Výsledky vyhledávání - "Michael O. Boylan"

Gastric inhibitory polypeptide immunoneutralization attenuates development of obesity in mice

Autor: Milos Tatalovic, M. Michael Wolfe, Patricia A. Glazebrook, Michael O. Boylan

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 309:E1008-E1018

Previous reports have suggested that the abrogation of gastric inhibitory polypeptide (GIP) signaling could be exploited to prevent and treat obesity and obesity-related disorders in humans. This study was designed to determine whether immunoneutrali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3151176752f3245e09a2357d6e304cfb
https://doi.org/10.1152/ajpendo.00345.2015

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Effects of gastric inhibitory polypeptide (GIP) immunoneutralization on mouse motor coordination and memory

Autor: Hiroyuki Arakawa, M. Michael Wolfe, Michael O. Boylan, Claire Y. Zhang

Publikováno v: Peptides. 125:170227

Gastric inhibitory polypeptide (GIP) is a regulatory peptide expressed in the mammalian upper small intestine, and both GIP and its receptor (GIPR) are expressed in the cortex and hippocampus regions of the brain as well. While learning and memory de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc386e5688635ddf8e7adff91134558
https://doi.org/10.1016/j.peptides.2019.170227

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Microscale sample preparation for PCR of C. difficile infected stool

Autor: Michael O. Boylan, Catherine M. Klapperich, Chris Atkinson, John H. Schwartz, Aaron C. Bartoo, Sara Gillers, Madhumita Mahalanabis, Satish K. Singh

Publikováno v: Journal of Microbiological Methods. 78:203-207

In this paper, we describe the design of a microfluidic sample preparation chip for human stool samples infected with Clostridium difficile. We established a polymerase chain reaction able to distinguish C. difficile in the presence of several other

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82c9661ce5f5b484d88363fc0efbd47
https://doi.org/10.1016/j.mimet.2009.05.020

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Glucose-dependent Insulinotropic Polypeptide (GIP) Stimulates Transepithelial Glucose Transport

Autor: Selvi Krishnan, Michael O. Boylan, M. Michael Wolfe, John H. Schwartz, Aaron C. Bartoo, Satish K. Singh

Publikováno v: Obesity. 16:2412-2416

The purpose of this study was to characterize the effects of glucose-dependent insulinotropic peptide (GIP) on small intestinal glucose transport in vitro. Stripped proximal jejunum from fasted mice was mounted in Ussing chambers. The serosal side wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eaec33dbdfc74dc9510055b9d89059e
https://doi.org/10.1038/oby.2008.393

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Sp1/Sp3 binding is associated with cell-specific expression of the glucose-dependent insulinotropic polypeptide receptor gene

Autor: Michael O. Boylan, Lisa I. Jepeal, M. Michael Wolfe

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 290:E1287-E1295

The physiological effects of glucose-dependent insulinotropic polypeptide (GIP) are mediated through specific receptors expressed on target cells. Because aberrant GIP receptor ( GIPR) expression has been implicated in abnormal GIP responses associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca194646be10df1db2add01ae9da56c
https://doi.org/10.1152/ajpendo.00535.2005

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