Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael Oestergaard"'
Autor:
Noriko Satake, Connie Duong, Sakiko Yoshida, Michael Oestergaard, Cathy Chen, Rachael Peralta, Shuling Guo, Punit P Seth, Yueju Li, Laurel Beckett, Jong Chung, Jan Nolta, Nitin Nitin, Joseph M Tuscano
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 632-642 (2016)
Abstract The exponential rise in molecular and genomic data has generated a vast array of therapeutic targets. Oligonucleotide-based technologies to down regulate these molecular targets have promising therapeutic efficacy. However, there is relative
Externí odkaz:
https://doaj.org/article/88710ac9246b4db68143aad6fabf9036
Autor:
Michael Oestergaard, Minji Jo, Andres Berdeja, Punit P. Seth, Alfred E. Chappell, Thazha P. Prakash, Eric E. Swayze, Ruchi Gupta, Hans Gaus
Publikováno v:
Nucleic Acids Research
Conjugation of antisense oligonucleotide (ASO) with a variety of distinct lipophilic moieties like fatty acids and cholesterol increases ASO accumulation and activity in multiple tissues. While lipid conjugation increases tissue exposure in mice and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2138afdb15ff2bbbbb611c101151385d
https://doi.org/10.1093/nar/gkaa164
https://doi.org/10.1093/nar/gkaa164
Autor:
Rachael Peralta, Punit P. Seth, Nitin Nitin, Shuling Guo, Laurel A. Beckett, Michael Oestergaard, Noriko Satake, Michael Fazio, Yueju Li, Connie P.M. Duong, Sakiko Yoshida, Cathy Chen
Publikováno v:
Nanomedicine
Neuroblastoma (NB) is the most common extracranial solid tumor in children. The outcomes for aggressive forms of NB remain poor. The aim of this study was to develop a new molecular-targeted therapy for NB using an antisense oligonucleotide (ASO) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10a3ac4c63f79b6149e5a5df755d1d7
https://escholarship.org/uc/item/07g836nr
https://escholarship.org/uc/item/07g836nr
Autor:
Joseph Tuscano, Jan A. Nolta, Laurel A. Beckett, Connie P.M. Duong, Rachael Peralta, Noriko Satake, Shuling Guo, Punit P. Seth, Michael Oestergaard, Jong Hee Chung, Yueju Li, Cathy Chen, Sakiko Yoshida, Nitin Nitin
Publikováno v:
Molecular medicine (Cambridge, Mass.), vol 22, iss 1
Molecular Medicine, Vol 22, Iss 1, Pp 632-642 (2016)
Molecular Medicine, Vol 22, Iss 1, Pp 632-642 (2016)
The exponential rise in molecular and genomic data has generated a vast array of therapeutic targets. Oligonucleotide-based technologies to down regulate these molecular targets have promising therapeutic efficacy. However, there is relatively limite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0b5275a1d846d786f7602aa7e9545c
https://escholarship.org/uc/item/330690s7
https://escholarship.org/uc/item/330690s7
Autor:
Crystal N. Doty, Eric E. Swayze, Michael R. Hayden, Nicholas S. Caron, Holly Kordasiewicz, Susan M. Freier, C. Frank Bennet, Yuanyun Xie, Amber L. Southwell, Niels H. Skotte, Boguslaw Felczak, Punit P. Seth, Erika B. Villanueva, Michael Oestergaard
Publikováno v:
Molecular Therapy. 23
Huntington disease (HD) is a dominant, genetic neurodegenerative disease characterized by progressive loss of voluntary motor control, psychiatric disturbance, and cognitive decline, for which there is currently no disease-modifying therapy. HD is ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ca6d18226ecf67b3ce7e1af720b41d
Autor:
Nitin Nitin, Connie P.M. Duong, Shuling Guo, Sakiko Yoshida, Joseph Tuscano, Noriko Satake, Punit P. Seth, Michael Oestergaard, Jan A. Nolta, Cathy Chen
Publikováno v:
Blood. 124:3719-3719
Precursor B cell (preB) acute lymphoblastic leukemia (ALL) is the most common cancer in children. Despite aggressive treatment, current approaches for preB ALL have significant limitations with a cure rate of only 30% in certain subtypes. In addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe505aed431456168cc771b70be3048e
https://doi.org/10.1182/blood.v124.21.3719.3719
https://doi.org/10.1182/blood.v124.21.3719.3719