Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Michael M. Lizardo"'
Autor:
Renata Scopim-Ribeiro, Michael M. Lizardo, Hai-Feng Zhang, Anne-Chloé Dhez, Chistopher S. Hughes, Poul H. Sorensen
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Ewing sarcoma (EwS) is a highly malignant bone and soft tissue tumor primarily affecting children and young adults. While most patients initially respond well to conventional front-line therapy, frequent metastasis results in poor 5-year overall surv
Externí odkaz:
https://doaj.org/article/07b9de9743a241a6915fee7b0ab6f226
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Osteosarcoma is a malignant primary tumor of bone, arising from transformed progenitor cells with osteoblastic differentiation and osteoid production. While categorized as a rare tumor, most patients diagnosed with osteosarcoma are adolescents in the
Externí odkaz:
https://doaj.org/article/b6f1a0df81d247859fdae0aceac0e9a5
Autor:
Michael M. Lizardo, James J. Morrow, Tyler E. Miller, Ellen S. Hong, Ling Ren, Arnulfo Mendoza, Charles H. Halsey, Peter C. Scacheri, Lee J. Helman, Chand Khanna
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 11, Pp 699-710 (2016)
Metastasis is the cause of more than 90% of all cancer deaths. Despite this fact, most anticancer therapeutics currently in clinical use have limited efficacy in treating established metastases. Here, we identify the endoplasmic reticulum chaperone p
Externí odkaz:
https://doaj.org/article/1cec0555a1e7493ba110c2223f943639
Autor:
Poul H. Sorensen, Dimiter S. Dimitrov, Olivier Delattre, Gregg B. Morin, Li-Yan Xu, Rimas J. Orentas, Ramon I. Klein Geltink, Seth J. Parker, Mads Daugaard, Anne Steino, Amy Li, Sonia H.Y. Kung, Jonathan K.M. Lim, Sofya Langman, Anne-Chloe Dhez, Colin A. Hammond, Renata Scopim-Ribeiro, Taras Shyp, Shane Colborne, Htoo Zarni Oo, Michael M. Lizardo, Maj Sofie Ørum-Madsen, Xiaojun Li, Gian Luca Negri, Alberto Delaidelli, Anna Prudova, Hongwei Cheng, Amal M. El-Naggar, Didier Surdez, Jian-Zhong He, Wei Li, Christopher S. Hughes, Hai-Feng Zhang
Supplementary Data from Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e6166f1c594b2194af8072175d86fe
https://doi.org/10.1158/2159-8290.22540877
https://doi.org/10.1158/2159-8290.22540877
Autor:
Poul H. Sorensen, Dimiter S. Dimitrov, Olivier Delattre, Gregg B. Morin, Li-Yan Xu, Rimas J. Orentas, Ramon I. Klein Geltink, Seth J. Parker, Mads Daugaard, Anne Steino, Amy Li, Sonia H.Y. Kung, Jonathan K.M. Lim, Sofya Langman, Anne-Chloe Dhez, Colin A. Hammond, Renata Scopim-Ribeiro, Taras Shyp, Shane Colborne, Htoo Zarni Oo, Michael M. Lizardo, Maj Sofie Ørum-Madsen, Xiaojun Li, Gian Luca Negri, Alberto Delaidelli, Anna Prudova, Hongwei Cheng, Amal M. El-Naggar, Didier Surdez, Jian-Zhong He, Wei Li, Christopher S. Hughes, Hai-Feng Zhang
Supplementary Table from Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5f6db3565e8f004bc82ed28ead0aca
https://doi.org/10.1158/2159-8290.22540874.v1
https://doi.org/10.1158/2159-8290.22540874.v1
Autor:
Poul H. Sorensen, Dimiter S. Dimitrov, Olivier Delattre, Gregg B. Morin, Li-Yan Xu, Rimas J. Orentas, Ramon I. Klein Geltink, Seth J. Parker, Mads Daugaard, Anne Steino, Amy Li, Sonia H.Y. Kung, Jonathan K.M. Lim, Sofya Langman, Anne-Chloe Dhez, Colin A. Hammond, Renata Scopim-Ribeiro, Taras Shyp, Shane Colborne, Htoo Zarni Oo, Michael M. Lizardo, Maj Sofie Ørum-Madsen, Xiaojun Li, Gian Luca Negri, Alberto Delaidelli, Anna Prudova, Hongwei Cheng, Amal M. El-Naggar, Didier Surdez, Jian-Zhong He, Wei Li, Christopher S. Hughes, Hai-Feng Zhang
Cancer cells must overcome anoikis (detachment-induced death) to successfully metastasize. Using proteomic screens, we found that distinct oncoproteins upregulate IL1 receptor accessory protein (IL1RAP) to suppress anoikis. IL1RAP is directly induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8bdb1c5f12ead9674106bc25ce091c7
https://doi.org/10.1158/2159-8290.c.6549488.v1
https://doi.org/10.1158/2159-8290.c.6549488.v1
Autor:
Chand Khanna, Peter C. Scacheri, Timothy M. Fan, Ming Zhou, Daniel L. Gustafson, Ryan J. Hansen, Timothy J. Waybright, Ling Ren, Michael M. Lizardo, Allyson Koyen, Arnulfo Mendoza, James J. Morrow
Legends for Supplementary Tables and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942fcd3e3a674bad82006e0fc7edd911
https://doi.org/10.1158/1078-0432.22468887
https://doi.org/10.1158/1078-0432.22468887
Autor:
Chand Khanna, Peter C. Scacheri, Timothy M. Fan, Ming Zhou, Daniel L. Gustafson, Ryan J. Hansen, Timothy J. Waybright, Ling Ren, Michael M. Lizardo, Allyson Koyen, Arnulfo Mendoza, James J. Morrow
Purpose: To successfully metastasize, tumor cells must respond appropriately to biological stressors encountered during metastatic progression. We sought to test the hypothesis that enhanced efficiency of mRNA translation during periods of metastatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb01450fc974ab0d0990de07585b753
https://doi.org/10.1158/1078-0432.c.6527085.v1
https://doi.org/10.1158/1078-0432.c.6527085.v1
Autor:
Chand Khanna, Peter C. Scacheri, Timothy M. Fan, Ming Zhou, Daniel L. Gustafson, Ryan J. Hansen, Timothy J. Waybright, Ling Ren, Michael M. Lizardo, Allyson Koyen, Arnulfo Mendoza, James J. Morrow
Summary of BONCAT proteomic analysis of mRNA translation during metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5641c783a1f4cb045291261a2bfe4c
https://doi.org/10.1158/1078-0432.22468893
https://doi.org/10.1158/1078-0432.22468893
Autor:
Chand Khanna, Peter C. Scacheri, Timothy M. Fan, Ming Zhou, Daniel L. Gustafson, Ryan J. Hansen, Timothy J. Waybright, Ling Ren, Michael M. Lizardo, Allyson Koyen, Arnulfo Mendoza, James J. Morrow
Highly metastatic osteosarcoma cells activate the mTOR pathway during metastatic progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9dfd5d9a8e75dd89d47a80b6f9924e
https://doi.org/10.1158/1078-0432.22468896
https://doi.org/10.1158/1078-0432.22468896