Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael Nickells"'
Publikováno v:
Journal of General Virology. 86:413-421
Persistent infection of mouse neuroblastoma NB41A3 cells with yellow fever 17D virus generates viral variants which exhibit defective cell penetration, poor cell-to-cell spread, small plaque size and reduced growth efficiency, caused by substitution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328b2fc633bb0a27e80d8fd33e168434
https://doi.org/10.1099/vir.0.80314-0
https://doi.org/10.1099/vir.0.80314-0
Autor:
Michael Nickells, Thomas J. Chambers
Publikováno v:
Journal of Virology. 77:12232-12242
A molecular clone of mouse-neuroadapted yellow fever 17D virus (SPYF-MN) was used to identify critical determinants of viral neuroinvasiveness in a SCID mouse model. Virus derived from this clone differs from nonneuroinvasive YF5.2iv virus at 29 nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85031a3b2b6fd086e58045a8ae138f4
https://doi.org/10.1128/jvi.77.22.12232-12242.2003
https://doi.org/10.1128/jvi.77.22.12232-12242.2003
Autor:
Michael Nickells, Yujia Tang, Deborah A. Droll, Vannakambadi K. Ganesh, Thomas J. Chambers, Yan Liang, Krishna H. M. Murthy
Publikováno v:
The Journal of general virology. 86(Pt 5)
A series of 46 charged-to-alanine mutations in the yellow fever virus NS2B–NS3 protease, previously characterized in cell-free and transient cellular expression systems, was tested for their effects on virus recovery. Four distinct plaque phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80bd824a6547608a4b7aaf4b343304ad
https://pubmed.ncbi.nlm.nih.gov/15831952
https://pubmed.ncbi.nlm.nih.gov/15831952
Autor:
Edgardo Hembrador, Thomas J. Chambers, Xiaofeng Fan, Lynn B. Dustin, Adrian M. DiBisceglie, Deborah A. Droll, Michael Nickells, Tiffany Slater
Publikováno v:
Journal of virology. 79(5)
A series of 29 patients undergoing treatment for chronic hepatitis C virus (HCV) genotype 1 infection with pegylated alpha-2a interferon plus ribavirin were studied for patterns of response to antiviral therapy and viral quasispecies evolution. All p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d2b8736f734f252b83c2801ddb9003
https://pubmed.ncbi.nlm.nih.gov/15709027
https://pubmed.ncbi.nlm.nih.gov/15709027
Autor:
Thomas J. Chambers, Michael Nickells
Publikováno v:
Journal of virology. 75(22)
A neuroadapted strain of yellow fever virus (YFV) 17D derived from a multiply mouse brain-passaged virus (Porterfield YF17D) was additionally passaged in SCID and normal mice. The virulence properties of this virus (SPYF) could be distinguished from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ea43c7d9bd9d28e3a4d7dda2eb2a21
https://pubmed.ncbi.nlm.nih.gov/11602731
https://pubmed.ncbi.nlm.nih.gov/11602731
Publikováno v:
Virology. (1):41-49
A yellow fever (YFV) 17D virus variant, which causes persistent infection of mouse neuroblastoma cells associated with defective cell penetration and small plaque size, yielded plaque-revertant viruses from cells transfected with viral transcripts en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb80e7df8d01a0367943ca1b0f9c9dd0