Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Michael M. P. J. Verbiest"'
Autor:
Shatavisha Dasgupta, Patricia C. Ewing-Graham, Sigrid M. A. Swagemakers, Thierry P. P. van den Bosch, Peggy N. Atmodimedjo, Michael M. P. J. Verbiest, Marit de Haan, Helena C. van Doorn, Peter J. van der Spek, Senada Koljenović, Folkert J. van Kemenade
Publikováno v:
Cancers, Vol 13, Iss 14, p 3580 (2021)
DNA methylation is the most widely studied mechanism of epigenetic modification, which can influence gene expression without alterations in DNA sequences. Aberrations in DNA methylation are known to play a role in carcinogenesis, and methylation prof
Externí odkaz:
https://doaj.org/article/a688be0a377145fba6a95d6e5b83e043
Autor:
Lisette Stolk, Marieke I. Bouwland-Both, N. H. van Mil, Michael M. P. J. Verbiest, Paul H. C. Eilers, Huiping Zhu, Lucina Suarez, André G. Uitterlinden, Régine P. M. Steegers-Theunissen
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/9131e788d8ff424b9668ed961caa80ac
Autor:
Jard H. de Vries, Danuta Piniewska-Róg, Pascal P. Arp, Vivian Kalamara, Thomas J. Parsons, Athina Vidaki, André G. Uitterlinden, Michael M. P. J. Verbiest, Daniel Kling, Manfred Kayser
Publikováno v:
Forensic Science International: Genetics, 56:102625. Elsevier Ireland Ltd
Single nucleotide polymorphism (SNP) data generated with microarray technologies have been used to solve murder cases via investigative leads obtained from identifying relatives of the unknown perpetrator included in accessible genomic databases, ref
Autor:
Marit de Haan, Senada Koljenović, Peter J. van der Spek, Folkert J. van Kemenade, Peggy N. Atmodimedjo, Thierry P P van den Bosch, Michael M. P. J. Verbiest, Sigrid M. A. Swagemakers, Shatavisha Dasgupta, Patricia C. Ewing-Graham, Helena C. van Doorn
Publikováno v:
Cancers, Vol 13, Iss 3580, p 3580 (2021)
Cancers, 13(14):3580. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers
Volume 13
Issue 14
Cancers, 13(14):3580. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers
Volume 13
Issue 14
Simple Summary Vulvar squamous cell carcinoma (VSCC) is the most common form of vulvar malignancy, and its incidence has increased in recent years. For better diagnosis and prognostication, and to expand available treatment options, molecular charact
Autor:
Peter J. van der Spek, Kim P.J. Wijnands, Jun Chen, Willem A. Helbing, Adriana C. Gittenberger-de Groot, Michael M. P. J. Verbiest, André G. Uitterlinden, Xihong Lin, Régine P.M. Steegers-Theunissen, Liming Liang
Publikováno v:
Epigenomics, 9(3), 241-251. Future Medicine Ltd.
Aim: Congenital heart diseases are the most common birth defects worldwide and leading cause of infant mortality. The perimembranous ventricular septal defect is most prevalent. Epigenetics may provide an underlying mechanism of the gene–environmen
Autor:
Andrea P. Cortes Hidalgo, Charlotte A.M. Cecil, Henning Tiemeier, Jana Nano, Wichor M. Bramer, Oscar H. Franco, Michael M. P. J. Verbiest, Taulant Muka, Lorenza Dall’Aglio
Publikováno v:
Dall'Aglio, L, Muka, T, Cecil, C, Bramer, W, Verbiest, M M P J, Nano, J, Cortes Hidalgo, A, Franco, O H & Tiemeier, H 2018, ' The role of epigenetic modifications in neurodevelopmental disorders : A systematic review ', Neuroscience and Biobehavioral Reviews . https://doi.org/10.1016/j.neubiorev.2018.07.011
Neuroscience and Biobehavioral Reviews, 94, 17-30. Elsevier Ltd.
Neuroscience and Biobehavioral Reviews, 94, 17-30. Elsevier Ltd.
Epigenetic processes have been suggested as key mechanisms in the etiology of neurodevelopmental disorders. This systematic review summarizes the current evidence for an association between epigenetics and Autism Spectrum Disorder (ASD) and Attention
Autor:
Marleen M.J. van Greevenbroek, Erik W. van Zwet, Jeroen van Rooij, Wibowo Arindrarto, Tianxiao Huan, Marijn Verkerk, Allan C. Just, Cisca Wijmenga, Coen D.A. Stehouwer, Cornelia M. van Duijn, Coleen M. Damcott, Symen Ligthart, Dorret I. Boomsma, Cristina Menni, Hailiang Mei, Guosheng Zhang, Eric Boerwinkle, Diana van Heemst, Albert Hofman, Casper G. Schalkwijk, Jordana T. Bell, Carla J.H. van der Kallen, John M. Starr, Yucheng Jia, Andrea A. Baccarelli, Jeffrey R. O'Connell, Joyce B. C van Meurs, Steve Horvath, Allan F. McRae, Leonard H. van den Berg, Walter Palmas, Szymon M. Kielbasa, Freerk van Dijk, Stephen Turner, Sharon L.R. Kardia, Donna K. Arnett, Devin Absher, James D. Stewart, Jerome I. Rotter, Jouke J. Hottenga, Rahul Gondalia, Jan Bot, Joris Deelen, René Pool, Tomáš Paus, Yii-Der Ida Chen, Peter A.C. ’t Hoen, Thomas H. Mosley, René Luijk, Zdenka Pausova, Ettje F. Tigchelaar, Bastiaan T. Heijmans, André G. Uitterlinden, P. Mila Jhamai, Eric A. Whitsel, Alanna C. Morrison, Patrick Deelen, Lude Franke, Riccardo E. Marioni, Chunyu Liu, Rick Jansen, Marc Jan Bonder, J. H. Veldink, Xiuqing Guo, Oscar H. Franco, Yongmei Liu, Nona Sotoodehnia, Nico Lakenberg, Joel Schwartz, Daniel Levy, Catriona Syme, May E. Montasser, Irene Nooren, Elias Salfati, Michael M. Mendelson, Abbas Dehghan, Tim D. Spector, Jan Bressler, Jennifer A. Smith, Matthijs Moed, H. Eka D. Suchiman, Martijn Vermaat, Alan R. Shuldiner, Michael M. P. J. Verbiest, A Isaacs, Dasha V. Zhernakova, Jennifer A. Brody, Alexandra Zhernakova, Wei Zhao, Marian Beekman, Ian J. Deary, Maarten van Iterson, Min A. Jhun, Michiel van Galen, Weihua Guan, Jincheng Shen, Stella Aslibekyan, Myriam Fornage, Joyce B. J. van Meurs, Pantel S. Vokonas, Bruce M. Psaty, Melissa A. Richard, Peter Van ‘t Hof, Yun Li, Morris A. Swertz, Themistocles L. Assimes, P. Eline Slagboom, Jenny van Dongen, Pei-Chien Tsai, Lifang Hou, Ruud van der Breggen, Marguerite R. Irvin, Joshua C. Bis
Publikováno v:
Richard, M A, Huan, T, Ligthart, S, Gondalia, R, Jhun, M A, Brody, J A, Irvin, M R, Marioni, R, Shen, J, Tsai, P-C, Montasser, M E, Jia, Y, Syme, C, Salfati, E L, Boerwinkle, E, Guan, W, Mosley, T H, Bressler, J, Morrison, A C, Liu, C, Mendelson, M M, Uitterlinden, A G, van Meurs, J B, Franco, O H, Zhang, G, Li, Y, Stewart, J D, Bis, J C, Psaty, B M, Chen, Y-D I, Kardia, S L R, Zhao, W, Turner, S T, Absher, D, Aslibekyan, S, Starr, J M, McRae, A F, Hou, L, Just, A C, Schwartz, J D, Vokonas, P S, Menni, C, Spector, T D, Shuldiner, A, Damcott, C M, Rotter, J I, BIOS Consortium, Boomsma, D I, Pool, R, van Dongen, J & Hottenga, J J 2017, ' DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation ', American Journal of Human Genetics, vol. 101, no. 6, pp. 888-902 . https://doi.org/10.1016/j.ajhg.2017.09.028
American Journal of Human Genetics, 101(6), 888-902. Cell Press
American journal of human genetics, vol 101, iss 6
American Journal of Human Genetics, 101(6), 888-902
Richard, M A, Huan, T, Ligthart, S, Gondalia, R, Jhun, M A, Brody, J A, Irvin, M R, Marioni, R, Shen, J, Tsai, P-C, Montasser, M E, Jia, Y, Syme, C, Salfati, E L, Boerwinkle, E, Guan, W, Mosley, T H, Bressler, J, Morrison, A C, Liu, C, Mendelson, M M, Uitterlinden, A G, van Meurs, J B, Franco, O H, Zhang, G, Li, Y, Stewart, J D, Bis, J C, Psaty, B M, Chen, Y-D I, Kardia, S L R, Zhao, W, Turner, S T, Absher, D, Aslibekyan, S, Starr, J M, McRae, A F, Hou, L, Just, A C, Schwartz, J D, Vokonas, P S, Menni, C, Spector, T D, Shuldiner, A, Damcott, C M, Rotter, J I, Palmas, W, Liu, Y & Smith, J A & Deary, I J 2017, ' DNA methylation analysis identifies loci for blood pressure regulation ', American Journal of Human Genetics, vol. 101, no. 6, pp. 888-902 . https://doi.org/10.1016/j.ajhg.2017.09.028
American Journal of Human Genetics, 101(6), 888-902. Cell Press
American journal of human genetics, vol 101, iss 6
American Journal of Human Genetics, 101(6), 888-902
Richard, M A, Huan, T, Ligthart, S, Gondalia, R, Jhun, M A, Brody, J A, Irvin, M R, Marioni, R, Shen, J, Tsai, P-C, Montasser, M E, Jia, Y, Syme, C, Salfati, E L, Boerwinkle, E, Guan, W, Mosley, T H, Bressler, J, Morrison, A C, Liu, C, Mendelson, M M, Uitterlinden, A G, van Meurs, J B, Franco, O H, Zhang, G, Li, Y, Stewart, J D, Bis, J C, Psaty, B M, Chen, Y-D I, Kardia, S L R, Zhao, W, Turner, S T, Absher, D, Aslibekyan, S, Starr, J M, McRae, A F, Hou, L, Just, A C, Schwartz, J D, Vokonas, P S, Menni, C, Spector, T D, Shuldiner, A, Damcott, C M, Rotter, J I, Palmas, W, Liu, Y & Smith, J A & Deary, I J 2017, ' DNA methylation analysis identifies loci for blood pressure regulation ', American Journal of Human Genetics, vol. 101, no. 6, pp. 888-902 . https://doi.org/10.1016/j.ajhg.2017.09.028
Genome-wide association studies have identified hundreds of genetic variants associated with blood pressure (BP), but sequence variation accounts for a small fraction of the phenotypic variance. Epigenetic changes may alter the expression of genes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f9a42b3b8c7e77be3a72983127a651
https://hdl.handle.net/1871.1/51b0b3db-be77-422d-8855-2ee913d5b802
https://hdl.handle.net/1871.1/51b0b3db-be77-422d-8855-2ee913d5b802
Autor:
Floor V. A. van Oort, James J. Hudziak, Frank C. Verhulst, Albertine J. Oldehinkel, Harriëtte Riese, Michael M. P. J. Verbiest, Lisette J. van der Knaap
Publikováno v:
Psychosomatic Medicine, 77(3), 246-255. Lippincott Williams & Wilkins
Psychosomatic Medicine, 77(3), 246-255. LIPPINCOTT WILLIAMS & WILKINS
Psychosomatic Medicine, 77(3), 246-255. LIPPINCOTT WILLIAMS & WILKINS
Objectives Adverse life events increase vulnerability to affective disorders later in life, possibly mediated by methylation of the serotonin transporter gene (SLC6A4). We investigated the relationship of SLC6A4 methylation with various types of adve
Autor:
Peter Van ‘t Hof, Erik W. van Zwet, Matthijs Moed, Jeroen van Rooij, Joris Deelen, Freerk van Dijk, Nico Lakenberg, Cisca Wijmenga, André G. Uitterlinden, Rick Jansen, Maarten van Iterson, Dasha V. Zhernakova, Szymon M. Kielbasa, Martijn Vermaat, Marleen J. van Greevenbroek, Hailiang Mei, Cornelia M. van Duijn, René Pool, Jan Bot, Lude Franke, Sasha Zhernakova, Michiel van Galen, H. Eka D. Suchiman, Morris A. Swertz, Marc Jan Bonder, Bert A. Hofman, Wibowo Arindrarto, Joyce B. J. van Meurs, Jouke J. Hottenga, Coen D.A. Stehouwer, Jenny van Dongen, Michael M. P. J. Verbiest, René Luijk, P. Eline Slagboom, Patrick Deelen, Dorret I. Boomsma, Jan H. Veldink, Leonard H. van den Berg, Diana van Heemst, Aaron Isaacs, Marijn Verkerk, Peter A C 't Hoen, Ruud van der Breggen, Casper G. Schalkwijk, Ettje F. Tigchelaar, Peter Bram 't Hoen, Marian Beekman, Carla J.H. van der Kallen, Bastiaan T. Heijmans, P. Mila Jhamai, Irene Nooren
Publikováno v:
Genome Biology, 18(1):19. Springer Verlag
Genome Biology, 18(1):19. BioMed Central Ltd.
van Iterson, M, van Zwet, E W, Heijmans, B T, ’t Hoen, P A C, van Meurs, J B J, Jansen, R, Franke, L, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, Van Greevenbroek, M J, Stehouwer, C D A, van der Kallen, C J H, Schalkwijk, C G, Wijmenga, C, Zhernakova, S, Tigchelaar, E F, Eline Slagboom, P, Beekman, M, Deelen, J, van Heemst, D, Veldink, J H, van den Berg, L H, van Duijn, C M, Hofman, B A, Isaacs, A, Uitterlinden, A G, Jhamai, P M, Verbiest, M, Suchiman, H E D, Verkerk, M, van der Breggen, R, van Rooij, J, Lakenberg, N, Mei, H, van Galen, M, Bot, J, Zhernakova, D V, van 't Hof, P, Deelen, P, Nooren, I, Moed, M, Vermaat, M, Luijk, R, Bonder, M J, van Dijk, F, Arindrarto, W, Kielbasa, S M, Swertz, M A & 't Hoen, P B 2017, ' Controlling bias and inflation in epigenome-and transcriptome-wide association studies using the empirical null distribution ', Genome Biology, vol. 18, no. 1, 19 . https://doi.org/10.1186/s13059-016-1131-9
Genome Biology, 18
van Iterson, M, van Zwet, E W, Heijmans, B T, 't Hoen, P A C, van Meurs, J, Jansen, R, Franke, L, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, van Greevenbroek, M M J, Stehouwer, C D A, van der Kallen, C J H, Schalkwijk, C G, Wijmenga, C, Zhernakova, S, Tigchelaar, E F, Eline Slagboom, P, Beekman, M, Deelen, J, van Heemst, D, Veldink, J H, van den Berg, L H, van Duijn, C M, Hofman, B A, Isaacs, A, Uitterlinden, A G, Jhamai, P M, Verbiest, M, Suchiman, H E D, Verkerk, M, van der Breggen, R, van Rooij, J, Lakenberg, N, Mei, H, van Galen, M, Bot, J, Zhernakova, D V, van 't Hof, P, Deelen, P, Nooren, I, Moed, M, Vermaat, M, Luijk, R, Bonder, M J, van Dijk, F, Arindrarto, W, Kielbasa, S M, Swertz, M A & 't Hoen, P B 2017, ' Controlling bias and inflation in epigenome-and transcriptome-wide association studies using the empirical null distribution ', Genome Biology, vol. 18, no. 1, 19 . https://doi.org/10.1186/s13059-016-1131-9
Genome Biology
Genome Biology, 18(1):19. BioMed Central Ltd.
van Iterson, M, van Zwet, E W, Heijmans, B T, ’t Hoen, P A C, van Meurs, J B J, Jansen, R, Franke, L, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, Van Greevenbroek, M J, Stehouwer, C D A, van der Kallen, C J H, Schalkwijk, C G, Wijmenga, C, Zhernakova, S, Tigchelaar, E F, Eline Slagboom, P, Beekman, M, Deelen, J, van Heemst, D, Veldink, J H, van den Berg, L H, van Duijn, C M, Hofman, B A, Isaacs, A, Uitterlinden, A G, Jhamai, P M, Verbiest, M, Suchiman, H E D, Verkerk, M, van der Breggen, R, van Rooij, J, Lakenberg, N, Mei, H, van Galen, M, Bot, J, Zhernakova, D V, van 't Hof, P, Deelen, P, Nooren, I, Moed, M, Vermaat, M, Luijk, R, Bonder, M J, van Dijk, F, Arindrarto, W, Kielbasa, S M, Swertz, M A & 't Hoen, P B 2017, ' Controlling bias and inflation in epigenome-and transcriptome-wide association studies using the empirical null distribution ', Genome Biology, vol. 18, no. 1, 19 . https://doi.org/10.1186/s13059-016-1131-9
Genome Biology, 18
van Iterson, M, van Zwet, E W, Heijmans, B T, 't Hoen, P A C, van Meurs, J, Jansen, R, Franke, L, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, van Greevenbroek, M M J, Stehouwer, C D A, van der Kallen, C J H, Schalkwijk, C G, Wijmenga, C, Zhernakova, S, Tigchelaar, E F, Eline Slagboom, P, Beekman, M, Deelen, J, van Heemst, D, Veldink, J H, van den Berg, L H, van Duijn, C M, Hofman, B A, Isaacs, A, Uitterlinden, A G, Jhamai, P M, Verbiest, M, Suchiman, H E D, Verkerk, M, van der Breggen, R, van Rooij, J, Lakenberg, N, Mei, H, van Galen, M, Bot, J, Zhernakova, D V, van 't Hof, P, Deelen, P, Nooren, I, Moed, M, Vermaat, M, Luijk, R, Bonder, M J, van Dijk, F, Arindrarto, W, Kielbasa, S M, Swertz, M A & 't Hoen, P B 2017, ' Controlling bias and inflation in epigenome-and transcriptome-wide association studies using the empirical null distribution ', Genome Biology, vol. 18, no. 1, 19 . https://doi.org/10.1186/s13059-016-1131-9
Genome Biology
We show that epigenome- and transcriptome-wide association studies (EWAS and TWAS) are prone to significant inflation and bias of test statistics, an unrecognized phenomenon introducing spurious findings if left unaddressed. Neither GWAS-based method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c64cec6e93f81a6586330768430c9b
https://hdl.handle.net/1887/114294
https://hdl.handle.net/1887/114294
Autor:
André G. Uitterlinden, Marinus H. van IJzendoorn, Liesbeth Duijts, Marieke I. Bouwland-Both, Paul H. C. Eilers, Vincent W. V. Jaddoe, Henning Tiemeier, Régine P.M. Steegers-Theunissen, Catharina P. Tolhoek, Nina H. van Mil, Albert Hofman, Johan C. de Jongste, Lisette Stolk, Michael M. P. J. Verbiest, Bastiaan T. Heijmans, Eric A.P. Steegers
Publikováno v:
Clinical Epigenetics, 7
Clinical Epigenetics
Clinical Epigenetics, 7(1):83. BioMed Central Ltd.
Clinical Epigenetics
Clinical Epigenetics, 7(1):83. BioMed Central Ltd.
Background Deleterious effects of prenatal tobacco smoking on fetal growth and newborn weight are well-established. One of the proposed mechanisms underlying this relationship is alterations in epigenetic programming. We selected 506 newborns from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669a974f1e4326884bafc1261651d54f
http://hdl.handle.net/1887/105800
http://hdl.handle.net/1887/105800