Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Michael P, Fischbein"'
Autor:
Alex R. Dalal, MD, Albert J. Pedroza, MD, Aravind Krishnan, MD, Yan Min, MD, MS, Emily Tognozzi, PA-C, Nobu Yokoyama, MD, Ken Nakamura, MD, Olivia R. Mitchel, BS, Michael Baiocchi, PhD, Y. Joseph Woo, MD, John W. MacArthur, MD, Michael P. Fischbein, MD, PhD
Publikováno v:
JTCVS Open, Vol 13, Iss , Pp 9-19 (2023)
Objective: To evaluate the effect of perioperative allogeneic packed red blood cell (RBC) transfusion during aortic root replacement. Method: We reviewed patients undergoing aortic root replacement at our institution between March 2014 and April 2020
Externí odkaz:
https://doaj.org/article/07327f7dcdd3474bb97c01fa04c96be2
Autor:
Hye Sook Shin, Akshara Thakore, Yuko Tada, Albert J. Pedroza, Gentaro Ikeda, Ian Y. Chen, Doreen Chan, Kevin J. Jaatinen, Shin Yajima, Eric M. Pfrender, Masashi Kawamura, Phillip C. Yang, Joseph C. Wu, Eric A. Appel, Michael P. Fischbein, YJoseph Woo, Yasuhiro Shudo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-21 (2022)
Abstract Many cell-based therapies are challenged by the poor localization of introduced cells and the use of biomaterial scaffolds with questionable biocompatibility or bio-functionality. Endothelial progenitor cells (EPCs), a popular cell type used
Externí odkaz:
https://doaj.org/article/20ab15817ad2445c8d8fd81a36008cce
Autor:
Peter Chiu, MD, MS, Hong-Pyo Lee, PhD, MS, Alex R. Dalal, MD, Tiffany Koyano, BA, Marie Nguyen, BA, Andrew J. Connolly, MD, PhD, Ovijit Chaudhuri, PhD, Michael P. Fischbein, MD, PhD
Publikováno v:
JVS - Vascular Science, Vol 2, Iss , Pp 235-246 (2021)
Objective: Current guidelines for prophylactic replacement of the thoracic aorta, primarily based on size alone, may not be adequate in identifying patients at risk for either progression of disease or aortic catastrophe. We undertook the current stu
Externí odkaz:
https://doaj.org/article/ee17b1ad83ba4dc6b2b100fedb6dc208
Autor:
Cristiana Iosef, Albert J. Pedroza, Jason Z. Cui, Alex R. Dalal, Mamoru Arakawa, Yasushi Tashima, Tiffany K. Koyano, Grayson Burdon, Samantha M. P. Churovich, Joshua O. Orrick, Mitchel Pariani, Michael P. Fischbein
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the FBN1 gene that produces wide disease phenotypic variability. The lack of ample genotype–phenotype correlation hinders translational study development aimed at
Externí odkaz:
https://doaj.org/article/5f51d52d33394a82b68928fa4c927f13
Autor:
Albert J. Pedroza, Alex R. Dalal, Rohan Shad, Nobu Yokoyama, Ken Nakamura, Olivia Mitchel, Casey Gilles, William Hiesinger, Michael P. Fischbein
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:971-978
Background: Smooth muscle cell (SMC) phenotypic reprogramming toward a mixed synthetic-proteolytic state is a central feature of aortic root aneurysm in Marfan syndrome (MFS). Previous work identified Klf4 as a potential mediator of SMC plasticity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44a09ab2ecf7787e173f307b9166755e
https://doi.org/10.1161/atvbaha.122.318509
https://doi.org/10.1161/atvbaha.122.318509
Autor:
Yasushi Tashima, Hao He, Jason Z. Cui, Albert J. Pedroza, Ken Nakamura, Nobu Yokoyama, Cristiana Iosef, Grayson Burdon, Tiffany Koyano, Atsushi Yamaguchi, Michael P. Fischbein
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 20 (2020)
Background Male patients with Marfan syndrome have a higher risk of aortic events and root dilatation compared with females. The role androgens play during Marfan syndrome aneurysm development in males remains unknown. We hypothesized that androgens
Externí odkaz:
https://doaj.org/article/350c3d55cf2d4cf18ea4784b97464174
Autor:
Nathan L. Liang, Michael D. Dake, Michael P. Fischbein, Joseph E. Bavaria, Nimesh D. Desai, Gustavo S. Oderich, Michael J. Singh, Mark Fillinger, Bjoern D. Suckow, Jon S. Matsumura, Himanshu J. Patel, Michel S. Makaroun
Publikováno v:
European Journal of Vascular and Endovascular Surgery. 64:639-645
Aortic aneurysms involving aortic arch vessels are anatomically unsuitable for standard thoracic endovascular repair (TEVAR) without cervical debranching of the arch vessels. Three year outcomes of a single branched thoracic endograft following previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d59acf00c9608fbf4def8662acaba5e
https://doi.org/10.1016/j.ejvs.2022.08.003
https://doi.org/10.1016/j.ejvs.2022.08.003
Autor:
Albert J. Pedroza, Alex R. Dalal, Rohan Shad, Nobu Yokoyama, Ken Nakamura, Paul Cheng, Robert C. Wirka, Olivia Mitchel, Michael Baiocchi, William Hiesinger, Thomas Quertermous, Michael P. Fischbein
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42:1154-1168
Background: Aortic root smooth muscle cells (SMC) develop from both the second heart field (SHF) and neural crest. Disparate responses to disease-causing Fbn1 variants by these lineages are proposed to promote focal aortic root aneurysm formation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be331ce48a9c856556936d2b3bf4c8a8
https://doi.org/10.1161/atvbaha.122.317381
https://doi.org/10.1161/atvbaha.122.317381
Autor:
Valery Turner, Eva Maret, Juyong B. Kim, Marina Codari, Virginia Hinostroza, Domenico Mastrodicasa, A. Claire Watkins, William F. Fearon, Michael P. Fischbein, Francois Haddad, Martin J. Willemink, Dominik Fleischmann
Publikováno v:
Academic Radiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a98a8e5f59aa100980578214996a6c9b
https://doi.org/10.1016/j.acra.2023.03.014
https://doi.org/10.1016/j.acra.2023.03.014
Autor:
Ken Nakamura, Alex R. Dalal, Nobu Yokoyama, Albert J. Pedroza, Sho Kusadokoro, Olivia Mitchel, Casey Gilles, Bahar Masoudian, Matthew Leipzig, Kerriann M. Casey, William Hiesinger, Tetsuro Uchida, Michael P. Fischbein
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology.
BACKGROUND: To delineate the effects of integrin αv signaling in Marfan syndrome (MFS) and examine the potential efficacy of integrin αv blockade as a therapeutic strategy for MFS aneurysms. METHODS: Induced pluripotent stem cells were differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0e22263a480e83d76c36d112e1d14b2
https://doi.org/10.1161/atvbaha.122.318448
https://doi.org/10.1161/atvbaha.122.318448