Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael P, Fatt"'
Autor:
Mekayla A. Storer, Denis Gallagher, Michael P. Fatt, Jaclin V. Simonetta, David R. Kaplan, Freda D. Miller
Publikováno v:
Stem Cell Reports, Vol 10, Iss 5, Pp 1464-1480 (2018)
Summary: Circulating systemic factors can regulate adult neural stem cell (NSC) biology, but the identity of these circulating cues is still being defined. Here, we have focused on the cytokine interleukin-6 (IL-6), since increased circulating levels
Externí odkaz:
https://doaj.org/article/413de4bec0704eb2b2049d3c965c3187
Autor:
Michael P, Fatt, Lina M, Tran, Gisella, Vetere, Mekayla A, Storer, Jaclin V, Simonetta, Freda D, Miller, Paul W, Frankland, David R, Kaplan
Publikováno v:
Stem Cell Reports. 17:259-275
Senescent cells are responsible, in part, for tissue decline during aging. Here, we focused on CNS neural precursor cells (NPCs) to ask if this is because senescent cells in stem cell niches impair precursor-mediated tissue maintenance. We demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca76ff23d24ae637320deeaca309b6a0
https://doi.org/10.1016/j.stemcr.2021.12.010
https://doi.org/10.1016/j.stemcr.2021.12.010
Autor:
Michael P. Fatt, Mekayla Storer, David L. Kaplan, Freda D. Miller, Jaclin V. Simonetta, Denis Gallagher
Publikováno v:
Stem Cell Reports, Vol 10, Iss 5, Pp 1464-1480 (2018)
Stem Cell Reports
Stem Cell Reports
Summary Circulating systemic factors can regulate adult neural stem cell (NSC) biology, but the identity of these circulating cues is still being defined. Here, we have focused on the cytokine interleukin-6 (IL-6), since increased circulating levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb67680fe04829acd576ceda6d29ba2
http://www.sciencedirect.com/science/article/pii/S2213671118301358
http://www.sciencedirect.com/science/article/pii/S2213671118301358
Autor:
Fredric E. Wondisford, Ling He, Karolynn Hsu, Freda D. Miller, David L. Kaplan, Jing Wang, Michael P. Fatt
Publikováno v:
Stem Cell Reports, Vol 5, Iss 6, Pp 988-995 (2015)
Stem Cell Reports
Stem Cell Reports
Summary The recruitment of endogenous adult neural stem cells for brain repair is a promising regenerative therapeutic strategy. This strategy involves stimulation of multiple stages of adult neural stem cell development, including proliferation, sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08247c3aff739af0fe96eca7af199da1
http://www.sciencedirect.com/science/article/pii/S2213671115003112
http://www.sciencedirect.com/science/article/pii/S2213671115003112
Publikováno v:
Cell Cycle
p63 is a member of the p53 family that regulates the survival of neural precursors in the adult brain. However, the relative importance of p63 in the developing brain is still unclear, since embryonic p63(-/-) mice display no apparent deficits in neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a294b4f82d794654979364309c690db
http://europepmc.org/articles/PMC4825551
http://europepmc.org/articles/PMC4825551
Autor:
Cindi M. Morshead, Parvati Dadwal, Fredric E. Wondisford, Laleh Sinai, Freda D. Miller, Neemat Mahmud, Ashkan Azimi, Michael P. Fatt
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 5, Iss 2, Pp 166-173 (2015)
Stem Cell Reports, Vol 5, Iss 2, Pp 166-173 (2015)
Summary The development of cell replacement strategies to repair the injured brain has gained considerable attention, with a particular interest in mobilizing endogenous neural stem and progenitor cells (known as neural precursor cells [NPCs]) to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deee7a453468985da20e0eea6bb11125
http://europepmc.org/articles/PMC4618663
http://europepmc.org/articles/PMC4618663
Publikováno v:
Cell Death & Differentiation. 21:1546-1559
The p53 family members p73 and p63 have been implicated in various aspects of stem cell regulation. Here, we have asked whether they work together to regulate stem cell biology, focusing upon neural precursor cells (NPCs) in the adult murine brain. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce0099a2d79abfc319dbfd21fb821ec
https://doi.org/10.1038/cdd.2014.61
https://doi.org/10.1038/cdd.2014.61
Autor:
Cameron L. Woodard, Gonzalo I. Cancino, Denis Gallagher, Michael P. Fatt, Freda D. Miller, John P. Vessey, Cindi M. Morshead, Andrée Gauthier-Fisher, Masashi Fujitani, Andreea A. Norman, Guang Yang, Nadia Sachewsky, David R. Kaplan, Knut Woltjen
Publikováno v:
Cell Stem Cell. 13(5):564-576
SummaryThe mechanisms that regulate the establishment of adult stem cell pools during normal and perturbed mammalian development are still largely unknown. Here, we asked whether a maternal cytokine surge, which occurs during human maternal infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b53915e216064cbf0a693182f53f87c
Autor:
Chandrasagar B. Dugani, Paul W. Frankland, Michael P. Fatt, Sheena A. Josselyn, Freda D. Miller, David L. Kaplan, Elsa R. Flores, Gonzalo I. Cancino, Adelaide P. Yiu
Publikováno v:
Journal of Neuroscience. 33:12569-12585
The molecular mechanisms that regulate adult neural precursor cell (NPC) survival, and thus maintain adult neurogenesis, are not well defined. Here, we investigate the role of p63, a p53 family member, in adult NPC function in mice. Conditional ablat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028c60a4c4ea06fb06c8a58266fbbb39
https://doi.org/10.1523/jneurosci.1251-13.2013
https://doi.org/10.1523/jneurosci.1251-13.2013
Publikováno v:
International Journal of Developmental Neuroscience. 47:13-13
The p53 family members p73 and p63 have been implicated in various aspects of stem cell regulation. Here, we have asked whether they work together to regulate stem cell biology, focusing upon neural precursor cells (NPCs) in the adult murine brain. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa3832501d4e51584a4a15469a3c461a
https://doi.org/10.1016/j.ijdevneu.2015.04.045
https://doi.org/10.1016/j.ijdevneu.2015.04.045