Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Michael Otter"'
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54138 (2013)
Formalin fixation is a mainstay of modern histopathologic analysis, yet the practice is poorly standardized and a significant potential source of preanalytical errors. Concerns of workflow and turnaround time drive interest in developing shorter fixa
Externí odkaz:
https://doaj.org/article/d90b425d9cfa487c812d258e2df54f80
Autor:
Maria Westerhoff, Michael Otter, Heidi L. Kenerson, Raymond S. Yeung, Melissa L. Lerch, Geoffrey S. Baird, Abbey Theiss, David Chafin
Publikováno v:
Cell and Tissue Banking
Precision tissue diagnostics rely on high quality input specimens so that assay results are not affected by artifact, but advances in collection and processing of tissue specimens have lagged behind innovations in diagnostic assay development. Theref
Autor:
Jessica Moe, Jane A. Buxton, Yueqiao Elle Wang, Tamara Chavez, Damian Feldman-Kiss, Charotte Marr, Roy A. Purssell, Michael Otterstatter
Publikováno v:
Harm Reduction Journal, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background In British Columbia, Canada, smoking is the most common modality of drug use among people who die of opioid toxicity. We aimed to assess oxygen saturation (SpO2) while people smoked opioids during a pilot study that introduced con
Externí odkaz:
https://doaj.org/article/d67f9bd12c4e466680e2cac20e3c0344
Publikováno v:
Biopreservation and Biobanking
The development of precision testing for disease diagnosis has advanced medicine by specifically matching patients with drugs to treat specific diseases. High-quality diagnostics start with high-quality tissue specimens. The development and optimizat
Publikováno v:
Current Pathobiology Reports
Purpose of Review Studying and developing preanalytical tools and technologies for the purpose of obtaining high-quality samples for histological assays is a growing field. Currently, there does not exist a standard practice for collecting, fixing, a
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology
Supplemental Digital Content is available in the text.
Personalized medicine promises diagnosis and treatment of disease at the individual level and relies heavily on clinical specimen integrity and diagnostic assay quality. Preanalytics, the co
Personalized medicine promises diagnosis and treatment of disease at the individual level and relies heavily on clinical specimen integrity and diagnostic assay quality. Preanalytics, the co
Autor:
Melissa L. Lerch, Geoffrey S. Baird, Maria Westerhoff, Heidi L. Kenerson, Michael Otter, Abbey Theiss, David Chafin, Raymond S. Yeung
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Phosphoproteins are the key indicators of signaling network pathway activation. Many disease treatment therapies are designed to inhibit these pathways and effective diagnostics are required to evaluate the efficacy of these treatments. Phosphoprotei
Autor:
Binay Adhikari, Younathan Abdia, Notice Ringa, Felicity Clemens, Sunny Mak, Caren Rose, Naveed Z. Janjua, Michael Otterstatter, Michael A. Irvine
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundThe COVID-19 pandemic has highlighted health disparities, especially among specific population groups. This study examines the spatial relationship between the proportion of visible minorities (VM), occupation types and COVID-19 infection i
Externí odkaz:
https://doaj.org/article/3e715ae3a2d1451d88e5b0ce12ade8d3
Autor:
Sarafa A Iyaniwura, Notice Ringa, Prince A Adu, Sunny Mak, Naveed Z Janjua, Michael A Irvine, Michael Otterstatter
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 5, p e1011123 (2023)
The outbreak of the severe acute respiratory syndrome coronavirus 2 started in Wuhan, China, towards the end of 2019 and spread worldwide. The rapid spread of the disease can be attributed to many factors including its high infectiousness and the hig
Externí odkaz:
https://doaj.org/article/71bf464a282d47b2974a63f8eb5eb750
Publikováno v:
Journal of medical imaging (Bellingham, Wash.). 3(1)
The preservation of certain labile cancer biomarkers with formaldehyde-based fixatives can be considerably affected by preanalytical factors such as quality of fixation. Currently, there are no technologies capable of quantifying a fixative's concent