Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Michael Morabito"'
Autor:
Sungtek Park, Zhaoyuan Wang, Frederick Stern, Nicholas Husser, Stefano Brizzolara, Michael Morabito, Evan Lee
Publikováno v:
Ocean Engineering. 261:112047
Publikováno v:
Biophys J
We perform single-molecule flow experiments using confocal microscopy and a microfluidic device for shear rates up to 20,000 s−1 and present results for the shear-induced unraveling and elongation of tethered von Willebrand factor (VWF) multimers.
Publikováno v:
Canadian Journal of Physics. 96:1272-1287
Hollow fiber membrane (HFM) modules are among the most common separation devices employed in membrane separation applications. Three-dimensional steady-state computational fluid dynamics (CFD) simulations are carried out to study flow past hollow fib
Autor:
Alparslan Oztekin, Michael Morabito, Alaa Hakim, Ali E. Anqi, Mustafa Usta, Mohammed Alrehili
Publikováno v:
Desalination. 441:21-34
We show how a simple design adaptation creates desirable flow structures that dramatically enhance performance in hollow fiber membrane (HFM) water desalination modules using computational fluid dynamics (CFD) simulations. Conventional HFM desalinati
Autor:
Chuqiao Dong, Xuanhong Cheng, Michael Morabito, Sagar Kania, Alparslan Oztekin, Wonpil Im, Edmund B. Webb, X. Frank Zhang
Publikováno v:
The Journal of chemical physics. 151(12)
The von Willebrand Factor (vWF) is a large blood glycoprotein that aids in hemostasis. Within each vWF monomer, the A2 domain hosts a cleavage site for enzyme ADAMTS13, which regulates the size of vWF multimers. This cleavage site can only be exposed
Autor:
Xuanhong Cheng, Edmund B. Webb, Michael Morabito, Alparslan Oztekin, Xiaohui F. Zhang, Mustafa Usta
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
We develop a machine learning tool useful for predicting the instantaneous dynamical state of sub-monomer features within long linear polymer chains, as well as extracting the dominant macromolecular motions associated with sub-monomer behaviors of i
Autor:
Alparslan Oztekin, Chuqiao Dong, Xuanhong Cheng, Michael Morabito, Wei Wei, Edmund B. Webb, X. Frank Zhang
Using Brownian molecular dynamics simulations, we examine the internal dynamics and biomechanical response of von Willebrand Factor (vWF) multimers subject to shear flow. The coarse grain multimer description employed here is based on a monomer model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eaaf2235888d956b7d95ff370addacf
https://doi.org/10.1101/312405
https://doi.org/10.1101/312405
Autor:
Alaa Hakim, Ali E. Anqi, Alparslan Oztekin, Mustafa Usta, Mohammed Alrehili, Michael Morabito
Publikováno v:
Volume 7: Fluids Engineering.
Reverse Osmosis (RO) is a process whereby solutes are removed from a solution by means of a semipermeable membrane. Providing access to clean water is one of our generation’s grand engineering challenges, and RO processes are taking center stage in
Autor:
Xuanhong Cheng, X. Frank Zhang, Michael Morabito, Wei Wei, Edmund B. Webb, Alparslan Oztekin, Chuqiao Dong
Publikováno v:
Biophysical journal. 114(8)
Von Willebrand factor (VWF) is a large multimeric protein that aids in blood clotting. Near injury sites, hydrodynamic force from increased blood flow elongates VWF, exposing binding sites for platelets and collagen. To investigate VWF binding to col
Autor:
Yi Wang, Chuqiao Dong, Sagar Kania, Edmund B. Webb, Alp Oztekin, Xiaohui Zhang, Xuanhong Cheng, Michael Morabito
Publikováno v:
Biophysical Journal. 116:323a