Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Michael N. Sayegh"'
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Akademický článek
Chest Pain in Women: Gender- and Sex-based Differences in the Presentation and Diagnosis of Heart Disease
Autor: Mariem A Sawan, Rebecca S Steinberg, Michael N Sayegh, Christian Devlin, Omid Behbahani-Nejad, Nanette K Wenger
Publikováno v: US Cardiology Review, Vol 17, Iss , Pp - (2023)
Ischemic heart disease is a major cause of morbidity and mortality in the US, affecting both men and women significantly. The presentation of chest pain is largely similar in female and male patients, but additional non-chest pain symptoms can confou
Externí odkaz: https://doaj.org/article/fb77dc444a7e4fcc91af14fe0b45287a
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4
A Hydrogel Strategy to Augment Tissue Adenosine to Improve Hindlimb Perfusion
Autor: Woojin M. Han, Frederick Strobel, Kimberly A. Cooney, Rebecca D. Levit, Lanfang Wang, Andrés J. García, Laura Hansen, Michael N. Sayegh
Publikováno v: Arterioscler Thromb Vasc Biol
Objective: Adenosine is an important vasodilatory, anti-inflammatory, and antithrombotic agent; however, its delivery for the treatment of cardiovascular diseases is challenging due to the drug’s short half-life and dose-limiting side effects. Peri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d39d5c5974b4808f33dcb24474172f3
https://doi.org/10.1161/atvbaha.120.315428
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6
Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques
Autor: Zachary Strongin, Timothy N. Hoang, Rebecca D. Levit, Shelly Wang, Sherrie Jean, Kimberly A. Cooney, Susan Pereira Ribeiro, Mirko Paiardini, Lanfang Wang, Gregory K. Tharp, Rafick Pierre Sekaly, Michael Nekorchuk, Elise G. Viox, Raymond F. Schinazi, Justin L. Harper, Jacob D. Estes, Steven E. Bosinger, Michelle Y.H. Lee, Hilmi Al-Shakhshir, Rachelle L. Stammen, Kathleen Busman-Sahay, Arun K. Boddapati, Daniela Weiskopf, Sijia Tao, Anne Piantadosi, Guido Silvestri, Kathryn L. Pellegrini, Maria Pino, Michael N. Sayegh, Fawn Connor-Stroud, Thomas H. Vanderford, Tristan R. Horton, Jesse J. Waggoner, Joyce Cohen, Olivia M. Delmas, Jennifer S. Wood, Peter D. Filev, Carly E. Starke, Amit A. Upadhyay, Sudhir Pai Kasturi, Ernestine A. Mahar, Shannon Kirejczyk, Elizabeth N. Beagle, Sanjeev Gumber, Keivan Zandi
Publikováno v: bioRxiv
article-version (status) pre
article-version (number) 1
Cell
SARS-CoV-2 induced hypercytokinemia and inflammation are critically associated with COVID-19 disease severity. Baricitinib, a clinically approved JAK1/2 inhibitor, is currently being investigated in COVID-19 clinical trials. Here, we investigated the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4714908327d21cfa2db754cec36a91
https://pubmed.ncbi.nlm.nih.gov/32995780
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7
Multi-parametric cell profiling with a CMOS quad-modality cellular interfacing array for label-free fully automated drug screening
Autor: Taiyun Chi, Moez Karim Aziz, Jong Seok Park, Adam Wang, Sensen Li, Hua Wang, Sandra I. Grijalva, Michael N. Sayegh, Hee Cheol Cho
Publikováno v: Lab on a Chip, 18 (19)
Lab on a chip
Cells are complex systems with concurrent multi-physical responses, and cell physiological signals are often encoded with spatiotemporal dynamics and further coupled with multiple cellular activities. However, most existing electronic sensors are onl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3cc4ef4879ebb9927c68710105a2a3e
https://doi.org/10.1039/c8lc00156a
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Procedural outcomes and long-term survival following lead extraction in octogenarians
Autor: Yaanik Desai, Adarsh Patel, Faisal M. Merchant, Michael N. Sayegh, Mikhael F. El-Chami, Jad El-Khalil, Angel R. Leon
Publikováno v: Pacing and Clinical Electrophysiology. 40:868-872
BACKGROUND Octogenarians account for a significant percentage of patients with indwelling pacemakers or defibrillators. OBJECTIVES To determine procedural outcomes and long-term survival after lead extraction (LE) in octogenarians. METHODS We retrosp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::619b0812f4e2d0dbf7c26b075274a51f
https://doi.org/10.1111/pace.13113
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Outcomes of lead extraction in young adults
Autor: Mikhael F. El-Chami, Adarsh Patel, Yaanik Desai, Faisal M. Merchant, Michael N. Sayegh, Jad El-Khalil, Angel R. Leon
Publikováno v: Heart Rhythm. 14:537-540
Extraction of pacemaker and defibrillator leads in young adults may be technically challenging because of more extensive fibrosis and calcification in this patient population.The purpose of this study was to examine outcomes of lead extraction (LE) i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9bb9dfe6c7b80b35726a1dd35723145
https://doi.org/10.1016/j.hrthm.2017.01.030
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Abstract 146: Investigating and Inhibiting Neutrophil Extracellular Trap Formation in the Heart
Autor: Michael N. Sayegh, Eric Shin, Milton E. Brown, Woojin M. Han, Lanfang Wang, Andrés J. García, Rebecca D. Levit, Michael Davis
Publikováno v: Circulation Research. 125
Neutrophil extracellular traps (NETs) have been observed in multiple diseases of the cardiovascular system, such as myocardial infarction and atherosclerosis. We have recently shown that adenosine (ADO) inhibits NET formation and may be an important
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36172c528b6d1c51bf950fb730e8fdcb
https://doi.org/10.1161/res.125.suppl_1.146
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