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of 3
pro vyhledávání: '"Michael McCane"'
Autor:
Greg J. Duncan, Sam D. Ingram, Katie Emberley, Jo Hill, Christian Cordano, Ahmed Abdelhak, Michael McCane, Jennifer E. Jenks, Nora Jabassini, Kirtana Ananth, Skylar J. Ferrara, Brittany Stedelin, Benjamin Sivyer, Sue A. Aicher, Thomas S. Scanlan, Trent A. Watkins, Anusha Mishra, Jonathan W. Nelson, Ari J. Green, Ben Emery
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Chronic demyelination and oligodendrocyte loss deprive neurons of crucial support. It is the degeneration of neurons and their connections that drives progressive disability in demyelinating disease. However, whether chronic demyelination tr
Externí odkaz:
https://doaj.org/article/157dbf6e704c453ab56f2275e3086749
Publikováno v:
Cancer Research. 83:3247-3247
Background: The role of endoplasmic reticulum (ER) stress is profound in increasing malignant activity of neoplastic tumor cells and has been recently demonstrated to also increase immunosuppressive activity of tumor-associated macrophages (TAMs). Im
Autor:
Younjung Park, Hyeyoung Cho, Seung-Hee Lee, Wenxian Wang, Michael McCane, Yungki Park, Sangsoo Kim, Sue A. Aicher, Dongkyeong Kim, Ben Emery, Jae Woon Lee, Soo Kyung Lee, Sung Min Yoon, Ji Hwan Moon, Su Jeong Lim
Publikováno v:
Cell reports
SUMMARY PRC2 creates the repressive mark histone H3 Lys27 trimethylation. Although PRC2 is involved in various biological processes, its role in glial development remains ambiguous. Here, we show that PRC2 is required for oligodendrocyte (OL) differe