Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Michael Nüsse"'
Publikováno v:
Antiquity. 82:423-437
Thanks to a number of well-stratified sequences, the authors can offer a new history of clay image-making in West Africa. From the first known human occupation in the second millennium BC, the shaped clay figurines remain remarkably conservative, sug
Autor:
Luca Sangiorgi, Silvia Capponcelli, Carmela Fimognari, Giorgio Cantelli-Forti, Fausto Berti, Michael Nüsse, Silvia Soddu, Patrizia Hrelia, Silvia Fontanesi
Publikováno v:
Investigational New Drugs. 23:195-203
We investigated apoptosis induction by sulforaphane on three cell lines characterized by a different p53 status. In particular, we used p53-knock-out fibroblasts from newborn mice transfected with the p53-Ser220 mutation, observed in Li-Fraumeni Synd
Publikováno v:
Chemotherapy. 51:332-335
Background: Little is currently known regarding the cancer-preventive potential of cyanidin-3-O-β-glucopyranoside (Cy-g) apart from its antioxidant activity. Methods: We tested Cy-g on Jurkat and HL-60 leukemia cell lines and, to help elucidate whet
Publikováno v:
Biochemical Pharmacology. 67:2047-2056
Little is known about the potentially chemopreventive mechanisms of anthocyanins apart from their antioxidant activity. We investigated the in vitro capacity of the anthocyanin cyanidin-3-O-beta-glucopyranoside (Cy-g) to induce apoptosis in T-lymphob
Autor:
Fausto Berti, Patrizia Hrelia, Michael Nüsse, Giorgio Cantelli-Forti, Renato Iori, Carmela Fimognari
Publikováno v:
Annals of the New York Academy of Sciences. 1010:393-398
Isothiocyanates exert chemopreventive effects against chemically induced tumors in animals, modulating enzymes required for carcinogens' activation/detoxification and/or the induction of cell-cycle arrest and apoptosis in tumor cell lines. To investi
Autor:
Patrizia Hrelia, Fausto Berti, Renato Iori, Giorgio Cantelli-Forti, Carmela Fimognari, Michael Nüsse
Publikováno v:
Cellular and Molecular Life Sciences. 59:2004-2012
Despite experimental evidence that sulforaphane can exert chemopreventive effects, whether these effects are specific for neoplastic cells is not known. Following our previous demonstration that sulforaphane induces cell cycle arrest and apoptosis in
Autor:
Michael Nüsse, Giorgio Cantelli-Forti, Carmela Fimognari, Renato Iori, Patrizia Hrelia, Rossano Cesari
Publikováno v:
Scopus-Elsevier
Carcinogenesis 23, 581-586 (2002)
Carcinogenesis 23, 581-586 (2002)
Glucosinolates (GL) can inhibit, retard or reverse experimental multistage carcinogenesis. When brassica plant tissue is broken, GLs are hydrolyzed by the endogenous enzyme myrosinase (Myr), releasing many products including isothiocyanates (ITC). Sy
Autor:
Michael Nüsse, Kristin Marx, Werner Grundler, Andreas Stampfl, Konrad Maier, Wolfgang Beisker, Peter Dirscherl, Ingrid Zimmermann
Publikováno v:
Cytometry. 44:45-56
Background Programmed cell death, also termed apoptosis, is the main focus of interest in a variety of scientific and clinical areas. For a better understanding of the mechanisms of apoptosis, from the onset of the cellular death program to the late
Publikováno v:
Pharmacological Research. 41:385-390
Publikováno v:
Cytometry. 37:221-229
Background: The detection of DNA-incorporated bromodeoxyuridine (BrdUrd) in mammalian cells is a well-known and important technique to study cell cycle. The use of TO-PRO-3 for detection of BrdUrd substitution of DNA by dual-laser flow cytometry has