Treatment and prevention strategies for the COVID 19 pandemic: A review of immunotherapeutic approaches for neutralizing SARS-CoV-2

Autor: Michael N.G. James, Jiang Yin, Pravas Kumar Baral

Publikováno v: International Journal of Biological Macromolecules

Researchers from the world over are working to create prophylactic and therapeutic interventions to combat the COVID-19 global healthcare crisis. The current therapeutic options against the COVID-19 include repurposed drugs aimed at targets other tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664f701c247b9443587838ffc7155a7d
https://doi.org/10.1016/j.ijbiomac.2021.07.013

Contributors

Autor: Bekhzod Abdullaev, Mohammad Afzal, Faizan Ahmad, Javed Ahmad, Manzar Alam, Sabeeha Ali, Narendran Annadurai, Saleha Anwar, Shabnam Anjum Ara, Sufian Badar, Soghra Bagheri, Subhamoy Banerjee, Eijaz Ahmed Bhat, Hardik Bhatt, Deepa Bisht, Siddhartha Dan, Debasis Das, Viswanath Das, Poonam Dhankhar, Divya Dube, Parth Gupta, Varsha Gupta, Md. Imtaiyaz Hassan, Azadeh Hekmat, Zeeshan Hyderi, Asimul Islam, Michael N.G. James, Hem Chandra Jha, Bimal Prasad Jit, Dharmendra Kashyap, Lajpreet Kaur, Md Khurshid Alam Khan, Mohammad Ahmed Khan, Dhiraj Kumar, Pravindra Kumar, Vinod Kumar, Varsha Kumari, Parul Mishra, Ashish Misra, Disha Mittal, Pooja Mittal, Taj Mohammad, Syed Shahid Musvi, Garima Nagar, Asma Naqi, Chirasmita Nayak, Karishma Niveria, Saba Noor, Himanshu Ojha, Amrita Arpita Padhy, Mallika Pathak, Upasana Pathak, Roshani Payoe, Sandhya Rai, Annu Rani, Sourbh Rankawat, Rajnikant Raut, Ali Raza, Vanshika Rustagi, Ali Akbar Saboury, Manisha Sachan, Subhashree Sahoo, Taruna Saini, Nasreena Sajjad, Ilma Shakeel, Anas Shamsi, Tooba Naz Shamsi, Saroj Sharma, Suman Shaw, Kummari Shivani, Archana Singh, Indrakant Kumar Singh, Sanjeev Kumar Singh, Vishakha Singh, Rahul Singhal, Ankit Srivastava, Sameer Srivastava, Deeksha Tiwari, Vishvanath Tiwari, Nidhi Varshney, Anita Kamra Verma, Keerti Vishwakarma, Yeshfa Zaidi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4051508f836f3e0ea144929d985e58a2
https://doi.org/10.1016/b978-0-323-91287-7.09991-9

Transition of the prion protein from a structured cellular form (PrP C ) to the infectious scrapie agent (PrP Sc )

Autor: Michael N.G. James, Pravas Kumar Baral, Adriano Aguzzi, Jiang Yin

Publikováno v: Protein Sci

Prion diseases in mammals are caused by a conformational transition of the cellular prion protein from its native conformation (PrP(C)) to a pathological isoform called “prion protein scrapie” (PrP(Sc)). A molecular level of understanding of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503f46cbbfa513b58d7bbab899fe33cd
https://doi.org/10.1002/pro.3735

Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion

Autor: Adriano Aguzzi, Pravas Kumar Baral, Michael N.G. James, Mridula Swayampakula

Publikováno v: The FEBS journal. 285(9)

Conversion of the cellular prion protein PrPC into its pathogenic isoform PrPSc is the hallmark of prion diseases, fatal neurodegenerative diseases affecting many mammalian species including humans. Anti‐prion monoclonal antibodies can arrest the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d6d3126fedff0b555a0ca28fc3de1e
https://pubmed.ncbi.nlm.nih.gov/29569342

Insights into Mucopolysaccharidosis I from the structure and action of α-L-Iduronidase

Autor: Haiying Bie, Ethan D. Goddard-Borger, Jiang Yin, Allison R. Kermode, Stephen G. Withers, Xu He, Michael N.G. James

Publikováno v: Nature chemical biology

Mucopolysaccharidosis type I (MPS I), caused by mutations in the gene encoding α-L-iduronidase (IDUA), is one of approximately 70 genetic disorders collectively known as the lysosomal storage diseases. To gain insight into the basis for MPS I, we ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0bb3719b6e1f0ce31bd82810dec78f6
http://europepmc.org/articles/PMC4954775