Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Michael McCauley"'
Autor:
Kaija L. Zusevics, Kimberly Strong, Michael McCauley, Alison La Pean Kirschner, Jessica Jeruzal, Samantha Wilson, Carmen Knight, Thomas May
Publikováno v:
Journal of Community Engagement and Scholarship, Vol 10, Iss 2 (2022)
We identify concerns pertinent to establishing trust necessary to support adoptees’ confidence in and uptake of genetic testing that might allow them to benefit from early screening and medical intervention. Using principles of community-based part
Externí odkaz:
https://doaj.org/article/39d1480819e24e4f9da53997ce7afee4
Autor:
Gino Cingolani, Michael McCauley, Anna Lobley, Alexander J. Bryer, Jordan Wesolowski, Deanna L. Greco, Ravi K. Lokareddy, Erik Ronzone, Juan R. Perilla, Fabienne Paumet
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Chlamydia trachomatis forms membrane-bound inclusions inside the host cell that are decorated with IncA, a SNARE-like protein that promotes the fusion of inclusions. Here, Cingolani et al. show that the protein folds into a non-canonical four-helix b
Externí odkaz:
https://doaj.org/article/d9b4e46bb6f643ab90bbf0b252996fa0
Autor:
Shalom D. Goldberg, Nathan Felix, Michael McCauley, Ryan Eberwine, Lou Casta, Kathleen Haskell, Tricia Lin, Elizabeth Palovick, Donna Klein, Lori Getts, Robert Getts, Mimi Zhou, Pratima Bansal-Pakala, Vadim Dudkin
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1669 (2021)
Autoimmune diseases such as rheumatoid arthritis are caused by immune system recognition of self-proteins and subsequent production of effector T cells that recognize and attack healthy tissue. Therapies for these diseases typically utilize broad imm
Externí odkaz:
https://doaj.org/article/2e31a379f8b44670a74707a7406eed86
Autor:
Marie-France Langelier, Michael McCauley, Elizabeth Underwood, Laura E. Easton, Ji-Chun Yang, David Neuhaus, Kevin J. Embrey, Philip B. Rawlins, John M. Pascal, Marianne Schimpl, Tom E. H. Ogden
Publikováno v:
Nucleic Acids Research
PARP-1 is a key early responder to DNA damage in eukaryotic cells. An allosteric mechanism links initial sensing of DNA single-strand breaks by PARP-1’s F1 and F2 domains via a process of further domain assembly to activation of the catalytic domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797bf973be4d902f491aa1173a7f7e07
https://doi.org/10.1093/nar/gkab020
https://doi.org/10.1093/nar/gkab020
Publikováno v:
Eur J Heart Fail
Aims To assess whether natriuretic peptides (NPs) can be used to reliably predict long-term therapeutic effect on clinical outcomes for patients with heart failure and reduced ejection fraction (HFrEF). Methods and results HFrEF intervention trials w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b6da8d4ab652ebd140207677c77d63
https://doi.org/10.1002/ejhf.1411
https://doi.org/10.1002/ejhf.1411
Publikováno v:
Rhode Island medical journal (2013). 103(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d407667a09071ec93ec3eb0d194a16e
https://pubmed.ncbi.nlm.nih.gov/33261233
https://pubmed.ncbi.nlm.nih.gov/33261233
Autor:
Michael McCauley, Swati Roy, Marie-France Langelier, Kushol Gupta, Travis Eisemann, Gregory D. Van Duyne, John M. Pascal
Publikováno v:
Structure. 24:1679-1692
The poly(ADP-ribose) polymerase enzyme Tankyrase-1 (TNKS) regulates multiple cellular processes and interacts with diverse proteins using five ankyrin repeat clusters (ARCs). There are limited structural insights into functional roles of the multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52cd469685c4d16ee1fa6c9941257875
https://doi.org/10.1016/j.str.2016.07.014
https://doi.org/10.1016/j.str.2016.07.014
Publikováno v:
Structure. 24:1573-1581
Tankyrase-1 (TNKS1/PARP-5a) is a poly(ADP-ribose) polymerase (PARP) enzyme that regulates multiple cellular processes creating a poly(ADP-ribose) posttranslational modification that can lead to target protein turnover. TNKS1 thereby controls protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fcb90b7fd80845735047c189825d3b5
https://doi.org/10.1016/j.str.2016.06.022
https://doi.org/10.1016/j.str.2016.06.022
Autor:
Michael McCauley, Johnell McCauley
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Autor:
Hossein Sarrafzadeh, Hanif Mohaddes Deylami, Tamsin Kingston, Michael McCauley, Iman Tabatabaei Ardekani, Mahsa Mohaghegh
Publikováno v:
International Journal in Foundations of Computer Science & Technology. 5:55-66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fe10eae11a3f4247345927e4e252f7c
https://doi.org/10.5121/ijfcst.2015.5606
https://doi.org/10.5121/ijfcst.2015.5606