Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michael Munroe"'
Autor:
Hae R Chung, Mayand Vakil, Michael Munroe, Alay Parikh, Benjamin M Meador, Pei T Wu, Jin H Jeong, Jeffrey A Woods, Kenneth R Wilund, Marni D Boppart
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168065 (2016)
HMG-CoA reductase inhibitors (statins) are the most effective pharmacological means of reducing cardiovascular disease risk. The most common side effect of statin use is skeletal muscle myopathy, which may be exacerbated by exercise. Hypercholesterol
Externí odkaz:
https://doaj.org/article/a972d114c9a444e9a863c5ca607f4e92
Autor:
Jenny Drnevich, Charlotte Coombs, Garret Waterstradt, Koyal Garg, Brent Blackwell, Michael Munroe, Yair Pincu, Ziad S. Mahmassani, Justin S. Rhodes, Isaac Lee, Svyatoslav Dvoretskiy, Marni D. Boppart, Gabriela Garcia
Publikováno v:
Am J Physiol Cell Physiol
Unaccustomed resistance exercise can initiate skeletal muscle remodeling and adaptive mechanisms that can confer protection from damage and enhanced strength with subsequent stimulation. The myofiber may provide the primary origin for adaptation, yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11527a89c5180d36c7605a42c60544a0
https://doi.org/10.1152/ajpcell.00156.2019
https://doi.org/10.1152/ajpcell.00156.2019
Autor:
Annabel Quinet, Enzo Tedone, Tianpeng Zhang, Michael Munroe, Ho-Chang Jeong, Luis F.Z. Batista, Alessandro Vindigni, Roger A. Greenberg, Alexandre T. Vessoni, Jerry W. Shay, Matthew D. Wood
Publikováno v:
The Journal of Cell Biology
Vessoni et al. demonstrate telomere shortening leads to a unique DDR response in human pluripotent stem cells. Unlike terminally differentiated cells, telomere shortening induces formation of single-stranded DNA telomere overhangs in hPSCs, which act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502021f1e2e45a99cb8eaa186b6b03d7
https://doi.org/10.1083/jcb.202011014
https://doi.org/10.1083/jcb.202011014
Publikováno v:
Stem Cell Biology and Regenerative Medicine ISBN: 9783030621285
Skeletal muscle structure and function are dependent on the presence or absence of mechanical cues in the tissue microenvironment. High intensity or sustained contractions can build muscle mass with exercise training, whereas bedrest or limb immobili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a549feb99e3b31231fa2fa9deecfbe23
https://doi.org/10.1007/978-3-030-62129-2_9
https://doi.org/10.1007/978-3-030-62129-2_9
Autor:
Ho-Chang Jeong, Kirsten Ann Brenner, Evandro Luís de Oliveira Niero, Alexandre T. Vessoni, Wilson C. Fok, Michael Munroe, Luis F.Z. Batista
Publikováno v:
Hepatology (Baltimore, Md.)
Background and aims Telomere attrition is a major risk factor for end-stage liver disease. Due to a lack of adequate models and intrinsic difficulties in studying telomerase in physiologically relevant cells, the molecular mechanisms responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa9b9371fa182d91774449b0d1d7c92
https://pubmed.ncbi.nlm.nih.gov/32632978
https://pubmed.ncbi.nlm.nih.gov/32632978
Autor:
Yair Pincu, Jie Chen, Kook Son, Jenny Drnevich, Ziad S. Mahmassani, Marni D. Boppart, Michael Munroe
Publikováno v:
American Journal of Physiology-Cell Physiology. 312:C638-C650
The α7β1integrin is concentrated at the costameres of skeletal muscle and provides a critical link between the actin cytoskeleton and laminin in the basement membrane. We previously demonstrated that expression of the α7BX2 integrin subunit (MCK:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16792e79a8f8eec0116dc008bb7161f7
https://doi.org/10.1152/ajpcell.00106.2016
https://doi.org/10.1152/ajpcell.00106.2016
Autor:
Tor W. Jensen, Adam Cobert, Ryan Brander, Michael Munroe, Marni D. Boppart, Yair Pincu, Justin S. Rhodes, Jennifer R. Merritt
Publikováno v:
Experimental Gerontology. 87:57-66
β-Hydroxy β-methylbutyrate (HMB) is a metabolite of the essential amino acid leucine. Recent studies demonstrate a decline in plasma HMB concentrations in humans across the lifespan, and HMB supplementation may be able to preserve muscle mass and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd04e7f539041ed81f41e3b37b54c545
https://doi.org/10.1016/j.exger.2016.11.010
https://doi.org/10.1016/j.exger.2016.11.010
Autor:
Svyatoslav Dvoretskiy, Michael Munroe, Jiayu Leong, Amber Lopez, Christopher M. Adams, Marni D. Boppart, Michael C. Dyle, Hyunjoon Kong
Conditions of extended bed rest and limb immobilization can initiate rapid and significant loss of skeletal muscle mass and function. Physical rehabilitation is standard practice following a period of disuse, yet mobility may be severely compromised,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2287f40faab31941f6186379dd98d18
https://europepmc.org/articles/PMC6529341/
https://europepmc.org/articles/PMC6529341/
Autor:
Tor W. Jensen, Yair Pincu, Ziad S. Mahmassani, Michael Munroe, Kai Zou, Heather D. Huntsman, Michael De Lisio, Koyal Garg, Marni D. Boppart
Publikováno v:
Stem Cell Research, Vol 17, Iss 1, Pp 181-190 (2016)
Adipose tissue expansion during periods of excess nutrient intake requires significant turnover of the extracellular matrix (ECM) to allow for maximal lipid filling. Recent data suggest that stromal cells may be a primary contributor to ECM modificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ec8156682ba5ee8a0329fcc9a02318
http://www.sciencedirect.com/science/article/pii/S1873506116300745
http://www.sciencedirect.com/science/article/pii/S1873506116300745
Autor:
Benjamin F. Miller, Justin J. Reid, Justin S. Rhodes, Marni D. Boppart, Svyatoslav Dvoretskiy, Michael Munroe, Ziad S. Mahmassani, Karyn L. Hamilton
Publikováno v:
Nutritional neuroscience. 23(3)
β-hydroxy β-methylbutyrate (HMB) is a nutritional supplement purported to enhance skeletal muscle mass and strength, as well as cognitive function in older adults. The purpose of this study was to determine the potential for long-term HMB supplemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd41ae85bfdabd2aa5d692246977e92
https://pubmed.ncbi.nlm.nih.gov/29914347
https://pubmed.ncbi.nlm.nih.gov/29914347