Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michael Murrell"'
Autor:
Ida Ang, Muhammad Sulaiman Yousafzai, Vikrant Yadav, Kyle Mohler, Jesse Rinehart, Nikolaos Bouklas, Michael Murrell
Publikováno v:
APL Bioengineering, Vol 8, Iss 2, Pp 026109-026109-13 (2024)
During cancer pathogenesis, cell-generated mechanical stresses lead to dramatic alterations in the mechanical and organizational properties of the extracellular matrix (ECM). To date, contraction of the ECM is largely attributed to local mechanical s
Externí odkaz:
https://doaj.org/article/a0317bb3a9af4c7a9eca9eda5ce83f5c
Autor:
Sorosh Amiri, Camelia Muresan, Xingbo Shang, Clotilde Huet-Calderwood, Martin A. Schwartz, David A. Calderwood, Michael Murrell
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The filamentous actin (F-actin) cytoskeleton is a composite material consisting of cortical actin and bundled F-actin stress fibers, which together mediate the mechanical behaviors of the cell, from cell division to cell migration. However,
Externí odkaz:
https://doaj.org/article/ce14d1660c824adbb36e86e71d1ace82
Autor:
Zachary Gao Sun, Vikrant Yadav, Sorosh Amiri, Wenxiang Cao, Enrique M. De La Cruz, Michael Murrell
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 1, Pp 151379- (2024)
The organization of actin filaments (F-actin) into crosslinked networks determines the transmission of mechanical stresses within the cytoskeleton and subsequent changes in cell and tissue shape. Principally mediated by proteins such as α-actinin, F
Externí odkaz:
https://doaj.org/article/07517b2f4f854a6bb922ac8321294967
Autor:
Muhammad Sulaiman Yousafzai, Vikrant Yadav, Sorosh Amiri, Michael F. Staddon, Youssef Errami, Gwilherm Jaspard, Shiladitya Banerjee, Michael Murrell
Publikováno v:
Physical Review X, Vol 12, Iss 3, p 031027 (2022)
The magnitude of mechanical stresses caused by cell surface tension may be comparable to the bulk elasticity of their matrix on cellular length scales, yet how capillary effects influence tissue shape and motion are unknown. In this work, we induce w
Externí odkaz:
https://doaj.org/article/e217f7ab0e3a4a7c8790f382fd92dde8
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24283 (2011)
We use a novel, microfluidics-based technique to deconstruct the classical wound healing scratch assay, decoupling the contribution of free space and cell damage on the migratory dynamics of an epithelial sheet. This method utilizes multiple laminar
Externí odkaz:
https://doaj.org/article/920ec1af9b5745398f764ad9e6d94e0a
Autor:
Merav Socolovsky, Michael Murrell, Ying Liu, Ramona Pop, Ermelinda Porpiglia, Andre Levchenko
Publikováno v:
PLoS Biology, Vol 5, Iss 10, p e252 (2007)
Tissue development is regulated by signaling networks that control developmental rate and determine ultimate tissue mass. Here we present a novel computational algorithm used to identify regulatory feedback and feedforward interactions between progen
Externí odkaz:
https://doaj.org/article/e16353b3e567477584809f74186d4946
Autor:
Vikrant Yadav, Md. Sulaiman Yousafzai, Sorosh Amiri, Robert W. Style, Eric R. Dufresne, Michael Murrell
Publikováno v:
Physical Review Fluids. 7
The surface tension of living cells and tissues originates from the generation of nonequilibrium active stresses within the cell cytoskeleton. Here, using laser ablation, we generate gradients in the surface tension of cellular aggregates as models o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef7bf870ecb2bb395a4dcdfb7638881
https://doi.org/10.1103/physrevfluids.7.l031101
https://doi.org/10.1103/physrevfluids.7.l031101
Autor:
Sung Hoon Lee, Jay C. Hou, Archer Hamidzadeh, M. Sulaiman Yousafzai, Visar Ajeti, Hao Chang, David J. Odde, Michael Murrell, Andre Levchenko
Publikováno v:
Cell systems. 13(7)
Navigation through a dense, physically confining extracellular matrix is common in invasive cell spread and tissue reorganization but is still poorly understood. Here, we show that this migration is mediated by cyclic changes in the activity of a sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547f493e6e197a13283bac408db69c0d
https://pubmed.ncbi.nlm.nih.gov/35679858
https://pubmed.ncbi.nlm.nih.gov/35679858
Autor:
Teh-Lung Ku, Michael Murrell
The main goal of the research is to understand the migratory behavior of radioactive contaminants in subsurface fractured systems by using naturally occurring U-series radionuclides as tracers under in-situ physico-chemical and hydrogeologic conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26cab87479228896697deb276257ad15
https://doi.org/10.2172/827117
https://doi.org/10.2172/827117
