Zobrazeno 1 - 6
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pro vyhledávání: '"Michael O. Onwochei"'
Publikováno v:
Journal of Cardiovascular Pharmacology. 31:10-17
The primary objective of this study was to test the hypothesis that an increase in the alpha1-adrenoceptor tone would potentiate the myocardial biphasic contractile response to inorganic phosphate [Pi, the substrate of Na/Pi-cotransporter (NP)]. A se
Autor:
Michael O. Onwochei
Publikováno v:
Journal of cardiovascular pharmacology. 25(5)
The interaction of cardiac sodium/phosphate (Na + /Pi)-cotransporter and the phosphoinositide pathway (PIP) in influencing myocardial contraction was investigated. Specifically, the study was performed to determine if myocardial positive inotropic re
Autor:
Michael O. Onwochei
Publikováno v:
Journal of cardiovascular pharmacology. 22(4)
Na+/Pi-cotransporter utilizes the electrochemical gradient of sodium to transport inorganic phosphate (Pi) into the cells of various organs, including heart. Because changes in the activity of Na+/Pi-cotransporter may influence the concentrations of
Publikováno v:
Journal of Hypertension. 4:493-499
Calcium uptake and efflux were studied in aortic tissues of three inbred rat strains; spontaneously hypertensive rats (SHR), inbred Dahl salt-sensitive rats (S/JR) and inbred Dahl salt-resistant (R/JR) rats. Previously, we showed that a single geneti
Autor:
Michael O. Onwochei, John P. Rapp
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 188(4)
We investigated the effect of sodium chloride and adrenergic agents on the release of atrial natriuretic factor (ANF) using working heart-lung preparations from Dahl salt-hypertension sensitive (S) and Dahl salt-hypertension resistant (R) rats. High
Autor:
S. Jamal Mustafa, Michael O. Onwochei
Publikováno v:
Life sciences. 36(2)
A linear relationship was found between coronary flow and adenosine release during the course of reactive hyperemia. Isolated guinea pig heart was perfused with a modified Krebs Ringer bicarbonate buffer containing 2.0 mM pyruvate. Hyperemia was indu