Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michael O. Baffi"'
Publikováno v:
Developmental Biology. 296(2):363-374
Previously, we showed that deletion of the TGF-beta type II receptor (Tgfbr2) in Type II Collagen (Col2a) expressing cells results in defects in the development of the axial skeleton. Defects included a reduction in size and alterations in the shape
Publikováno v:
Developmental Biology. 276:124-142
Members of the TGF-beta superfamily are secreted signaling proteins that regulate many aspects of development including growth and differentiation in skeletal tissue. There are three isoforms of TGF-beta that act through the same heteromeric receptor
Publikováno v:
Journal of Biological Chemistry. 278:15495-15504
Interferon regulatory factor (IRF)-7 is activated in response to virus infection and stimulates the transcription of a set of cellular genes involved in host antiviral defense. The mechanism by which IRF-7 is activated and cooperates with other trans
Publikováno v:
European Journal of Biochemistry. 269:6142-6151
Virus infection results in the activation of a set of cellular genes involved in host antiviral defense. IRF-3 has been identified as a critical transcription factor in this process. The activation mechanism of IRF-3 is not fully elucidated, yet it i
Autor:
Andra R. Frost, Dung-Tsa Chen, Michael R. Crowley, Teodora Nicola, Michael O. Baffi, Rosa Serra
Publikováno v:
Differentiation; research in biological diversity. 74(1)
To determine the role of transforming growth factor-beta (TGF-beta) signaling in mammary development and tumor formation, we previously generated transgenic mice that expressed a dominant-negative form of the TGF-beta type II receptor (DNIIR) under t