Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael Marchioli"'
Autor:
Anthony DiNatale, Asurayya Worrede, Waleed Iqbal, Michael Marchioli, Allison Toth, Martin Sjöström, Xiaolin Zhu, Eva Corey, Felix Y. Feng, Wanding Zhou, Alessandro Fatatis
Publikováno v:
Cancer Res Commun
We report the inverse association between the expression of androgen receptor (AR) and IL1β in a cohort of patients with metastatic castration-resistant prostate cancer. We also discovered that AR represses the IL1β gene by binding an androgen resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dacb0f69e03eb0c1488af806bbf0b076
https://doi.org/10.1158/2767-9764.crc-22-0262
https://doi.org/10.1158/2767-9764.crc-22-0262
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
Expression of CMV-AR and TRE-AR constructs in PC3-ML cells, confirmed at the transcript level for both (a) and at the protein level for the TRE-AR following addition of doxycycline to the culture medium (b).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee84f238b7723f869523c8c0bf3af55
https://doi.org/10.1158/2767-9764.22361305
https://doi.org/10.1158/2767-9764.22361305
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
PC3-ML cells show no difference in luciferase activity between the wild-type promoter and the AREΔ IL-1β promoter, in which the ARE half-site located at -576 was removed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723e0c0279caaba2a83bbf9dd0af546c
https://doi.org/10.1158/2767-9764.22361299
https://doi.org/10.1158/2767-9764.22361299
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
PC3-ML cells transduced with an inducible AR-overexpression construct showed strong mitigation of IL-1β expression (a) and secretion (b), as compared to both wild type, non-transduced cells and transduced cells without doxycycline exposure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bb3884e2ed311e443924cc61e25c64
https://doi.org/10.1158/2767-9764.22361302
https://doi.org/10.1158/2767-9764.22361302
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
Primer sequences used for ChIP assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80daa869014a1d8722bd729da127d9eb
https://doi.org/10.1158/2767-9764.22361296.v1
https://doi.org/10.1158/2767-9764.22361296.v1
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
C4-2B cells exposed to Enzalutamide show a dose-dependent(a) and time- dependent increase in IL-1β expression (b). Removal of enzalutamide after a 15-day treatment resulted in a return of IL-1β expression to control (undetectable) levels (c). Same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8deb8a325f052009cdd1fa177416c3bd
https://doi.org/10.1158/2767-9764.22361308
https://doi.org/10.1158/2767-9764.22361308
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
We report the inverse association between the expression of androgen receptor (AR) and IL1β in a cohort of patients with metastatic castration-resistant prostate cancer. We also discovered that AR represses the IL1β gene by binding an androgen resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1180c9fd179715198a0abbf3b04c86de
https://doi.org/10.1158/2767-9764.c.6487576
https://doi.org/10.1158/2767-9764.c.6487576
Autor:
Alessandro Fatatis, Wanding Zhou, Felix Y. Feng, Eva Corey, Xiaolin Zhu, Martin Sjöström, Allison Toth, Michael Marchioli, Waleed Iqbal, Asurayya Worrede, Anthony DiNatale
Whole genome bisulfite sequencing conducted on a subset of patients with low AR activity and low IL-1β expression revealed 346 CpG sites spanning the IL-1β promoter and gene body on chromosome 2, of which 34 showed significant differences in methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b4035446891069d1f7758ca8a6e5e5
https://doi.org/10.1158/2767-9764.22341826
https://doi.org/10.1158/2767-9764.22341826
Autor:
Anthony DiNatale, Ramanpreet Kaur, Chen Qian, Jieyi Zhang, Michael Marchioli, Darin Ipe, Maria Castelli, Chris M. McNair, Gaurav Kumar, Olimpia Meucci, Alessandro Fatatis
Publikováno v:
Oncogene
Metastasis-initiating cells (MICs) display stem cell-like features, cause metastatic recurrences and defy chemotherapy, which leads to patients’ demise. Here we show that prostate and breast cancer patients harbor contingents of tumor cells with hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c2970e5e1b58474adda6f3dc2d996c
https://doi.org/10.1038/s41388-021-02174-w
https://doi.org/10.1038/s41388-021-02174-w
Autor:
Jieyi Zhang, Anthony DiNatale, Ramanpreet Kaur, Qian Chen, Michael Marchioli, Darin Ipe, Maria Castelli, Christopher McNair, Gaurav Kumar, Olimpia Meucci, Alessandro Fatatis
Publikováno v:
Cancer Research. 82:2193-2193
Metastasis-initiating cells (MICs) display stem cell-like features, cause metastatic recurrences and defy chemotherapy, which leads to patients’ demise. Here we show that prostate and breast cancer patients harbor contingents of tumor cells with hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e26ad93d58ae88e07eae230ce5ad4fb9
https://doi.org/10.1158/1538-7445.am2022-2193
https://doi.org/10.1158/1538-7445.am2022-2193