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pro vyhledávání: '"Michael Ol Steinmetz"'
Autor:
Michael Ol Steinmetz, Katja Bargsten, J. Fernando Díaz, Andrea E. Prota, May Marsh, José Manuel Andreu, Carmen Cuevas, Marc Liniger, Christian M. Neuhaus, Karl-Heinz Altmann
Publikováno v:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
The recent success of antibody–drug conjugates (ADCs) in the treatment of cancer has led to a revived interest in microtubule-destabilizing agents. Here, we determined the high-resolution crystal structure of the complex between tubulin and maytans