598: LOSS OF PTPN23 IN THE INTESTINAL EPITHELIUM RESULTS IN EPITHELIAL HYPERPROLIFERATION AND LETHAL DIARRHEA IN A MICROBIOTA DEPENDENT MANNER

Autor: Marianne Spalinger, Rocio Sanchez Alvarez, Claudia Gottier, Ana Montalban-Arques, Marlene Schwarzfischer, Anna Niechcial, Michael M. Scharl

Publikováno v: Gastroenterology. 162:S-149

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e5abcf19a159affef621ff31501bb2e
https://doi.org/10.1016/s0016-5085(22)60360-3

217: PTPN2 LOSS-OF-FUNCTION REDUCES VITAMIN B12 LEVELS IN GENOTYPED CROHN'S DISEASE PATIENTS AND INTESTINAL BRUSH BORDER EXPRESSION OF THE B12 TRANSPORTER, CUBILIN, IN MICE

Autor: Salomon M. Manz, Vinicius Canale, Meli'sa S. Crawford, Pritha Chaterjee, Andy Lei, Alina N. Santos, Ali Shawki, Marianne Spalinger, Michael M. Scharl, Declan F. McCole

Publikováno v: Gastroenterology. 162:S-39

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c977b01663e6730d48cfc8c53e2b2149
https://doi.org/10.1016/s0016-5085(22)60097-0

Impact of Nanoplastic Particles on Macrophage Inflammation and Intestinal Health in a Mouse Model of Inflammatory Bowel Disease.

Autor: Schwarzfischer M; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Ruoss TS; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Niechcial A; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Lee SS; Scientific Center for Optical and Electron Microscopy, ETH Zurich, 8093 Zurich, Switzerland.; Institute of Biochemistry, ETH Zurich, 8093 Zurich, Switzerland., Wawrzyniak M; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Laimbacher A; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Atrott K; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Manzini R; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Wilmink M; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Linzmeier L; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Morsy Y; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Lang S; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Rogler G; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Kaegi R; Department Process Engineering, Swiss Federal Institute of Aquatic Science and Technology (Eawag), 8600 Dübendorf, Switzerland., Scharl M; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Spalinger MR; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.

Publikováno v: Nanomaterials (Basel, Switzerland) [Nanomaterials (Basel)] 2024 Aug 15; Vol. 14 (16). Date of Electronic Publication: 2024 Aug 15.

Longitudinal microbiome investigation throughout prion disease course reveals pre- and symptomatic compositional perturbations linked to short-chain fatty acid metabolism and cognitive impairment in mice.

Autor: Losa M; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.; Institute of Neuropathology, University Hospital Zurich, University of Zurich, Zürich, Switzerland., Morsy Y; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland., Emmenegger M; Institute of Neuropathology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.; Institute of Clinical Immunology, University Hospital Basel, Basel, Switzerland., Manz SM; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland., Schwarz P; Institute of Neuropathology, University Hospital Zurich, University of Zurich, Zürich, Switzerland., Aguzzi A; Institute of Neuropathology, University Hospital Zurich, University of Zurich, Zürich, Switzerland., Scharl M; Department of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.

Publikováno v: Frontiers in microbiology [Front Microbiol] 2024 Jun 11; Vol. 15, pp. 1412765. Date of Electronic Publication: 2024 Jun 11 (Print Publication: 2024).

Microbiota Manipulation as an Emerging Concept in Cancer Therapy.

Autor: Spalinger MR; Department for Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland., Scharl M; Department for Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland.

Publikováno v: Visceral medicine [Visc Med] 2024 Feb; Vol. 40 (1), pp. 2-11. Date of Electronic Publication: 2023 Dec 12.