Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael N. Rutherford"'
Autor:
Michael N. Rutherford, David P. LeBrun
Publikováno v:
The American Journal of Pathology. 153:165-173
E2A is a basic helix-loop-helix (bHLH) transcription factor required for B cell lymphopoiesis and implicated in myogenesis and the regulation of insulin expression. As E2A is expressed widely in tissues, tissue-specific downstream effects are thought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd1e684c42fc19d4a85a9ec2cd04db8
https://doi.org/10.1016/s0002-9440(10)65557-5
https://doi.org/10.1016/s0002-9440(10)65557-5
Publikováno v:
Journal of Interferon & Cytokine Research. 17:1-10
Interferon (IFN) activation of genes bearing an IFN-stimulated response element (ISRE) is regulated through binding of IFN-stimulated gene factors (ISGF) to the ISRE found in many IFN-stimulated genes. Using a multimerized human 2-5A synthetase ISRE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ffd744c45314c35af8a7497d2c0856
https://doi.org/10.1089/jir.1997.17.1
https://doi.org/10.1089/jir.1997.17.1
Autor:
Bryan R.G. Williams, Aseem Kumar, D. Skup, Michael N. Rutherford, David H. Carver, Benoit Coulombe
Publikováno v:
Journal of Interferon & Cytokine Research. 16:507-510
The mechanism(s) by which interferon (IFN)-alpha confers resistance to viruses is currently being characterized. Previous studies have shown that binding of IFN-alpha to its high-affinity receptor activates transcription factor interferon-stimulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5ca81e518ae84e6f748890078df108
https://doi.org/10.1089/jir.1996.16.507
https://doi.org/10.1089/jir.1996.16.507
Publikováno v:
European journal of biochemistry. 219(1-2)
A clone of interferon-alpha-resistant (IFNr) Daudi cells retained much greater transcriptional inducibility of the (2'-5') oligoadenylate synthetase than the 6-16 gene despite the fact that the response of both genes is mediated by highly similar int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4059bd5776d3a4d791fe42b24d9429f
https://pubmed.ncbi.nlm.nih.gov/8307020
https://pubmed.ncbi.nlm.nih.gov/8307020
Publikováno v:
Journal of Virology. 62:3077-3083
In vivo responses to interferon (IFN) in mice were determined by measuring the steady-state levels of induced mRNAs following injection of IFN and poly(I)-poly(C). With cDNA probes for mouse 2'-5' oligoadenylate synthetase (2-5A synthetase) and 1-8,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f157934479a7b77b6bdc801b58bc24
https://doi.org/10.1128/jvi.62.9.3077-3083.1988
https://doi.org/10.1128/jvi.62.9.3077-3083.1988
Publikováno v:
Journal of Cellular Biochemistry. 38:261-267
We assayed fragments of the 5' flanking sequence of the human 2-5A synthetase gene for their ability to respond to interferon-alpha (IFN) and platelet-derived growth factor (PDGF). Transient transfection assays identified a 40-base pair fragment, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0f0c853ce9da491858c7fc851949e4
https://doi.org/10.1002/jcb.240380405
https://doi.org/10.1002/jcb.240380405