Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Michael M. Halassa"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Cognitive flexibility is a fundamental ability that enables humans and animals to exhibit appropriate behaviors in various contexts. The thalamocortical interactions between the prefrontal cortex (PFC) and the mediodorsal thalamus (MD) have
Externí odkaz:
https://doaj.org/article/f87593b327e34d0fbc0de58a3df0d1fc
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Humans and other animals can maintain constant payoffs in an uncertain environment by steadily re-evaluating and flexibly adjusting current strategy, which largely depends on the interactions between the prefrontal cortex (PFC) and mediodorsal thalam
Externí odkaz:
https://doaj.org/article/7fe868309e124eebb74f2d9fb37e2903
Autor:
Alan Anticevic, Michael M. Halassa
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Psychosis spectrum disorder (PSD) affects 1% of the world population and results in a lifetime of chronic disability, causing devastating personal and economic consequences. Developing new treatments for PSD remains a challenge, particularly those th
Externí odkaz:
https://doaj.org/article/5b80e2d2125445d79167eaaa03639db5
Autor:
Mien Brabeeba Wang, Michael M. Halassa
Publikováno v:
Network Neuroscience, Vol 6, Iss 4, Pp 980-997 (2022)
AbstractAnimal brains evolved to optimize behavior in dynamic environments, flexibly selecting actions that maximize future rewards in different contexts. A large body of experimental work indicates that such optimization changes the wiring of neural
Externí odkaz:
https://doaj.org/article/b1cf1b35c78b45c79b919cf62466e64c
Publikováno v:
Computational Psychiatry, Vol 2, Pp 141-163 (2018)
In many studies of attention-deficit hyperactivity disorder (ADHD), stimulus encoding and processing (perceptual function) and response selection (executive function) have been intertwined. To dissociate deficits in these functions, we introduced a t
Externí odkaz:
https://doaj.org/article/72126f12174747e597904849a43c02fe
Autor:
Michael M. Halassa, Marco Dal Maschio, Riccardo Beltramo, Philip G. Haydon, Fabio Benfenati, Tommaso Fellin
Publikováno v:
The Scientific World Journal, Vol 10, Pp 1634-1645 (2010)
Although astrocytes are increasingly recognized as important modulators of neuronal excitability and information transfer at the synapse, whether these cells regulate neuronal network activity has only recently started to be investigated. In this art
Externí odkaz:
https://doaj.org/article/ca6161589a9b43ae9ac98e954c7a05e9
Publikováno v:
Nat Neurosci
The thalamus engages in various functions including sensory processing, attention, decision making and memory. Classically, this diversity of function has been attributed to the nuclear organization of the thalamus, with each nucleus performing a wel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376fa3cdb8339d5eaf22404ffb9b7fa4
https://doi.org/10.1038/s41593-021-00996-1
https://doi.org/10.1038/s41593-021-00996-1
The mediodorsal (MD) thalamus is a critical partner for the prefrontal cortex (PFC) in cognitive flexibility. Animal experiments have shown that the MD enhances prefrontal signal-to-noise ratio (SNR) in decision making under uncertainty. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b09850e7a46e42bbc537c4b799ee6ff4
https://doi.org/10.1101/2022.12.11.519975
https://doi.org/10.1101/2022.12.11.519975
Publikováno v:
Nature
Interactions between the mediodorsal thalamus and the prefrontal cortex are critical for cognition. Studies in humans indicate that these interactions may resolve uncertainty in decision-making1, but the precise mechanisms are unknown. Here we identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551951dc426eea2784826ce51a29d8be
https://doi.org/10.1038/s41586-021-04056-3
https://doi.org/10.1038/s41586-021-04056-3
Publikováno v:
Cognitive Computation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f0b4b1dbc0ee2c48ae06248c2aa773e
https://doi.org/10.1007/s12559-022-09994-2
https://doi.org/10.1007/s12559-022-09994-2