Aczonin, a 550-Kd Putative Scaffolding Protein of Presynaptic Active Zones, Shares Homology Regions with Rim and Bassoon and Binds Profilin

Autor: Xiaolu Wang, Mark Kibschull, Beate Lichte, Manfred W. Kilimann, Michael M. Laue, Elisabeth Petrasch-Parwez

Publikováno v: The Journal of Cell Biology

Neurotransmitter exocytosis is restricted to the active zone, a specialized area of the presynaptic plasma membrane. We report the identification and initial characterization of aczonin, a neuron-specific 550-kD protein concentrated at the presynapti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c301c383aab3a02c1e037b3658f8911b
https://doi.org/10.1083/jcb.147.1.151

Neurobeachin: A Protein Kinase A-Anchoring,beige/Chediak-Higashi Protein Homolog Implicated in Neuronal Membrane Traffic

Autor: Elisabeth Petrasch-Parwez, Bin Hu, Michael M. Laue, Xiaolu Wang, Friedrich W. Herberg, Christiane Wüllner, Manfred W. Kilimann

We describe the identification and initial characterization of neurobeachin, a neuron-specific multidomain protein of 327 kDa with a high-affinity binding site (Kd, 10 nm) for the type II regulatory subunit of protein kinase A (PKA RII). Neurobeachin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36f978d5263c2c38bdd38389519dca1
https://europepmc.org/articles/PMC6773050/

Diagnostic electron microscopy in human infectious diseases - Methods and applications.

Autor: Laue M; Centre for Biological Threats and Special Pathogens (ZBS 4), Advanced Light and Electron Microscopy, Robert Koch Institute, Berlin, Germany.

Publikováno v: Journal of microscopy [J Microsc] 2024 Nov 19. Date of Electronic Publication: 2024 Nov 19.

LRBA, a BEACH protein mutated in human immune deficiency, is widely expressed in epithelia, exocrine and endocrine glands, and neurons.

Autor: Roussa E; Department Molecular Embryology, Institute of Anatomy and Cell Biology, Faculty of Medicine, Albert-Ludwigs-University Freiburg, Freiburg, Germany., Juda P; Department of Molecular Neurobiology, Max-Planck-Institute for Multidisciplinary Sciences, Göttingen, Germany.; Leukocyte Motility Lab, 1st Faculty of Medicine, Charles University of Prague, Vestec, Czech Republic., Laue M; Advanced Light and Electron Microscopy (ZBS 4), Robert Koch Institute, Berlin, Germany., Mai-Kolerus O; Department of Molecular Genetics, German Institute for Human Nutrition, Potsdam-Rehbruecke, Germany.; Einstein Center for Neurosciences, Charite - Universitätsmedizin Berlin, Berlin, Germany., Meyerhof W; Department of Molecular Genetics, German Institute for Human Nutrition, Potsdam-Rehbruecke, Germany.; Center for Integrative Physiology and Molecular Medicine, Saarland University, Homburg, Germany., Sjöblom M; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden., Nikolovska K; Department of Gastroenterology, Hepatology, Infectiology and Endocrinology, Medical University Hannover, Hannover, Germany., Seidler U; Department of Gastroenterology, Hepatology, Infectiology and Endocrinology, Medical University Hannover, Hannover, Germany., Kilimann MW; Department of Molecular Neurobiology, Max-Planck-Institute for Multidisciplinary Sciences, Göttingen, Germany. kilimann@mpinat.mpg.de.

Publikováno v: Scientific reports [Sci Rep] 2024 May 09; Vol. 14 (1), pp. 10678. Date of Electronic Publication: 2024 May 09.

A recent gibbon ape leukemia virus germline integration in a rodent from New Guinea.

Autor: Mottaghinia S; Department of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, Berlin 10315, Germany.; Centre International de Recherche en Infectiologie, Université de Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, École Nationale Supérieure de Lyon, Lyon F-69007, France., Stenzel S; Institute of Virology Charité-Universitätsmedizin Berlin, Berlin D-10117, Germany.; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom., Tsangaras K; Department of Life and Health Sciences, University of Nicosia, Nicosia CY-2417, Cyprus., Nikolaidis N; Department of Biological Science, Center for Applied Biotechnology Studies, and Center for Computational and Applied Mathematics, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, CA 92834-6850., Laue M; Advanced Light and Electron Microscopy (ZBS 4), Centre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin D-13353, Germany., Müller K; Department of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, Berlin 10315, Germany., Hölscher H; Department of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, Berlin 10315, Germany., Löber U; Max-Delbrük Center for Molecular Medicine Helmholtz Association, Berlin 13125, Germany., McEwen GK; Department of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, Berlin 10315, Germany., Donnellan SC; South Australian Museum, North Terrace, Adelaide SA 5000, Australia., Rowe KC; Sciences Department, Museums Victoria, Melbourne, VIC 3001, Australia., Aplin KP; South Australian Museum, North Terrace, Adelaide SA 5000, Australia., Goffinet C; Institute of Virology Charité-Universitätsmedizin Berlin, Berlin D-10117, Germany.; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom., Greenwood AD; Department of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, Berlin 10315, Germany.; School of Veterinary Medicine, Freie Universität Berlin, Berlin 14163, Germany.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Feb 06; Vol. 121 (6), pp. e2220392121. Date of Electronic Publication: 2024 Feb 01.