Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Michael N. Starnbach"'
Autor:
Joseph S. Park, Jennifer D. Helble, Jacob E. Lazarus, Guanhua Yang, Carlos J. Blondel, John G. Doench, Michael N. Starnbach, Matthew K. Waldor
Publikováno v:
iScience, Vol 11, Iss , Pp 71-84 (2019)
Summary: The invasion of Chlamydia trachomatis, an obligate intracellular bacterium, into epithelial cells is driven by a complex interplay of host and bacterial factors. To comprehensively define the host genes required for pathogen invasion, we und
Externí odkaz:
https://doaj.org/article/aeb8a890a61a468d863b75026b321f07
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT While there is no effective vaccine against Chlamydia trachomatis infection, previous work has demonstrated the importance of C. trachomatis-specific CD4+ T cells (NR1 T cells) in pathogen clearance. Specifically, NR1 T cells have been shown
Externí odkaz:
https://doaj.org/article/83235d1ecf374b60ba5b9da3421c92fe
Autor:
Yoelys Cruz-Leal, Daniel Grubaugh, Catarina V. Nogueira, Isbel Lopetegui-González, Anaixis del Valle, Felipe Escalona, Rady J. Laborde, Carlos Alvarez, Luis E. Fernández, Michael N. Starnbach, Darren E. Higgins, María E. Lanio
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Cross-presentation is an important mechanism for the differentiation of effector cytotoxic T lymphocytes (CTL) from naïve CD8+ T-cells, a key response for the clearance of intracellular pathogens and tumors. The liposomal co-encapsulation of the por
Externí odkaz:
https://doaj.org/article/5a034972a0854573bde313803249050a
Publikováno v:
PLoS pathogens. 18(10)
The Lyme disease bacterial pathogen,Borrelia burgdorferi, establishes a long-term infection inside its mammalian hosts. Despite the continued presence of the bacteria in animal models of disease, inflammation is transitory and resolves spontaneously.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1221bad6d7dd98d248d447f98b737a8
https://pubmed.ncbi.nlm.nih.gov/36265003
https://pubmed.ncbi.nlm.nih.gov/36265003
Autor:
Catarina V. Nogueira, Rady J. Laborde, Yoelys Cruz-Leal, M. C. Luzardo, Darren E. Higgins, Lianne Abreu-Butin, Daniel Grubaugh, Audry Fernández, Ieda Maria Longo-Maugéri, Circe Mesa, Fabiola Pazos, María E. Lanio, Luis E. Fernández, Michael N. Starnbach, Mayari Eika Ishimura, Carlos Alvarez, María E. Alonso
Publikováno v:
Molecular Immunology. 131:144-154
Sticholysins (Sts) I and II (StI and StII) are pore-forming proteins (PFPs), purified from the Caribbean Sea anemone Stichodactyla helianthus. StII encapsulated into liposomes induces a robust antigen-specific cytotoxic CD8+ T lymphocytes (CTL) respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc6e326aff264a56b8da67d237bc4da
https://doi.org/10.1016/j.molimm.2020.12.032
https://doi.org/10.1016/j.molimm.2020.12.032
Autor:
Michael N. Starnbach
Publikováno v:
Current Opinion in Microbiology. 54:33-36
Stan Falkow looked at the world with his eyes peering from the outer membrane of a gram-negative bacterium. It was a great vantage point from which to dream about the possible superpowers these organisms might have. He mused about these dreams with h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1012a16ad987da494c10220bdbe76403
https://doi.org/10.1016/j.mib.2020.01.004
https://doi.org/10.1016/j.mib.2020.01.004
Autor:
Jacob E. Lazarus, Guanhua Yang, Carlos J. Blondel, Joseph Park, Jennifer D. Helble, John G. Doench, Michael N. Starnbach, Matthew K. Waldor
Publikováno v:
iScience, Vol 11, Iss, Pp 71-84 (2019)
iScience
iScience
Summary The invasion of Chlamydia trachomatis, an obligate intracellular bacterium, into epithelial cells is driven by a complex interplay of host and bacterial factors. To comprehensively define the host genes required for pathogen invasion, we unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4465c3570b56dde556c398c75b208395
http://www.sciencedirect.com/science/article/pii/S2589004218302402
http://www.sciencedirect.com/science/article/pii/S2589004218302402
Publikováno v:
Pathog Dis
Chlamydia trachomatis is the most commonly reported sexually transmitted infection in the United States. The high prevalence of infection and lack of a vaccine indicate a critical knowledge gap surrounding the host's response to infection and how to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abf341b76d60ce30b6e2655feb75e49
https://pubmed.ncbi.nlm.nih.gov/33693620
https://pubmed.ncbi.nlm.nih.gov/33693620
Publikováno v:
The Journal of Immunology. 208:170.19-170.19
Borrelia burgdorferi, the causative agent of Lyme disease, establishes a long-term infection inside its mammalian hosts. Despite the continued presence of the bacteria in animal models of disease, inflammation is transitory and resolves spontaneously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ecfc7cfb9f9c2d18962eb7218e4535a
https://doi.org/10.4049/jimmunol.208.supp.170.19
https://doi.org/10.4049/jimmunol.208.supp.170.19
Publikováno v:
mBio, Vol 11, Iss 2, p e00191-20 (2020)
mBio, Vol 11, Iss 2 (2020)
mBio
mBio, Vol 11, Iss 2 (2020)
mBio
Chlamydia trachomatis is an important mucosal pathogen that is the leading cause of sexually transmitted bacterial infections in the United States. Despite this, there is no vaccine currently available. In order to develop such a vaccine, it is neces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea61a036b3fda13c7dcf36794ca09faf
https://doaj.org/article/734392fc505d4901856e114927620e51
https://doaj.org/article/734392fc505d4901856e114927620e51