Výsledky vyhledávání - "Michael M Lizardo"

Akademický článek

Imaging the impact of chemically inducible proteins on cellular dynamics in vivo.

Autor: Hon S Leong, Michael M Lizardo, Amber Ablack, Victor A McPherson, Thomas J Wandless, Ann F Chambers, John D Lewis

Publikováno v: PLoS ONE, Vol 7, Iss 1, p e30177 (2012)

The analysis of dynamic events in the tumor microenvironment during cancer progression is limited by the complexity of current in vivo imaging models. This is coupled with an inability to rapidly modulate and visualize protein activity in real time a

Externí odkaz: https://doaj.org/article/698170a09f0149ccac385d7cc8d5339f

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Akademický článek

Nitric oxide synthase and breast cancer: role of TIMP-1 in NO-mediated Akt activation.

Autor: Lisa A Ridnour, Kimberly M Barasch, Alisha N Windhausen, Tiffany H Dorsey, Michael M Lizardo, Harris G Yfantis, Dong H Lee, Christopher H Switzer, Robert Y S Cheng, Julie L Heinecke, Ernst Brueggemann, Harry B Hines, Chand Khanna, Sharon A Glynn, Stefan Ambs, David A Wink

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e44081 (2012)

Prediction of therapeutic response and cancer patient survival can be improved by the identification of molecular markers including tumor Akt status. A direct correlation between NOS2 expression and elevated Akt phosphorylation status has been observ

Externí odkaz: https://doaj.org/article/5a65063fd7054d7e9e1b11657caa0e77

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Akademický článek

NSG Mice Facilitate ex vivo Characterization of Ewing Sarcoma Lung Metastasis Using the PuMA Model

Autor: Renata Scopim-Ribeiro, Michael M. Lizardo, Hai-Feng Zhang, Anne-Chloé Dhez, Chistopher S. Hughes, Poul H. Sorensen

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

Ewing sarcoma (EwS) is a highly malignant bone and soft tissue tumor primarily affecting children and young adults. While most patients initially respond well to conventional front-line therapy, frequent metastasis results in poor 5-year overall surv

Externí odkaz: https://doaj.org/article/07b9de9743a241a6915fee7b0ab6f226

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Akademický článek

Understanding and Modeling Metastasis Biology to Improve Therapeutic Strategies for Combating Osteosarcoma Progression

Autor: Timothy M. Fan, Ryan D. Roberts, Michael M. Lizardo

Publikováno v: Frontiers in Oncology, Vol 10 (2020)

Osteosarcoma is a malignant primary tumor of bone, arising from transformed progenitor cells with osteoblastic differentiation and osteoid production. While categorized as a rare tumor, most patients diagnosed with osteosarcoma are adolescents in the

Externí odkaz: https://doaj.org/article/b6f1a0df81d247859fdae0aceac0e9a5

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