Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Michael Möllmann"'
Autor:
Meike Farber, Yiyang Chen, Lucas Arnold, Michael Möllmann, Eva Boog-Whiteside, Yu-An Lin, H. Christian Reinhardt, Ulrich Dührsen, Maher Hanoun
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Targeting the interaction between leukemic cells and the microenvironment is an appealing approach to enhance the therapeutic efficacy in acute myeloid leukemia (AML). AML infiltration induces a significant release of inflammatory cytokines
Externí odkaz:
https://doaj.org/article/d97d5af41fbb4c26838feff8bdc564fe
Autor:
Patricia Johansson, Laura Dierichs, Ludger Klein-Hitpass, Anke K. Bergmann, Michael Möllmann, Sascha Menninger, Peter Habenberger, Bert Klebl, Jens T. Siveke, Ulrich Dührsen, Axel Choidas, Jan Dürig
Publikováno v:
Therapeutic Advances in Hematology, Vol 11 (2020)
T-cell prolymphocytic leukemia (T-PLL) is an aggressive malignancy characterized by chemotherapy resistance and a median survival of less than 2 years. Here, we investigated the pharmacological effects of the novel highly specific cyclin-dependent ki
Externí odkaz:
https://doaj.org/article/dbaad95c53fa476da2bd0fedf8b2e735
Autor:
Maria Dampmann, André Görgens, Michael Möllmann, Florian Murke, Ulrich Dührsen, Bernd Giebel, Jan Dürig
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228674 (2020)
In order to accomplish their physiological functions leukocytes have the capability to migrate. As a prerequisite they need to adopt a polarized cell shape, forming a leading edge at the front and a uropod at rear pole. In this study we explored the
Externí odkaz:
https://doaj.org/article/04600eac45574d06a3496f2a97da996d
Autor:
Maurizio Mangolini, Frederik Götte, Andrew Moore, Tim Ammon, Madlen Oelsner, Gloria Lutzny-Geier, Ludger Klein-Hitpass, James C. Williamson, Paul J. Lehner, Jan Dürig, Michael Möllmann, Lívia Rásó-Barnett, Katherine Hughes, Antonella Santoro, Simón Méndez-Ferrer, Robert A. J. Oostendorp, Ursula Zimber-Strobl, Christian Peschel, Daniel J. Hodson, Marc Schmidt-Supprian, Ingo Ringshausen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The Wnt pathway is one of the core de-regulated pathways in chronic lymphocytic leukaemia (CLL) and is activated in only a subset of patients; however, no universal drivers of the disease have been identified. Here the authors show that Notch2 and β
Externí odkaz:
https://doaj.org/article/c4f9c099f3104cabbf026773512a17d1
Autor:
André Görgens, Anna-Kristin Ludwig, Michael Möllmann, Adalbert Krawczyk, Jan Dürig, Helmut Hanenberg, Peter A. Horn, Bernd Giebel
Publikováno v:
Stem Cell Reports, Vol 3, Iss 6, Pp 1058-1072 (2014)
Hematopoietic stem and progenitor cells (HSPCs) can self-renew and create committed progenitors, a process supposed to involve asymmetric cell divisions (ACDs). Previously, we had linked the kinetics of CD133 expression with ACDs but failed to detect
Externí odkaz:
https://doaj.org/article/7bf0fac9c1184c6aa08394f3ed9b951a
Publikováno v:
Anesthesiology Research and Practice, Vol 2017 (2017)
Background. Effects of perioperative cervical level neuraxial blocks on the dissemination of cancer metastases have become a matter of substantial interest. However, experience with these catheters has been limited and data on feasibility and efficac
Externí odkaz:
https://doaj.org/article/a17006f6d89d4d9c8008ae8ec07bd4f6
Autor:
André Görgens, Stefan Radtke, Michael Möllmann, Michael Cross, Jan Dürig, Peter A. Horn, Bernd Giebel
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1539-1552 (2013)
The classical model of hematopoiesis predicts a dichotomous lineage restriction of multipotent hematopoietic progenitors (MPPs) into common lymphoid progenitors (CLPs) and common myeloid progenitors (CMPs). However, this idea has been challenged by t
Externí odkaz:
https://doaj.org/article/fb90a55064f94a56ace1749809d96e29
Autor:
André Görgens, Anna-Kristin Ludwig, Michael Möllmann, Adalbert Krawczyk, Jan Dürig, Helmut Hanenberg, Peter A. Horn, Bernd Giebel
Publikováno v:
Stem Cell Reports, Vol 5, Iss 1, Pp 154-155 (2015)
Externí odkaz:
https://doaj.org/article/16e0cb0bd9554b258fe0b38b00d7b42f
Autor:
Maria Göbel, Lewin Eisele, Michael Möllmann, Andreas Hüttmann, Patricia Johansson, René Scholtysik, Manuela Bergmann, Raymonde Busch, Hartmut Döhner, Michael Hallek, Till Seiler, Stephan Stilgenbauer, Ludger Klein-Hitpass, Ulrich Dührsen, Jan Dürig
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72107 (2013)
Progranulin (Pgrn) is a 88 kDa secreted protein with pleiotropic functions including regulation of cell cycle progression, cell motility, wound repair and tumorigenesis. Using microarray based gene expression profiling we have recently demonstrated t
Externí odkaz:
https://doaj.org/article/9703eff2c92f44caa45af17aed231c40
Publikováno v:
Anesthesiology Research and Practice, Vol 2012 (2012)
Background. Complications of spinal anaesthesia (SpA) range between 1 and 17%. Habitus and operator experience may play a pivotal role, but only sparse data is available to substantiate this claim. Methods. 161 patients were prospectively enrolled. D
Externí odkaz:
https://doaj.org/article/2c44ae52be9140e8b079e7796c98bd78