Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Michael Margaliot"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The rate of mRNA translation depends on the initiation, elongation, and termination rates of ribosomes along the mRNA. These rates depend on many “local” factors like the abundance of free ribosomes and tRNA molecules in the vicinity of
Externí odkaz:
https://doaj.org/article/444da30749464f0a930644f1049d60c7
Publikováno v:
Royal Society Open Science, Vol 8, Iss 9 (2021)
A dynamical system entrains to a periodic input if its state converges globally to an attractor with the same period. In particular, for a constant input, the state converges to a unique equilibrium point for any initial condition. We consider the pr
Externí odkaz:
https://doaj.org/article/5d60053f07a34ffc88b486b10fbfa1a6
Publikováno v:
Royal Society Open Science, Vol 5, Iss 4 (2018)
The master equation plays an important role in many scientific fields including physics, chemistry, systems biology, physical finance and sociodynamics. We consider the master equation with periodic transition rates. This may represent an external pe
Externí odkaz:
https://doaj.org/article/688656861ce6409fbe68e4ec04995f75
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182178 (2017)
In many important cellular processes, including mRNA translation, gene transcription, phosphotransfer, and intracellular transport, biological "particles" move along some kind of "tracks". The motion of these particles can be modeled as a one-dimensi
Externí odkaz:
https://doaj.org/article/e212f5b08bab47808f70654432612637
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177650 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0166481.].
Externí odkaz:
https://doaj.org/article/fafb7c4cefaf428ca89f85296db86f73
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182074 (2017)
Natural phenomena frequently involve a very large number of interacting molecules moving in confined regions of space. Cellular transport by motor proteins is an example of such collective behavior. We derive a deterministic compartmental model for t
Externí odkaz:
https://doaj.org/article/2f9237287e354308ae4207f296cc49ba
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166481 (2016)
During mRNA translation, several ribosomes attach to the same mRNA molecule simultaneously translating it into a protein. This pipelining increases the protein translation rate. A natural and important question is what ribosomal density maximizes the
Externí odkaz:
https://doaj.org/article/d0f0064bb7fa4b7589ab076a0f87c4b9
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96039 (2014)
Periodic oscillations play an important role in many biomedical systems. Proper functioning of biological systems that respond to periodic signals requires the ability to synchronize with the periodic excitation. For example, the sleep/wake cycle is
Externí odkaz:
https://doaj.org/article/fdf4623d101b4f778e8a8723f2ba2a2f
Publikováno v:
IEEE Transactions on Automatic Control. 67:4629-4644
Publikováno v:
IEEE Transactions on Automatic Control. 67:4994-5001
The flow of contracting systems contracts 1-dimensional parallelotopes, i.e., line segments, at an exponential rate. One reason for the usefulness of contracting systems is that many interconnections of contracting sub-systems yield an overall contra