Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Michael Oer"'
Publikováno v:
Hepatology Communications, Vol 3, Iss 8, Pp 1137-1150 (2019)
Because of their high regenerative potential, stem cells are an ideal resource for development of therapies that replace injured tissue mass and restore function in patients with end‐stage liver diseases. Using a rat model of bile duct ligation (BD
Externí odkaz:
https://doaj.org/article/91df9d2d8a494f7a89398a300dd2eddd
Autor:
Niklas Benedikt Pepper, Hans Theodor Eich, Michael Müther, Michael Oertel, Stephan Rehn, Dorothee Cäcilia Spille, Walter Stummer
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract Background Despite improvements in surgical as well as adjuvant therapies over the last decades, the prognosis for patients with glioblastoma remains poor. Five-Aminolevulinic acid (5-ALA) induced porphyrins are already used for fluorescence
Externí odkaz:
https://doaj.org/article/f3cff0fb0d0641168e753c0de641fb38
Autor:
Marta Melis, Rebecca Marino, Jianmin Tian, Carla Johnson, Rahil Sethi, Michael Oertel, Ira J. Fox, Joseph Locker
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 3, Pp 453-479 (2024)
Background & Aims: HNF4α, a master regulator of liver development and the mature hepatocyte phenotype, is down-regulated in chronic and inflammatory liver disease. We used contemporary transcriptomics and epigenomics to study the cause and effects o
Externí odkaz:
https://doaj.org/article/270e6dc5cdb04a1fb26e7c7fe9fb3567
Autor:
Yoojeong Park, Shikai Hu, Minwook Kim, Michael Oertel, Aatur Singhi, Satdarshan P. Monga, Silvia Liu, Sungjin Ko
Publikováno v:
Cells, Vol 13, Iss 17, p 1451 (2024)
Combined hepatocellular carcinoma–cholangiocarcinoma (cHCC-CCA) is a challenging primary liver cancer subtype with limited treatment options and a devastating prognosis. Recent studies have underscored the context-dependent roles of SOX9 in liver c
Externí odkaz:
https://doaj.org/article/04e2b014816644ecbe72025e66b0c2b2
Autor:
Alice Heger, MS, Khaled Elsayad, PhD, Christian Kandler, MD, Jan Siats, MD, Michael Oertel, MD, Christopher Kittel, MD, Hans Theodor Eich, PhD
Publikováno v:
JAAD International, Vol 17, Iss , Pp 53-54 (2024)
Externí odkaz:
https://doaj.org/article/662c8069d6014d9d8eadd7415e48edc3
Autor:
Eva Sickinger, Kathrin Schmid, Michael Oer, Tobias Meyer, Jan Schultess, Hans-Bertram Braun, David Daghfal
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 97:115033
Despite improvement in vaccinations, Hepatitis B remains a major health concern due to the difficulty of prevention even in low endemic areas such as Europe. In this report we describe the performance characteristics of the new HBsAg Next Qualitative
Autor:
Sowmya Mekala, Ravi Rai, Samantha Loretta Reed, Bill Bowen, George K. Michalopoulos, Joseph Locker, Reben Raeman, Michael Oertel
Publikováno v:
Cells, Vol 13, Iss 7, p 649 (2024)
Background/Aim: Activin A is involved in the pathogenesis of human liver diseases, but its therapeutic targeting is not fully explored. Here, we tested the effect of novel, highly specific small-molecule-based activin A antagonists (NUCC-474/555) in
Externí odkaz:
https://doaj.org/article/645a524c9cd2403da680adf786157b77
Autor:
Mary Ayers, Karis Kosar, Yuhua Xue, Chhavi Goel, Matthew Carson, Elizabeth Lee, Silvia Liu, Eva Brooks, Pamela Cornuet, Michael Oertel, Bharat Bhushan, Kari Nejak-Bowen
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 6, Pp 895-921 (2023)
Background & Aims: β-Catenin, the effector molecule of the Wnt signaling pathway, has been shown to play a crucial role in bile acid homeostasis through direct inhibition of farnesoid X receptor (FXR), which has pleiotropic effects on bile acid home
Externí odkaz:
https://doaj.org/article/d2779cf093ec4bc390894535e93c2550
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-5 (2022)
Highlights Malignant melanoma patients reveal a characteristic and distinct immunological pattern. Elevated levels of soluble PD-L1 induced by previous immunotherapy were found. There were decreased levels of soluble PD-L2 in comparison to healthy co
Externí odkaz:
https://doaj.org/article/fda0aa5584b2472ea490ef1873f3a065
Autor:
Michael Oertel, Dominik Hering, Christian Baues, Christopher Kittel, Michael Fuchs, Jan Kriz, Kai Kröger, Dirk Vordermark, Klaus Herfarth, Rita Engenhart-Cabillic, Peter Lukas, Uwe Haverkamp, Peter Borchmann, Hans Theodor Eich
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionThe German Hodgkin Study Group (GHSG) HD17 trial established the omission of radiotherapy (RT) for patients with early-stage unfavorable Hodgkin lymphoma being PET-negative after 2 cycles of BEACOPP escalated plus 2 cycles of ABVD. This p
Externí odkaz:
https://doaj.org/article/bbcff74f33a749ce844db4900fab4337