Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michael Mulheran"'
Publikováno v:
The Journal of Laryngology & Otology. 129:1174-1181
Objective:To examine whether distortion product otoacoustic emissions can serve as a replacement for pure tone audiometry in longitudinal screening for occupational noise exposure related auditory deficit.Methods:A retrospective review was conducted
Publikováno v:
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-LaryngologyCervico-Facial Surgery. 43(2)
Objectives The surveillance of noise-induced hearing loss (NIHL) according to the Health & Safety Executive (HSE) differs from the medico-legal criteria used to assess NIHL. Our study compares the two systems and proposes a novel method of simplifyin
Autor:
Alan J. Knox, David Stableforth, Pauline Hyman-Taylor, Kelvin H.-V. Tan, Sarah Lewis, Alan R. Smyth, Michael Mulheran
Publikováno v:
Antimicrobial Agents and Chemotherapy. 50:2293-2299
We undertook assessment of hearing in patients with cystic fibrosis who were taking part in a large randomized controlled trial of once- versus three-times-daily tobramycin for pulmonary exacerbations of cystic fibrosis (the TOPIC study). All patient
Autor:
Michael Mulheran, Pauline Hyman-Taylor, Alan J. Knox, Kelvin H.-V. Tan, Sarah Lewis, Alan R. Smyth, David Stableforth
Publikováno v:
The Lancet. 365:573-578
Summary Background Intravenous tobramycin (three-times daily) is widely used for pulmonary exacerbations in patients with cystic fibrosis who have chronic Pseudomonas aeruginosa infection. We undertook a double-blind, randomised controlled trial to a
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 167:819-823
lean mass, of which 70% is body water and the remainder muscle. After intravenous administration, aminoglycosides distribute rapThe potential of aminoglycoside antibiotics to cause ototoxic idly throughout the extracellular fluid compartment, with pe
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:2502-2509
Cystic fibrosis (CF) patients receive repeated courses of aminoglycoside therapy. These patients would consequently be expected to be more susceptible to cochleotoxicity, a recognized side effect with single courses of aminoglycoside therapy. The pri
Publikováno v:
Clinical Otolaryngology and Allied Sciences. 25:570-576
INTRODUCTION: Pharmacological protection of cochlear function is one of the most exciting goals of inner ear medicine. The selective glutamate antagonist MK 801 may be neuro-protective to the cochlea.1 This study aims to investigate whether round win
Autor:
S. Etheridge, Michael Mulheran
Publikováno v:
Clinical Otolaryngology and Allied Sciences. 24:82-89
Autor:
Ernest S. Harpur, Michael Mulheran
Publikováno v:
British Journal of Audiology. 32:47-56
Single doses of gentamicin and furosemide given in combination result in a rapid and profound loss of cochlear function. In this study, measurement of three gross cochlear potentials (cochlear microphonics, compound action potentials and the endococh
Autor:
George Kosmadakis, Alan Bevington, Emma L. Watson, Karen Molyneux, João L. Viana, Izabella Z.A. Pawluczyk, Alice C. Smith, John Feehally, Michael Mulheran, Susan M. Shirreffs, Ronald J. Maughan, J. Brown, Christopher W. McIntyre, Nicolette C. Bishop, Stephen G. John, Paul J. Owen
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Muscle-wasting in chronic kidney disease (CKD) arises from several factors including sedentary behaviour and metabolic acidosis. Exercise is potentially beneficial but might worsen acidosis through exercise-induced lactic acidosis. We studied the chr