Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Michael Mihlan"'
Autor:
Felix Jünger, Dominic Ruh, Dominik Strobel, Rebecca Michiels, Dominik Huber, Annette Brandel, Josef Madl, Alina Gavrilov, Michael Mihlan, Caterina Cora Daller, Eva A. Rog-Zielinska, Winfried Römer, Tim Lämmermann, Alexander Rohrbach
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
In live-cell microscopy, motion blur limits resolution and contrast. Here the authors use 100 Hz super-resolving Rotating Coherent Scattering (ROCS) microscopy on various dynamic biological systems, and time-window analysis to understand biological e
Externí odkaz:
https://doaj.org/article/509e82a9756a4bb79547e54b6d5943ca
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Neutrophils are key cells of our innate immune response with essential roles for eliminating bacteria and fungi from tissues. They are also the prototype of an amoeboid migrating leukocyte. As one of the first blood-recruited immune cell types during
Externí odkaz:
https://doaj.org/article/4fc8414694e141aca0b7327547dc8bb3
Autor:
Silvia Slesiona, Markus Gressler, Michael Mihlan, Christoph Zaehle, Martin Schaller, Dagmar Barz, Bernhard Hube, Ilse D Jacobsen, Matthias Brock
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31223 (2012)
Invasive bronchopulmonary aspergillosis (IBPA) is a life-threatening disease in immunocompromised patients. Although Aspergillus terreus is frequently found in the environment, A. fumigatus is by far the main cause of IBPA. However, once A. terreus e
Externí odkaz:
https://doaj.org/article/3ce818b2566540f8b3f70a4df7de6974
Autor:
Lukas Kaltenbach, Paloma Martzloff, Sarah K. Bambach, Nadim Aizarani, Michael Mihlan, Alina Gavrilov, Katharina M. Glaser, Manuel Stecher, Roland Thünauer, Aude Thiriot, Klaus Heger, Katrin Kierdorf, Stephan Wienert, Ulrich H. von Andrian, Marc Schmidt-Supprian, Claus Nerlov, Frederick Klauschen, Axel Roers, Marc Bajénoff, Dominic Grün, Tim Lämmermann
Publikováno v:
Nature Immunology
Nature Immunology, 2023, 24, pp.915-924. ⟨10.1038/s41590-023-01493-2⟩
Nature Immunology, 2023, 24, pp.915-924. ⟨10.1038/s41590-023-01493-2⟩
Immune cell locomotion is associated with amoeboid migration, a flexible mode of movement, which depends on rapid cycles of actin polymerization and actomyosin contraction1. Many immune cells do not necessarily require integrins, the major family of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d1b64309963a8263cb0f2d5a0ac0fe
https://amu.hal.science/hal-04155979/document
https://amu.hal.science/hal-04155979/document
Autor:
Sarah K. Bambach, Lukas Kaltenbach, Nadim Aizarani, Paloma Martzloff, Alina Gavrilov, Katharina M. Glaser, Roland Thünauer, Michael Mihlan, Manuel Stecher, Aude Thiriot, Stephan Wienert, Ulrich von Andrian, Marc Schmidt-Supprian, Claus Nerlov, Frederick Klauschen, Axel Roers, Marc Bajénoff, Dominic Grün, Tim Lämmermann
SUMMARYMany leukocytes use fast and flexible amoeboid migration strategies to move autonomously throughout tissues. Here, we show that the movement of mast cells (MCs), leukocytes with important roles during allergies and anaphylaxis, fundamentally d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e92b44eb7e9245a48675ea63bc8d4f0d
https://doi.org/10.1101/2022.07.19.500614
https://doi.org/10.1101/2022.07.19.500614
Publikováno v:
Annual Review of Cell and Developmental Biology
Successful immune responses depend on the spatiotemporal coordination of immune cell migration, interactions, and effector functions in lymphoid and parenchymal tissues. Real-time intravital microscopy has revolutionized our understanding of the dyna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d051209ee8c3edf3d5b38d6b26f83f9
https://hdl.handle.net/21.11116/0000-000B-0716-521.11116/0000-000B-0718-3
https://hdl.handle.net/21.11116/0000-000B-0716-521.11116/0000-000B-0718-3
Autor:
Ev-Marie Schuster, Maximilian W. Epple, Katharina M. Glaser, Michael Mihlan, Kerstin Lucht, Julia A. Zimmermann, Anna Bremser, Aikaterini Polyzou, Nadine Obier, Nina Cabezas-Wallscheid, Eirini Trompouki, Andrea Ballabio, Jörg Vogel, Joerg M. Buescher, Alexander J. Westermann, Angelika S. Rambold
Publikováno v:
Nature Metabolism
Successful elimination of bacteria in phagocytes occurs in the phago-lysosomal system, but also depends on mitochondrial pathways. Yet, how these two organelle systems communicate is largely unknown. Here we identify the lysosomal biogenesis factor t
Autor:
Felix Jünger, Dominic Ruh, Dominik Strobel, Rebecca Michiels, Dominik Huber, Annette Brandel, Josef Madl, Alina Gavrilov, Michael Mihlan, Caterina Cora Daller, Eva A. Rog-Zielinska, Winfried Römer, Tim Lämmermann, Alexander Rohrbach
Publikováno v:
Nature Communications
Fluorescence techniques dominate the field of live-cell microscopy, but bleaching and motion blur from too long integration times limit dynamic investigations of small objects. High contrast, label-free life-cell imaging of thousands of acquisitions
Autor:
Teresa K. Tarrant, Sarah Eickhoff, Konrad Knöpper, Eduardo Reátegui, Maximilian W. Epple, Katharina M. Glaser, Ralf Baumeister, Matthias Gunzer, Wolfgang Kastenmüller, Ronald N. Germain, Daniel Irimia, Michael Mihlan, Tim Lämmermann, Korbinian Kienle
Publikováno v:
Science
Stopping the swarmNeutrophils play a major role in the early immune response and are recruited in large numbers into inflamed and infected tissues. By secreting chemoattractants that bind G protein–coupled receptors (GPCRs) on neighboring cells, ne
Publikováno v:
Current Opinion in Cell Biology
Several immune cell types (neutrophils, eosinophils, T cells, and innate-like lymphocytes) display coordinated migration patterns when a population, formed of individually responding cells, moves through inflamed or infected tissues. “Swarming” r