Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Michael N Starnbach"'
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010903 (2022)
The Lyme disease bacterial pathogen, Borrelia burgdorferi, establishes a long-term infection inside its mammalian hosts. Despite the continued presence of the bacteria in animal models of disease, inflammation is transitory and resolves spontaneously
Externí odkaz:
https://doaj.org/article/5d1d8fee4755451584600a6702739c89
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240670 (2020)
Memory antigen-specific CD4+ T cells against Chlamydia trachomatis are necessary for protection against secondary genital tract infection. While it is known that naïve antigen-specific CD4+ T cells can traffic to the genital tract in an antigen-spec
Externí odkaz:
https://doaj.org/article/3b25f297cf5f4b73be85007f4f1f8616
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8, p e1002809 (2012)
The activation of host cells by interferon gamma (IFNγ) is essential for inhibiting the intracellular replication of most microbial pathogens. Although significant advances have been made in identifying IFNγ-dependent host factors that suppress int
Externí odkaz:
https://doaj.org/article/576e161bf9af407f9cc7d9e71c27b6cc
Autor:
Jörn Coers, Dave C Gondek, Andrew J Olive, Amy Rohlfing, Gregory A Taylor, Michael N Starnbach
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1001346 (2011)
The obligate intracellular pathogen Chlamydia trachomatis is the most common cause of bacterial sexually transmitted diseases in the United States. In women C. trachomatis can establish persistent genital infections that lead to pelvic inflammatory d
Externí odkaz:
https://doaj.org/article/3275b5c7c92a48e397d2219541c49459
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27662 (2011)
The presence of a complex and diverse intestinal flora is functionally important for regulating intestinal mucosal immune responses. However, the extent to which a balanced intestinal flora regulates systemic immune responses is still being defined.
Externí odkaz:
https://doaj.org/article/3515e7c3a39b4cfbb030daea31520781
Publikováno v:
PLoS Pathogens, Vol 5, Iss 9, p e1000573 (2009)
All Yersinia species target and bind to phagocytic cells, but uptake and destruction of bacteria are prevented by injection of anti-phagocytic Yop proteins into the host cell. Here we provide evidence that CD8(+) T cells, which canonically eliminate
Externí odkaz:
https://doaj.org/article/b3b7cce9a45946b2a946b54a0d9e518d
Modeling infectious disease in mice: co-adaptation and the role of host-specific IFNgamma responses.
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000333 (2009)
Externí odkaz:
https://doaj.org/article/3ce4e975a2024595ad686d8e81470e68
Autor:
Roger W Kramer, Naomi L Slagowski, Ngozi A Eze, Kara S Giddings, Monica F Morrison, Keri A Siggers, Michael N Starnbach, Cammie F Lesser
Publikováno v:
PLoS Pathogens, Vol 3, Iss 2, p e21 (2007)
Numerous bacterial pathogens manipulate host cell processes to promote infection and ultimately cause disease through the action of proteins that they directly inject into host cells. Identification of the targets and molecular mechanisms of action u
Externí odkaz:
https://doaj.org/article/6161d082b9b940b2aa8b4f83a6c05b6b
Autor:
Catarina V. Nogueira, Rady J. Laborde, Yoelys Cruz-Leal, M. C. Luzardo, Darren E. Higgins, Lianne Abreu-Butin, Daniel Grubaugh, Audry Fernández, Ieda Maria Longo-Maugéri, Circe Mesa, Fabiola Pazos, María E. Lanio, Luis E. Fernández, Michael N. Starnbach, Mayari Eika Ishimura, Carlos Alvarez, María E. Alonso
Publikováno v:
Molecular Immunology. 131:144-154
Sticholysins (Sts) I and II (StI and StII) are pore-forming proteins (PFPs), purified from the Caribbean Sea anemone Stichodactyla helianthus. StII encapsulated into liposomes induces a robust antigen-specific cytotoxic CD8+ T lymphocytes (CTL) respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc6e326aff264a56b8da67d237bc4da
https://doi.org/10.1016/j.molimm.2020.12.032
https://doi.org/10.1016/j.molimm.2020.12.032
Autor:
Michael N. Starnbach
Publikováno v:
Current Opinion in Microbiology. 54:33-36
Stan Falkow looked at the world with his eyes peering from the outer membrane of a gram-negative bacterium. It was a great vantage point from which to dream about the possible superpowers these organisms might have. He mused about these dreams with h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1012a16ad987da494c10220bdbe76403
https://doi.org/10.1016/j.mib.2020.01.004
https://doi.org/10.1016/j.mib.2020.01.004