Effects of niacin and omega-3 fatty acids on HDL-apolipoprotein A-I exchange in subjects with metabolic syndrome.

Autor: Mark S Borja, Bradley Hammerson, Chongren Tang, Litzy Juarez-Serrano, Olga V Savinova, William S Harris, Michael N Oda, Gregory C Shearer

Publikováno v: PLoS ONE, Vol 19, Iss 2, p e0296052 (2024)

HDL-apolipoprotein A-I exchange (HAE) measures a functional property associated with HDL's ability to mediate reverse cholesterol transport. HAE has been used to examine HDL function in case-control studies but not in studies of therapeutics that alt

Externí odkaz: https://doaj.org/article/0f4352c25d7f41779380cbd0db1e19f6

HDL-apoA-I exchange: rapid detection and association with atherosclerosis.

Autor: Mark S Borja, Lei Zhao, Bradley Hammerson, Chongren Tang, Richard Yang, Nancy Carson, Gayani Fernando, Xiaoqin Liu, Madhu S Budamagunta, Jacques Genest, Gregory C Shearer, Franck Duclos, Michael N Oda

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e71541 (2013)

High density lipoprotein (HDL) cholesterol levels are associated with decreased risk of cardiovascular disease, but not all HDL are functionally equivalent. A primary determinant of HDL functional status is the conformational adaptability of its main

Externí odkaz: https://doaj.org/article/1e58836a5d004ecdb31766e8e2e6b96a

High-density lipoprotein function is associated with atherosclerotic burden and cardiovascular outcomes in type 2 diabetes

Autor: Anne Pernille Ofstad, Cathrine Brunborg, Kåre I. Birkeland, Odd Erik Johansen, Lars Gullestad, Martin Heier, Mark S. Borja, Knut Endresen, Michael N. Oda

Publikováno v: Atherosclerosis. 282:183-187

Background and aims Measures of HDL function are emerging tools for assessing cardiovascular disease (CVD) event risk. HDL-apoA-I exchange (HAE) reflects HDL capacity for reverse cholesterol transport. Methods HAE was measured in 93 participants with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f537b88bf367b7fa79d6e1b76b0e28
https://doi.org/10.1016/j.atherosclerosis.2018.07.005

Modification by isolevuglandins, highly reactive γ-ketoaldehydes, deleteriously alters high-density lipoprotein structure and function

Autor: MacRae F. Linton, Michael N. Oda, Jiansheng Huang, Mark S. Borja, Sean S. Davies, W. Gray Jerome, Linda S. May-Zhang, Valery Yermalitsky, Patricia G. Yancey, Tiffany Pleasent

Publikováno v: Journal of Biological Chemistry. 293:9176-9187

Cardiovascular disease risk depends on high-density lipoprotein (HDL) function, not HDL-cholesterol. Isolevuglandins (IsoLGs) are lipid dicarbonyls that react with lysine residues of proteins and phosphatidylethanolamine. IsoLG adducts are elevated i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add996d114ef23bf5dc81d38d8a50c02
https://doi.org/10.1074/jbc.ra117.001099

Dysfunctional high-density lipoprotein from HIV+ individuals promotes monocyte-derived foam cell formation in vitro

Autor: Theodoros Kelesidis, Thomas A Angelovich, Mark S. Borja, Anthony Jaworowski, Diana Huynh, Anna C. Hearps, Michael N. Oda, Stefanie Homann

Publikováno v: AIDS (London, England), vol 31, iss 17
Angelovich, TA; Hearps, AC; Oda, MN; Borja, MS; Huynh, D; Homann, S; et al.(2017). Dysfunctional high-density lipoprotein from HIV+ individuals promotes monocyte-derived foam cell formation in vitro. AIDS, 31(17), 2331-2336. doi: 10.1097/QAD.0000000000001642. UCLA: Retrieved from: http://www.escholarship.org/uc/item/1rp9m168

ObjectiveThe role of high-density lipoprotein (HDL) function in HIV-related atherosclerotic cardiovascular disease (CVD) is unclear. HDLs isolated from HIV [HIV(+)HDL] and HIV-uninfected individuals [HIV(-)HDL] were assessed for HDL function and abil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484cedbb9c61b8de07615ebff87a9c44
https://doi.org/10.1097/qad.0000000000001642