Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Michael Neumaier"'
Autor:
Jochen J. Schoettler, Kathrin Brohm, Sonani Mindt, Evelyn Jäger, Bianka Hahn, Tanja Fuderer, Holger A. Lindner, Verena Schneider-Lindner, Joerg Krebs, Michael Neumaier, Manfred Thiel, Franz-Simon Centner
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6391 (2024)
Tissue hypoxia is associated with the development of organ dysfunction and death in critically ill patients commonly captured using blood lactate. The kinetic parameters of serial lactate evaluations are superior at predicting mortality compared with
Externí odkaz:
https://doaj.org/article/cf9dc77cc8104e1ca38d7020510938cf
Autor:
Norman J. Beauchamp, R. Nick Bryan, Marilyn M. Bui, Gabriel P. Krestin, Geraldine B. McGinty, Carolyn C. Meltzer, Michael Neumaier
Publikováno v:
Insights into Imaging, Vol 14, Iss 1, Pp 1-13 (2023)
Key points Although an overall boon to clinical diagnosis, increasingly voluminous, diverse, and fragmented diagnostic data can overwhelm physicians and frustrate patients. Data are gathered and processed within “silos” of the diagnostic discipli
Externí odkaz:
https://doaj.org/article/93d0994a35c945468daa0abd2859b713
Autor:
Qingyu Xu, Alexander Streuer, Johann-Christoph Jann, Eva Altrock, Nanni Schmitt, Johanna Flach, Carla Sens-Albert, Felicitas Rapp, Julia Wolf, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Mariia Kuzina, Ahmed Jawhar, Ali Darwich, Cleo-Aron Weis, Alexander Marx, Patrick Wuchter, Victor Costina, Evelyn Jäger, Elena Sperk, Michael Neumaier, Alice Fabarius, Georgia Metzgeroth, Florian Nolte, Laurenz Steiner, Pavel A. Levkin, Mohamad Jawhar, Wolf-Karsten Hofmann, Vladimir Riabov, Daniel Nowak
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Hypomethylating agents, such as 5-Azacytidine (5-AZA), are standard of care for patients with myelodysplastic and myeloid malignancies, however response rates are limited and risk of relapses high. Here the authors show that inhibition of lysyl oxida
Externí odkaz:
https://doaj.org/article/91b523f59ac547d99572fb13b46e1d2f
Autor:
Maximilian Kittel, Preetha Moorthy, Sonika Rao, Marie Halfmann, Margot Thiaucourt, Maximilian Strauß, Verena Haselmann, Nandhini Santhanam, Fabian Siegel, Michael Neumaier
Publikováno v:
Digital Health, Vol 9 (2023)
Background A major challenge in healthcare is the interpretation of the constantly increasing amount of clinical data of interest to inpatients for diagnosis and therapy. It is vital to accurately structure and represent data from different sources t
Externí odkaz:
https://doaj.org/article/b5c55babb9614296add4eba053f504e3
Autor:
Anna Sophia Jauch, Sebastian A. Wohlfeil, Céline Weller, Bianca Dietsch, Verena Häfele, Ana Stojanovic, Maximilian Kittel, Hendrik Nolte, Adelheid Cerwenka, Michael Neumaier, Kai Schledzewski, Carsten Sticht, Philipp-Sebastian Reiners-Koch, Sergij Goerdt, Cyrill Géraud
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Hyaluronan receptor LYVE-1 is expressed by liver sinusoidal endothelial cells (LSEC), lymphatic endothelial cells and specialized macrophages. Besides binding to hyaluronan, LYVE-1 can mediate adhesion of leukocytes and cancer cel
Externí odkaz:
https://doaj.org/article/7e8fd3d8dbfa4f958989dc52cbddebc7
Autor:
Catharina Gerhards, Marlene Steingass, Alexandra Heininger, Bettina Lange, Michael Hetjens, Marlis Gerigk, Michael Neumaier, Osman Evliyaoglu, Maximilian Kittel
Publikováno v:
Vaccines, Vol 12, Iss 2, p 163 (2024)
Background: The aim of the rapid introduction of vaccines during the COVID-19 pandemic was a reduction in SARS-CoV-2 transmission and a less frequent occurrence of severe COVID-19 courses. Thus, we evaluated COVID-19 severity in vaccinated individual
Externí odkaz:
https://doaj.org/article/02b70f94995d457581db48ddd77d982a
Autor:
Maren Hedtke, Rodrigo Pessoa Rejas, Matthias F. Froelich, Volker Ast, Angelika Duda, Laura Mirbach, Victor Costina, Uwe M. Martens, Ralf‐Dieter Hofheinz, Michael Neumaier, Verena Haselmann
Publikováno v:
Molecular Oncology, Vol 16, Iss 10, Pp 2042-2056 (2022)
The analysis of circulating tumor DNA (ctDNA) is at the threshold of implementation into standard care for colorectal cancer (CRC) patients. However, data about the clinical utility of liquid profiling (LP), its acceptance by clinicians, and its inte
Externí odkaz:
https://doaj.org/article/c1e5149860064c5e8fd192d932a6be65
Autor:
Franz-Simon Centner, Jochen J. Schoettler, Kathrin Brohm, Sonani Mindt, Evelyn Jäger, Bianka Hahn, Tanja Fuderer, Holger A. Lindner, Verena Schneider-Lindner, Joerg Krebs, Michael Neumaier, Manfred Thiel
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12600 (2023)
A common final pathway of pathogenetic mechanisms in septic organ dysfunction and death is a lack or non-utilization of oxygen. Plasma concentrations of lactate serve as surrogates for the oxygen-deficiency-induced imbalance between energy supply and
Externí odkaz:
https://doaj.org/article/4b1fb4b7ac5848efbee902653baf5b17
Autor:
Matthias Otto, Yannik Kropp, Evelyn Jäger, Michael Neumaier, Manfred Thiel, Michael Quintel, Charalambos Tsagogiorgas
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2080 (2023)
Mechanically ventilated patients suffering from acute respiratory distress syndrome (ARDS) frequently receive aerosolized iloprost. Because of prostacyclin’s short half-life, prolonged inhalative administration might improve its clinical efficacy.
Externí odkaz:
https://doaj.org/article/0090a898fc064002b5375be9eabd8afc
Autor:
Catharina Gerhards, Verena Haselmann, Samuel F. Schaible, Volker Ast, Maximilian Kittel, Manfred Thiel, Alexander Hertel, Stefan O. Schoenberg, Michael Neumaier, Matthias F. Froelich
Publikováno v:
Microorganisms, Vol 11, Iss 7, p 1740 (2023)
Background: Severe courses and high hospitalization rates were ubiquitous during the first pandemic SARS-CoV-2 waves. Thus, we aimed to examine whether integrative diagnostics may aid in identifying vulnerable patients using crucial data and material
Externí odkaz:
https://doaj.org/article/596a3e4a143644c19946d242c04206bf