Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Michael M.-C. Lo"'
Publikováno v:
Advanced Synthesis & Catalysis. 361:5140-5143
Autor:
Brent R. Whitehead, Michael M.-C. Lo, Amjad Ali, Min K. Park, Scott B. Hoyt, Yusheng Xiong, Jiaqiang Cai, Emma Carswell, Andrew Cooke, John MacLean, Paul Ratcliffe, John Robinson, D. Jonathan Bennett, Joseph A. Clemas, Tom Wisniewski, Mary Struthers, Doris Cully, Douglas J. MacNeil
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:143-146
This invention relates to triazolopyridyl compounds of the structural formula: [Formula should be inserted here] or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldoster
Publikováno v:
Tetrahedron. 62:11343-11349
This report describes the synthesis and an application of a new planar-chiral Lewis acid based on a 1,2-azaborolyl framework. The enantiopure complex is generated through an intriguing kinetic resolution by a chiral nucleophile. Imines bind in excell
Publikováno v:
Angewandte Chemie. 117:2289-2292
Autor:
Michael M.-C. Lo, and Jerry M. Allen, Stéphane Bellemin-Laponnaz, Gregory C. Fu, Thomas H. Peterson
Publikováno v:
Organometallics. 20:3453-3458
Several C2-symmetric bis(phospholyl) adducts of group 4 metals, including the first example of an η5-phospholyl complex of hafnium, have been synthesized and structurally characterized. These complexes undergo rac/meso isomerization in a process tha
Autor:
Michael M.-C. Lo, Gregory C. Fu
Publikováno v:
Tetrahedron. 57:2621-2634
A planar-chiral, C2-symmetric bisazaferrocene ligand is shown to control the stereochemistry of Cu(I)-catalyzed ring expansions of oxetanes to tetrahydrofurans.
Publikováno v:
The Journal of Organic Chemistry. 62:6316-6321
In an effort to further optimize and to define the structural limitations of the nitrile aldol reaction, several studies were undertaken. Lithiated phenylacetonitrile 1 was demonstrated to exhibit ...
Publikováno v:
The Journal of Organic Chemistry. 60:7511-7517
Publikováno v:
Angewandte Chemie International Edition. 41:174-176
Autor:
Marc L. Reitman, Xiao-Ming Guan, Linus S. Lin, Ravi P. Nargund, Oksana C. Palyha, Harry R. Chobanian, Michael M.-C. Lo, Yanqing Kan, Kathryn A. Lyons, Theresa M. Kelly, Jasminka Dragovic
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(7)
Bombesin receptor subtype-3 (BRS-3) is an orphan G-protein coupled receptor belonging to the subfamily of bombesin-like receptors. BRS-3 is implicated in the development of obesity and diabetes. We report here small-molecule agonists that are based o