg, Bernhard C. Meyer, Heiner Wedemeyer, Thomas Reiberger, Benjamin Maasoumy
Publikováno v:
Hepatology Communications, Vol 6, Iss 3, Pp 621-632 (2022)
Transjugular intrahepatic portosystemic shunt (TIPS) is an effective treatment for portal hypertension‐related complications. However, careful selection of patients is crucial. The aim of this study was to evaluate the prognostic value of serum cho
Externí odkaz:
https://doaj.org/article/ae6e93fd54f64b7e95f7f25c2792aacf
Autor:
Marie Griemsmann, Tammo L. Tergast, Nicolas Simon, Abdul-Rahman Kabbani, Michael P. Manns, Heiner Wedemeyer, Markus Cornberg, Benjamin Maasoumy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract There are considerable differences between males and females regarding the etiology, progression and outcome of liver diseases. Infections are a frequent and severe complication in these patients. This study aimed to examine sex specific dif
Externí odkaz:
https://doaj.org/article/4e5bfd2d7eb747059e3e1b9bd478dac8
Autor:
Janine Dywicki, Laura Elisa Buitrago‐Molina, Fatih Noyan, Ana C. Davalos‐Misslitz, Katharina L. Hupa‐Breier, Maren Lieber, Martin Hapke, Jerome Schlue, Christine S. Falk, Solaiman Raha, Immo Prinz, Christian Koenecke, Michael P. Manns, Heiner Wedemeyer, Matthias Hardtke‐Wolenski, Elmar Jaeckel
Publikováno v:
Hepatology Communications, Vol 6, Iss 2, Pp 320-333 (2022)
Nonalcoholic steatohepatitis (NASH) is induced by steatosis and metabolic inflammation. While involvement of the innate immune response has been shown, the role of the adaptive immune response in NASH remains controversial. Likewise, the role of regu
Externí odkaz:
https://doaj.org/article/c74f2c70e32d41ff853767285a092092
Autor:
Holger Andreas Volk, Tobias Welte, Claudia Schulz, Andreas Nitsche, Thomas Illig, Lothar Kreienbrock, Maren von Köckritz-Blickwede, Michael Peter Manns, Nele Alexandra ten Hagen, Friederike Twele, Sebastian Meller, Lisa Wijnen, Clara Schoneberg, Albert Osterhaus, Anna-Lena Boeck, Konstantin Boeck, Viktoria Bonda, Veronika Pilchová, Franziska Karola Kaiser, Mariana Gonzalez Hernandez, Hans Ebbers, Julia Hinsenkamp, Isabell Pink, Nora Drick, Andreas Puyskens, Christiane Ernst, Michael Engels, Esther Schalke
Publikováno v:
BMJ Global Health, Vol 7, Iss 11 (2022)
Introduction Previous research demonstrated that medical scent detection dogs have the ability to distinguish SARS-CoV-2 positive from negative samples with high diagnostic accuracy. To deploy these dogs as a reliable screening method, it is mandator
Externí odkaz:
https://doaj.org/article/3c6da634b23f4f49811e9512da3361d3
Autor:
Sandra Bufe, Artur Zimmermann, Sarina Ravens, Immo Prinz, Laura Elisa Buitrago-Molina, Robert Geffers, Norman Woller, Florian Kühnel, Steven R. Talbot, Fatih Noyan, Michael Peter Manns, Heiner Wedemeyer, Matthias Hardtke-Wolenski, Elmar Jaeckel, Ana C. Davalos-Misslitz
Publikováno v:
Liver Cancer (2022)
Background: Checkpoint inhibitors act on exhausted CD8+ T cells and restore their effector function in chronic infections and cancer. The underlying mechanisms of action appear to differ between different types of cancer and are not yet fully underst
Externí odkaz:
https://doaj.org/article/965c2a4212154815948f7cc4a347137a
Autor:
Huizhen Suo, Inga Hochnadel, Nataliia Petriv, Raimo Franke, Jennifer Schmidt, Nataliia Limanska, Alisa Tugai, Nils Jedicke, Mark Broenstrup, Michael P. Manns, Tetyana Yevsa
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
In this study, we investigated compounds of plant and mushroom origin belonging to Traditional Chinese Medicine (TCM) and to Traditional Tibetan Medicine (TTM): a sandy beige mushroom Trametes robiniophila Murr, commonly known as Huaier/TCM as well a
Externí odkaz:
https://doaj.org/article/d9ac0c7f6e2140fda45fedc3fad56d1b