Development and validation of next generation sequencing based 35-gene hereditary cancer panel

Autor: Wing Chan, Mianne Lee, Zhen Xuan Yeo, Dingge Ying, Keith A. Grimaldi, Craig Pickering, Michael M. S. Yang, Senthil K. Sundaram, Lawrence C. H. Tzang

Publikováno v: Hereditary Cancer in Clinical Practice, Vol 18, Iss 1, Pp 1-8 (2020)

Abstract Background Understanding the genetic basis of cancer risk is a major international endeavor. The emergence of next-generation sequencing (NGS) in late 2000’s has further accelerated the discovery of many cancer susceptibility genes. The us

Externí odkaz: https://doaj.org/article/5fbb086b5cdc433cadb931c41fb52625

Gender-specific modulation of immune system complement gene expression in marine medaka Oryzias melastigma following dietary exposure of BDE-47

Autor: Michael H.W. Lam, Amy C. C. Fong, Rudolf S.S. Wu, Alice K.Y. Chan, Elva N. Y. Lei, Jun Bo, Helmut Segner, Doris W.T. Au, Jason P. van de Merwe, Roy R. Ye, Jae-Seong Lee, Michael M. S. Yang, Chris K. C. Wong

Publikováno v: Environmental Science and Pollution Research International
Ye, Roy R.; Lei, Elva N. Y.; Lam, Michael H. W.; Chan, Alice K. Y.; Bo, Jun; van de Merwe, Jason P.; Fong, Amy C. C.; Yang, Michael M. S.; Lee, J. S.; Segner, Helmut E.; Wong, Chris K. C.; Wu, Rudolf S. S.; Au, Doris W. T. (2012). Gender-specific modulation of immune system complement gene expression in marine medaka Oryzias melastigma following dietary exposure of BDE-47. Environmental science and pollution research, 19(7), pp. 2477-2487. Springer 10.1007/s11356-012-0887-z
Environmental Science and Pollution Research

BDE-47 is one of the most widely found congeners of PBDEs in marine environments. The potential immunomodulatory effects of BDE-47 on fish complement system were studied using the marine medaka Oryzias melastigma as a model fish. Three-month-old O. m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116fdcb3cf8997eb989236cbcea5baba
https://doi.org/10.1007/s11356-012-0887-z