Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Michael Merger"'
Autor:
Christine Duffy, Melissa Lynne Johnson, Ben George, Susanna Varkey Ulahannan, Miaomiao Ge, Ralph Graeser, Renee Landsberg, Quincy Chu, Mabrouk Elgadi, Manish Patel, Johanna C. Bendell, Wenbo Tang, Michael Merger
Publikováno v:
Molecular Cancer Therapeutics. 18:C027-C027
Background: Inhibition of the PD-1 pathway is an effective immunotherapeutic approach in a subset of patients with various solid tumors and hematologic malignancies. Blockade of the PD-1 pathway leads to overexpression of other checkpoint receptors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30ce6ce0091c8047e8ddefb422f5944b
https://doi.org/10.1158/1535-7163.targ-19-c027
https://doi.org/10.1158/1535-7163.targ-19-c027
Autor:
Jean-Pierre Droz, Rolf Kaiser, Michael Merger, Christine Chevreau, Helene De Mont-Serrat, Jaques Medioni, Stéphane Oudard, Peter Stopfer
Publikováno v:
Anti-Cancer Drugs. 25:1081-1088
This open-label, phase II trial assessed the efficacy and safety of two doses of nintedanib, a triple angiokinase inhibitor targeting vascular endothelial growth factor, fibroblast growth factor, and platelet-derived growth factor signaling, in patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04473919ae746938563989b23c580c3b
https://doi.org/10.1097/cad.0000000000000131
https://doi.org/10.1097/cad.0000000000000131
Autor:
Michael Merger, Gordon J. S. Rustin, Timothy J. Perren, Jonathan A. Ledermann, Helena M. Earl, Allan Hackshaw, Iain A. McNeish, Stan B. Kaye, Graham Temple, Malcolm Adams, Martin Gore, Hani Gabra, LE James, M. Persic, Gordon C Jayson
Publikováno v:
Journal of Clinical Oncology. 29:3798-3804
Purpose Inhibiting angiogenesis is one of the most promising avenues for new therapies for ovarian cancer. We investigated the efficacy and safety of a novel agent, BIBF 1120, a triple angiokinase inhibitor, after chemotherapy for relapsed disease. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d1abe4df039182cceaa0aadc1b0f2e
https://doi.org/10.1200/jco.2010.33.5208
https://doi.org/10.1200/jco.2010.33.5208
Autor:
Rajka Borojevic, Pengfei Zhou, Robert H. Riddell, R Maric, Michael Merger, Kenneth Croitoru, David A. Clark, Eckhard R. Podack, Darlene Steele-Norwood, Joanne L. Viney
Publikováno v:
Gut. 51:155-163
Background and aims: Mucosal flattening and epithelial cell apoptosis are typical features of T cell induced inflammatory diseases of the bowel, such as coeliac disease and graft versus host disease. Mice injected with a T cell activating anti-CD3 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2534007f3612ab8eff2e000378e5d8fd
https://doi.org/10.1136/gut.51.2.155
https://doi.org/10.1136/gut.51.2.155
Autor:
Johanna Hell, Alexander Reuss, Petronella B. Ottevanger, Andreas du Bois, Florian Heitz, Jørn Herrstedt, Jalid Sehouli, Andres Poveda, Elisabeth Åvall-Lundqvist, Ignace Vergote, Nicoletta Colombo, Patricia Pautier, Michael Merger, Arto Leminen, Gennaro Cormio, Lars Hanker, Jérôme Alexandre, Bent Fiane, Ulrich Canzler, Philipp Harter
Publikováno v:
Journal of Clinical Oncology. 35:5521-5521
5521 Background: Post-OP TR is a strong prognostic factor in AOC; the best prognosis is observed after complete resection (TR0). TR assessment is performed at the end of the surgery and may be exposed to personal bias. Pre-Chemo CT may improve post-O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4874fbcbc8f0a494152bffbb79cafe5
https://doi.org/10.1200/jco.2017.35.15_suppl.5521
https://doi.org/10.1200/jco.2017.35.15_suppl.5521
Autor:
Jalid Sehouli, F Marmé, Rainer Kimmig, David Cibula, A Reuß, Annette Hasenburg, A. du Bois, Alexander Burges, Michael Merger, Martina Gropp-Meier, Tanja Fehm, W Meier, Lars Hanker, P. Harter, N de Gregorio, Antje Belau, J Kosse, K Baumann, B Schmalfeldt, Felix Hilpert, Barbara Richter, Ulrich Canzler, S Mahner, Jacobus Pfisterer
Publikováno v:
Geburtshilfe und Frauenheilkunde. 74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993e951591165bc9fed0052bb0412aea
https://doi.org/10.1055/s-0034-1388329
https://doi.org/10.1055/s-0034-1388329
Autor:
Lars Hanker, Jacobus Pfisterer, Rainer Kimmig, Marc Thill, Michael Merger, Barbara Richter, Annette Hasenburg, Petra Krabisch, Bernd Gerber, Felix Hilpert, S Mahner, O Sailer, M. Gropp, A. du Bois, Tanja Fehm, N de Gregorio, Antje Belau, Uwe Herwig, B Schmalfeldt, Ulrich Canzler, W Meier, C. Liebrich, K Baumann, P. Harter, Jochem Potenberg, J Kosse, David Cibula, Jalid Sehouli, F Marmé, Alexander Burges
Publikováno v:
Geburtshilfe und Frauenheilkunde. 74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::457b4022e0f6310cefc41b8509460e26
https://doi.org/10.1055/s-0034-1388364
https://doi.org/10.1055/s-0034-1388364
Autor:
Meg Mosteller-Barnum, Marty T. Sellers, Don A. Sibley, Jan M. Orenstein, Michael Merger, Toshihide Shimada, Michael W. Russell, Lesley E. Smythies, Martin F. Graham, Hiromi Kubagawa, Phillip D. Smith
Publikováno v:
The Journal of Immunology. 167:2651-2656
The intestinal mucosa normally displays minimal inflammation despite the close proximity between mucosal macrophages and lumenal bacteria. Macrophages interact with bacteria and their products through CD14, a surface receptor involved in the response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8fa670c08491fc611cae1d95d0491f
https://doi.org/10.4049/jimmunol.167.5.2651
https://doi.org/10.4049/jimmunol.167.5.2651
Autor:
Stephen M. Collins, Derek M. McKay, Michael Merger, Nikola Radojevic, Kenneth Croitoru, Bruce A. Vallance
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 276:R715-R723
Specific in vivo T cell activation initiated by treatment with anti-CD3 antibodies leads to diarrhea and structural damage of the intestinal mucosa. In this study, the effect of T cell-induced mucosal damage on jejunal epithelial ion transport, muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80b1fd9349175eef92cd96b9301fe7d
https://doi.org/10.1152/ajpregu.1999.276.3.r715
https://doi.org/10.1152/ajpregu.1999.276.3.r715
Autor:
Han Hsi Wong, James D. Brenton, Jonathan A. Ledermann, Christine Parkinson, Aileen Patterson, Helena M. Earl, Ashley Shaw, Mahmood I. Shafi, Michael Merger
► Nintedanib is an anti-angiogenic agent that has demonstrated activity in relapsed ovarian cancer. ► Our patient had prolonged response to nintedanib, allowing her to have potentially curative surgery 6 years after her diagnosis. ► The relatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8986133382af10e3d7669242b91041
https://europepmc.org/articles/PMC3862224/
https://europepmc.org/articles/PMC3862224/
