Výsledky vyhledávání - "Michael Needels"

Akademický článek

709 Peptidyl IL-2/15Rβγc-restricted agonists, highly-attenuated and linked to anti-PD-1 antibodies to achieve selectivity and amplified potency in stimulating PD-1high lymphocytes

Autor: William Dower, Alice Bakker, Steven Cwirla, Prarthana Joshi, Praechompoo Pongtornpipat, Blake Williams, Michael Needels, Ronald Barrett

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

Externí odkaz: https://doaj.org/article/1b97f15b8df443b49bcae65a6577cdad

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Akademický článek

567 MDK1319/MDK-701: A potent fully efficacious peptidyl agonist of IL-7Rαγc, designed with no reference to cytokine or receptor structure and unrelated to IL-7, fused to an Fc-domain for PK enhancement

Autor: William Dower, Alice Bakker, Steven Cwirla, Prarthana Joshi, Praechompoo Pongtornpipat, Blake Williams, Sandra Wang, Michael Needels, Ronald Barrett

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)

Externí odkaz: https://doaj.org/article/39219be9b5974bbeaf2f38cc3bb3e06a

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Akademický článek

691 MDK-271: A dual function molecule consisting of empirically-designed peptidyl agonists of IL-2/15Rβγc and IL-7Rαγc, unrelated to IL-2, IL-15, or IL-7, incorporated into a bispecific Fc fusion protein

Autor: William Dower, Alice Bakker, Steven Cwirla, Prarthana Joshi, Praechompoo Pongtornpipat, Blake Williams, Sandra Wang, Michael Needels, Ronald Barrett

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)

Externí odkaz: https://doaj.org/article/57d3a382552e40e1ac2426429045bc03

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Akademický článek

566 MDK-202: An empirically-designed peptidyl agonist of the IL-2/15βγc receptor, devoid of Rα interaction, unrelated to IL-2 or IL-15, and fused to an Fc-domain for PK enhancement

Autor: William Dower, Alice Bakker, Steven Cwirla, Prarthana Joshi, Praechompoo Pongtornpipat, Blake Williams, Sandra Wang, Michael Needels, Ronald Barrett

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)

Externí odkaz: https://doaj.org/article/accd91a16d9c485a85884167210aa877

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1097 MDK1654: a branched synthetic peptide that activates both the IL-7 receptor and the βγc form of the IL-2/15 receptor

Autor: Inkyung Angie Park, Steven Cwirla, Alice Bakker, Ronald Barrett, Michael Needels, Praechompoo Pongtornpipat, Blake Williams, Prarthana Joshi, William Dower

Publikováno v: Regular and Young Investigator Award Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c697c05d9490076cfac215a2e0d83208
https://doi.org/10.1136/jitc-2022-sitc2022.1097

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