Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Michael Milyavsky"'
Autor:
Eitan Kugler, Shreyas Madiwale, Darren Yong, Julie A. I. Thoms, Yehudit Birger, David B. Sykes, Johannes Schmoellerl, Aneta Drakul, Valdemar Priebe, Muhammad Yassin, Nasma Aqaqe, Avigail Rein, Hila Fishman, Ifat Geron, Chun-Wei Chen, Brian Raught, Qiao Liu, Heather Ogana, Elisabeth Liedke, Jean-Pierre Bourquin, Johannes Zuber, Michael Milyavsky, John Pimanda, Gilbert G. Privé, Shai Izraeli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The ERG (ETS-related gene) transcription factor is linked to various types of cancer, including leukemia. However, the specific ERG domains and co-factors contributing to leukemogenesis are poorly understood. Drug targeting a transcription f
Externí odkaz:
https://doaj.org/article/d7035b0bdc8b4304be06aaa591c4d83a
Autor:
Tzah Feldman, Akhiad Bercovich, Yoni Moskovitz, Noa Chapal-Ilani, Amanda Mitchell, Jessie J. F. Medeiros, Tamir Biezuner, Nathali Kaushansky, Mark D. Minden, Vikas Gupta, Michael Milyavsky, Zvi Livneh, Amos Tanay, Liran I. Shlush
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The mutational mechanisms that produce insertions and deletions that lead to clonal hematopoiesis are poorly understood. Here the authors show evidence that frequent deletions that are relevant to myeloid malignancies could be produced by PARP1-depen
Externí odkaz:
https://doaj.org/article/5cd49203803b4c6e921be0f40f64c457
Autor:
Shahar Biechonski, Leonid Olender, Adi Zipin-Roitman, Muhammad Yassin, Nasma Aqaqe, Victoria Marcu-Malina, Melanie Rall-Scharpf, Magan Trottier, M. Stephen Meyn, Lisa Wiesmüller, Katia Beider, Yael Raz, Dan Grisaru, Arnon Nagler, Michael Milyavsky
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Failure to precisely repair DNA damage in self-renewing Hematopoietic Stem and early Progenitor Cells (HSPCs) can disrupt normal hematopoiesis and promote leukemogenesis. Although HSPCs are widely considered a target of ionizing radiation (I
Externí odkaz:
https://doaj.org/article/9313fac1c8ce4adb8917c5a6468462c9
Autor:
Yosef Buganim, Ido Goldstein, Doron Lipson, Michael Milyavsky, Sylvie Polak-Charcon, Corine Mardoukh, Hilla Solomon, Eyal Kalo, Shalom Madar, Ran Brosh, Marina Perelman, Roy Navon, Naomi Goldfinger, Iris Barshack, Zohar Yakhini, Varda Rotter
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9657 (2010)
Partial gain of chromosome arm 17q is an abundant aberrancy in various cancer types such as lung and prostate cancer with a prominent occurrence and prognostic significance in neuroblastoma--one of the most common embryonic tumors. The specific genet
Externí odkaz:
https://doaj.org/article/a72d18ed0d5d466abdd0817d1a86e473
Autor:
Diana Rasoulouniriana, Nadine Santana-Magal, Amit Gutwillig, Leen Farhat-Younis, Lior Tal, Sarah Amar, Michael Milyavsky, Siva Sai Naga Anurag Muddineni, Neta Solomon, Hana Shpilt, Shahar Dotan, Noam Pilpel, Claudia Waskow, Meora Feinmesser, Peleg Rider, Yaron Carmi
Publikováno v:
Cancer Immunology Research. :OF1-OF18
The pioneering design of chimeric antigen receptor (CAR) T-cell therapy demonstrated the potential of reprogramming the immune system. Nonetheless, T-cell exhaustion, toxicity, and suppressive microenvironments limit their efficacy in solid tumors. W
Autor:
Yaron Carmi, Peleg Rider, Meora Feinmesser, Claudia Waskow, Noam Pilpel, Shahar Dotan, Hana Shpilt, Neta Solomon, Siva Sai Naga Anurag Muddineni, Michael Milyavsky, Sarah Amar, Lior Tal, Leen Farhat-Younis, Amit Gutwillig, Nadine Santana-Magal, Diana Rasoulouniriana
Supplementary tables and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a828b462c9d6002c2d495c8387f825dc
https://doi.org/10.1158/2326-6066.22651051
https://doi.org/10.1158/2326-6066.22651051
Autor:
Michael Milyavsky, Shai Izraeli, John E. Dick, Amanda Mitchell, Olga I. Gan, Eric R. Lechman, Eitan Kugler, Adi Zipin-Roitman, Chen Katz-Even, Nour Ershaid, Abed Alkader Yassin, Muhammad Yassin, Nasma Aqaqe
Supplementary Table 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d38cdd05897a9bc033df1cc75fdc4c0
https://doi.org/10.1158/0008-5472.22422524.v1
https://doi.org/10.1158/0008-5472.22422524.v1
Autor:
Michael Milyavsky, Shai Izraeli, John E. Dick, Amanda Mitchell, Olga I. Gan, Eric R. Lechman, Eitan Kugler, Adi Zipin-Roitman, Chen Katz-Even, Nour Ershaid, Abed Alkader Yassin, Muhammad Yassin, Nasma Aqaqe
Supplementary Table 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5bdfefcc69c463f17fb05156aae33d
https://doi.org/10.1158/0008-5472.22422527.v1
https://doi.org/10.1158/0008-5472.22422527.v1
Autor:
Michael Milyavsky, Shai Izraeli, John E. Dick, Amanda Mitchell, Olga I. Gan, Eric R. Lechman, Eitan Kugler, Adi Zipin-Roitman, Chen Katz-Even, Nour Ershaid, Abed Alkader Yassin, Muhammad Yassin, Nasma Aqaqe
Acute leukemia is a rapidly progressing blood cancer with low survival rates. Unfavorable prognosis is attributed to insufficiently characterized subpopulations of leukemia stem cells (LSC) that drive chemoresistance and leukemia relapse. Here we uti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbd22ac8cd34a1c15868cb537e285ada
https://doi.org/10.1158/0008-5472.c.6511256.v1
https://doi.org/10.1158/0008-5472.c.6511256.v1
Autor:
Michael Milyavsky, Shai Izraeli, John E. Dick, Amanda Mitchell, Olga I. Gan, Eric R. Lechman, Eitan Kugler, Adi Zipin-Roitman, Chen Katz-Even, Nour Ershaid, Abed Alkader Yassin, Muhammad Yassin, Nasma Aqaqe
Supplementary figure legends and full list of materials and methods references
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270e9aada8c7fe4abba16775b9befbf3
https://doi.org/10.1158/0008-5472.22422536
https://doi.org/10.1158/0008-5472.22422536