Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Michael Noji"'
Autor:
Laura Ohl, Amanda Kuhs, Ryan Pluck, Emily Durham, Michael Noji, Nathan D. Philip, Zoltan Arany, Rebecca C. Ahrens-Nicklas
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 39, Iss , Pp 101091- (2024)
Branched chain ketoacid dehydrogenase kinase (BCKDK) deficiency is a recently described inherited neurometabolic disorder of branched chain amino acid (BCAA) metabolism implying increased BCAA catabolism. It has been hypothesized that a severe reduct
Externí odkaz:
https://doaj.org/article/f818517ac67c4b70a2e2d604114071d0
Autor:
Sydney Campbell, Clementina Mesaros, Luke Izzo, Hayley Affronti, Michael Noji, Bethany E Schaffer, Tiffany Tsang, Kathryn Sun, Sophie Trefely, Salisa Kruijning, John Blenis, Ian A Blair, Kathryn E Wellen
Publikováno v:
eLife, Vol 10 (2021)
Tumors frequently exhibit aberrant glycosylation, which can impact cancer progression and therapeutic responses. The hexosamine biosynthesis pathway (HBP) produces uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a major substrate for glycosylat
Externí odkaz:
https://doaj.org/article/5ce0bca35ac845fba57a2e6f6f790030
Autor:
Sara C Campbell, Paul J Wisniewski, Michael Noji, Lora R McGuinness, Max M Häggblom, Stanley A Lightfoot, Laurie B Joseph, Lee J Kerkhof
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150502 (2016)
BACKGROUND:The gut microbiota is now known to play an important role contributing to inflammatory-based chronic diseases. This study examined intestinal integrity/inflammation and the gut microbial communities in sedentary and exercising mice present
Externí odkaz:
https://doaj.org/article/5718b05706054683bceba89613892937
Insulin-stimulated adipocytes secrete lactate to promote endothelial fatty acid uptake and transport
Autor:
Boa Kim, Marc R. Bornstein, Raffiu Mohammed, Michael D. Neinast, Kathryn E. Wellen, Ayon Ibrahim, Michael Noji, Zolt Arany, Kristina Li
Publikováno v:
J Cell Sci
Insulin stimulates adipose tissue to extract fatty acids from circulation and sequester them inside adipose cells. How fatty acids are transported across the capillary endothelial barrier, and how this process is regulated, remains unclear. We modele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7f8d3cd3b98f83c474a406eafe4733
https://europepmc.org/articles/PMC8729779/
https://europepmc.org/articles/PMC8729779/
Autor:
Ian A. Blair, Kathryn Sun, Sydney L. Campbell, Sophie Trefely, Michael Noji, Salisa Kruijning, Bethany E Schaffer, Tiffany Tsang, John Blenis, Hayley C. Affronti, Kathryn E. Wellen, Clementina Mesaros, Luke Izzo
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Tumors frequently exhibit aberrant glycosylation, which can impact cancer progression and therapeutic responses. The hexosamine biosynthesis pathway (HBP) produces uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a major substrate for glycosylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f21e539ba4448cd5c13d6ff889c7db0
https://elifesciences.org/articles/62644
https://elifesciences.org/articles/62644
Autor:
Enri Profka, Rahim R. Rizi, Anthony A. Mancuso, Stephen Kadlecek, Ryan M. Kiefer, Michael Noji, Mehrdad Pourfathi, Terence P. Gade, Charles N. Weber, Sarmad Siddiqui, Austin R. Pantel
Publikováno v:
Metabolites
Volume 11
Issue 9
Metabolites, Vol 11, Iss 576, p 576 (2021)
Volume 11
Issue 9
Metabolites, Vol 11, Iss 576, p 576 (2021)
In this study, we describe new methods for studying cancer cell metabolism with hyperpolarized 13C magnetic resonance spectroscopy (HP 13C MRS) that will enable quantitative studies at low oxygen concentrations. Cultured hepatocellular carcinoma cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c9441836824d302f559d36bf209ce9
Autor:
John Blenis, Ian A. Blair, Hayley C. Affronti, Kathryn E. Wellen, Michael Noji, Kathryn Sun, Sydney L. Campbell, Bethany E Schaffer, Salisa Kruijning, Sophie Trefely, Tiffany Tsang, Luke Izzo, Clementina Mesaros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02a686d8814cb3b93b3271bf828b6df7
https://doi.org/10.7554/elife.62644.sa2
https://doi.org/10.7554/elife.62644.sa2
Autor:
Stephanie Stransky, Anna Bostwick, Simone Sidoli, Claudia D. Lovell, Katharina Huber, Clementina Mesaros, Helen Jiang, Luke Izzo, Michael Noji, Mary T. Doan, Joyce Liu, Jimmy P. Xu, Jay Singh, Nathaniel W. Snyder, Juliane G. Bogner-Strauss, Steven Zhao, Kathryn E. Wellen, Hannah L. Pepper, J. Eduardo Rame, Eliana von Krusenstiern, Kenneth Bedi, Sophie Trefely
Publikováno v:
SSRN Electronic Journal.
Quantitative sub-cellular metabolomic measurements can yield crucial insights into the roles of metabolites in cellular processes, but are subject to multiple confounding factors. We developed Stable Isotope Labeling of Essential nutrients in cell Cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97f016367e1747dde9243d5c9cce275c
https://doi.org/10.2139/ssrn.3885983
https://doi.org/10.2139/ssrn.3885983
Autor:
Luke Izzo, Helen Jiang, Mary T. Doan, Claudia D. Lovell, Anna Bostwick, Clementina Mesaros, Stephanie Stransky, Jimmy P. Xu, Kenneth Bedi, Michael Noji, Juliane G. Bogner-Strauss, Sophie Trefely, Jay Singh, Nathaniel W. Snyder, Eliana von Krusenstiern, Katharina Huber, Steven Zhao, Simone Sidoli, Joyce Liu, J. Eduardo Rame, Kathryn E. Wellen, Hannah L. Pepper
Summary Metabolism is highly compartmentalized within cells, and the sub-cellular distribution of metabolites determines their use. Quantitative sub-cellular metabolomic measurements can yield crucial insights into the roles of metabolites in cellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dad211a7416dd475f55082bd1431394
https://doi.org/10.1101/2020.07.30.229468
https://doi.org/10.1101/2020.07.30.229468
Autor:
Michael Noji, David J. Tischfield, Michelle R. Denburg, Austin R. Pantel, Anthony Mancuso, Gregory J. Nadolski, Ryan M. Kiefer, O. Johnson, Terence P. Gade, Enri Profka, Stephen Pickup, Sarmad Siddiqui, Stephen Kadlecek, Emma E. Furth, Mehrdad Pourfathi, Daniel Ackerman, Stephen J. Hunt, Nicholas R. Perkons
Publikováno v:
Hepatology
Background and aims Advances in cancer treatment have improved survival; however, local recurrence and metastatic disease-the principal causes of cancer mortality-have limited the ability to achieve durable remissions. Local recurrences arise from la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85eb0af247df22af88a390b38e4e94f8
https://europepmc.org/articles/PMC7307779/
https://europepmc.org/articles/PMC7307779/