Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Michael Oelgeschläger"'
Autor:
Marc Audebert, Ann-Sophie Assmann, Amaya Azqueta, Pavel Babica, Emilio Benfenati, Sylvie Bortoli, Peter Bouwman, Albert Braeuning, Tanja Burgdorf, Xavier Coumoul, Kloé Debizet, Maria Dusinska, Norman Ertych, Jörg Fahrer, Verena Fetz, Ludovic Le Hégarat, Adela López de Cerain, Harm J. Heusinkveld, Kevin Hogeveen, Miriam N. Jacobs, Mirjam Luijten, Giuseppa Raitano, Cynthia Recoules, Elise Rundén-Pran, Mariam Saleh, Iva Sovadinová, Martina Stampar, Lea Thibol, Céline Tomkiewicz, Ariane Vettorazzi, Bob Van de Water, Naouale El Yamani, Bojana Zegura, Michael Oelgeschläger
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Carcinogenic chemicals, or their metabolites, can be classified as genotoxic or non-genotoxic carcinogens (NGTxCs). Genotoxic compounds induce DNA damage, which can be detected by an established in vitro and in vivo battery of genotoxicity assays. Fo
Externí odkaz:
https://doaj.org/article/bb67b7cd857c45a58747146a121d489d
Publikováno v:
Environment International, Vol 164, Iss , Pp 107256- (2022)
Various in vitro model systems have been established over the last decades to understand physiological processes, the causalities of diseases and the response of humans to environmental and industrial chemicals or therapeutic drugs. Common to all is
Externí odkaz:
https://doaj.org/article/9f774c4484a1475db9a72e89b1e4555e
Autor:
Saskia Klutzny, Marja Kornhuber, Andrea Morger, Gilbert Schönfelder, Andrea Volkamer, Michael Oelgeschläger, Sebastian Dunst
Publikováno v:
Environment International, Vol 158, Iss , Pp 106947- (2022)
Background: Exposure to environmental chemicals that interfere with normal estrogen function can lead to adverse health effects, including cancer. High-throughput screening (HTS) approaches facilitate the efficient identification and characterization
Externí odkaz:
https://doaj.org/article/92c737196a274e44bc84e57d624e9852
Publikováno v:
Environment International, Vol 149, Iss , Pp 106411- (2021)
Adverse health effects that are caused by endocrine disrupting chemicals (EDCs) in the environment, food or consumer products are of high public concern. The identification and characterization of EDCs including substances with estrogenic activity st
Externí odkaz:
https://doaj.org/article/c2ef7f9ffb384deb8d0e5dc5c0d4bc69
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100224- (2020)
Summary: Growth and offspring count are two commonly determined toxicological endpoints for chemical- or gene-induced developmental and reproductive effects in Caenorhabditis elegans. Here, we present a protocol for a 96 h, medium-throughput assay, a
Externí odkaz:
https://doaj.org/article/119207da1b4448b5b06f4f0ca20bd86c
Autor:
Philip Bischoff, Marja Kornhuber, Sebastian Dunst, Jakob Zell, Beatrix Fauler, Thorsten Mielke, Anna V. Taubenberger, Jochen Guck, Michael Oelgeschläger, Gilbert Schönfelder
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101683- (2020)
Summary: Estrogens play an important role in the development and progression of human cancers, particularly in breast cancer. Breast cancer progression depends on the malignant destabilization of adherens junctions (AJs) and disruption of tissue inte
Externí odkaz:
https://doaj.org/article/1736b18cf81242179682094d09b0391d
Autor:
Johanna Ndikung, Dorothe Storm, Norman Violet, Achim Kramer, Gilbert Schönfelder, Norman Ertych, Michael Oelgeschläger
Publikováno v:
Environment International, Vol 134, Iss , Pp - (2020)
Background: The growing requirement of hazard and risk assessment of environmental chemicals and the efforts to minimize animal testing, increases the demand for innovative and predictive in vitro test systems in toxicology, reflecting the physiologi
Externí odkaz:
https://doaj.org/article/dcb8e196d2f1442fb7438b9ff3fb0101
Autor:
Christopher Weidner, Matthias Steinfath, Elisa Opitz, Michael Oelgeschläger, Gilbert Schönfelder
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 8, Pp 831-838 (2016)
Abstract The mouse is the main model organism used to study the functions of human genes because most biological processes in the mouse are highly conserved in humans. Recent reports that compared identical transcriptomic datasets of human inflammato
Externí odkaz:
https://doaj.org/article/217355b0515c4d73942f4d39037f9b55
Autor:
Lena Smirnova, Katharina Block, Alexandra Sittka, Michael Oelgeschläger, Andrea E M Seiler, Andreas Luch
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98892 (2014)
Studying chemical disturbances during neural differentiation of murine embryonic stem cells (mESCs) has been established as an alternative in vitro testing approach for the identification of developmental neurotoxicants. miRNAs represent a class of s
Externí odkaz:
https://doaj.org/article/775750d3786c47be961953a0ae2283f8
Autor:
Anne Marie Vinggaard, Marja Lamoree, Escher, B. I., P Antignac, J., Martin Scholze, Tina Kold Jensen, Matthias Herzler, Marc Audebert, Timo Hamers, Andreas Kortenkamp, Francois Busquet, Matteo Piumatti, Gaud Dervilly, Valente, M. J., Ronan Cariou, Moteau, S., Michael Oelgeschläger, Kostja Renko, Sebastian Schmeisser, Dieter Maier, Laursen, L. L.
Publikováno v:
Vinggaard, A M, Lamoree, M, Escher, B I, Antignac, J-P, Scholze, M, Jensen, T K, Herzler, M, Audebert, M, Hamers, T, Kortenkamp, A, Busquet, F, Piumatti, M, Dervilly, G, Valente, M J, Cariou, R, Moteau, S, Oelgeschläger, M, Renko, K, Schmeisser, S, Maier, D & Laursen, L L 2022, ' PANORAMIX: Providing risk assessments of complex real-life mixtures for the protection of Europe’s citizens and the environment ', ICT2022-The XVIth International Congress of Toxicology, Maastricht, Netherlands, 18/09/22-21/09/22 pp. S217 . < https://www.sciencedirect.com/science/article/pii/S0378427422015272?via%3Dihub >
Vrije Universiteit Amsterdam
ICT2022-The XVIth International Congress of Toxicology
Vrije Universiteit Amsterdam
ICT2022-The XVIth International Congress of Toxicology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b9f6bace42b815e9ff1a1f4850fe2407
https://research.vu.nl/en/publications/cc96b2ba-e0e5-451f-9d1e-6c5792057cf3
https://research.vu.nl/en/publications/cc96b2ba-e0e5-451f-9d1e-6c5792057cf3
