Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Michael Ohene-Nyako"'
Autor:
Michael Ohene-Nyako, Sara R. Nass, Hope T. Richard, Robert Lukande, Melanie R. Nicol, MaryPeace McRae, Pamela E. Knapp, Kurt F. Hauser
Publikováno v:
ASN Neuro, Vol 15 (2023)
Aberrant phosphorylation and subsequent aggregation of the trans-activation response (TAR) element DNA binding protein 43 (TDP-43) is a common feature of multiple neurodegenerative disorders and contributes to disease severity. Here, we investigated
Externí odkaz:
https://doaj.org/article/40944578bd644a5e9ee9fadf91aff448
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Opioid use disorder (OUD) is a critical problem that contributes to the spread of HIV and may intrinsically worsen neuroHIV. Despite the advent of combined antiretroviral therapies (cART), about half of persons infected with HIV (PWH) experience cogn
Externí odkaz:
https://doaj.org/article/794d623f615d423caa4d007d496ffa56
Autor:
Sara R. Nass, Yun K. Hahn, Michael Ohene-Nyako, Virginia D. McLane, M. Imad Damaj, Leroy R. Thacker, Pamela E. Knapp, Kurt F. Hauser
Publikováno v:
Viruses, Vol 15, Iss 3, p 590 (2023)
Opioid use disorder (OUD) and HIV are comorbid epidemics that can increase depression. HIV and the viral protein Tat can directly induce neuronal injury within reward and emotionality brain circuitry, including the prefrontal cortex (PFC). Such damag
Externí odkaz:
https://doaj.org/article/5268e4498a2d4d1f9e58f8b18d1037fa
Autor:
Amanda L Persons, Brinda D Bradaric, Hemraj B Dodiya, Michael Ohene-Nyako, Christopher B Forsyth, Ali Keshavarzian, Maliha Shaikh, T Celeste Napier
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190078 (2018)
The integrity and function of the gut is impaired in HIV-infected individuals, and gut pathogenesis may play a role in several HIV-associated disorders. Methamphetamine is a popular illicit drug abused by HIV-infected individuals. However, the effect
Externí odkaz:
https://doaj.org/article/3040d23670db43798d452256ea8748da
Autor:
Arianna R. S. Lark, Lindsay K. Silva, Sara R. Nass, Michael G. Marone, Michael Ohene-Nyako, Therese M. Ihrig, William D. Marks, Viktor Yarotskyy, A. Rory McQuiston, Pamela E. Knapp, Kurt F. Hauser
Publikováno v:
Cellular and Molecular Neurobiology. 43:1105-1127
Publikováno v:
Current opinion in neurobiology. 78
Opioid use disorder (OUD) has become a national crisis and contributes to the spread of human immunodeficiency virus (HIV) infection. Emerging evidence and advances in experimental models, methodology, and our understanding of disease processes at th
Publikováno v:
Eur J Neurosci
Combined antiretroviral therapy for HIV infection reduces plasma viral load and prolongs life. However, the brain is a viral reservoir, and pathologies such as cognitive decline and blood–brain barrier (BBB) disruption persist. Methamphetamine abus
Autor:
Crystal R, Leibrand, Jason J, Paris, Austin M, Jones, Michael, Ohene-Nyako, Kara M, Rademeyer, Sara R, Nass, Woong-Ki, Kim, Pamela E, Knapp, Kurt F, Hauser, MaryPeace, McRae
Publikováno v:
Neuroscience Letters. 788:136852
Despite advances in the treatment of human immunodeficiency virus (HIV), approximately one-half of people infected with HIV (PWH) experience neurocognitive impairment. Opioid use disorder (OUD) can exacerbate the cognitive and pathological changes se
Publikováno v:
Neurosci Lett
Opiate abuse is prevalent among HIV-infected individuals and may exacerbate HIV-associated age-related neurocognitive disorders. However, the extent to which HIV and opiates converge to accelerate pathological traits indicative of brain aging remains