Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Michael M C. Lai"'
Autor:
Chia-Lin Chen, Jeffrey Y. Huang, Chun-Hsiang Wang, Stanley M Tahara, Lin Zhou, Yasuteru Kondo, Joel Schechter, Lishan Su, Michael M C. Lai, Takaji Wakita, François-Loïc Cosset, Jae U Jung, Keigo Machida
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Infection of B cells by hepatitis C virus (HCV) is poorly understood, but is thought to result in lymphoproliferative disorders. Here, Chenet al. identify CD86 as co-receptor for lymphotropic HCV and show that HCV infection inhibits memory B-cell fun
Externí odkaz:
https://doaj.org/article/1991ac8957f64473b697653d17ea07e4
Autor:
Mei-Lin Yang, Yi-Cheng Chen, Chung-Teng Wang, Hao-Earn Chong, Nai-Hui Chung, Chia-Hsing Leu, Fu-Tong Liu, Michael M. C. Lai, Pin Ling, Chao-Liang Wu, Ai-Li Shiau
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-22 (2023)
Abstract Background Influenza is one of the most important viral infections globally. Viral RNA-dependent RNA polymerase (RdRp) consists of the PA, PB1, and PB2 subunits, and the amino acid residues of each subunit are highly conserved among influenz
Externí odkaz:
https://doaj.org/article/8201530a06c646baba7c06ffdd648f2d
Autor:
Ivonne Melano, Wei-Chung Cheng, Li-Lan Kuo, Yuag-Meng Liu, Yu Chi Chou, Mien-Chie Hung, Michael M. C. Lai, Yuh-Pyng Sher, Wen-Chi Su
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of the Coronavirus disease-19 (COVID-19) pandemic, utilizes angiotensin-converting enzyme 2 (ACE2) as a receptor for virus infection. However, the expression
Externí odkaz:
https://doaj.org/article/019f88b4e76647a19ada77ea39f4d35e
Autor:
Hsin-I Wang, Zih-Shiuan Chuang, Yu-Ting Kao, Yi-Ling Lin, Jian-Jong Liang, Chun-Che Liao, Ching-Len Liao, Michael M. C. Lai, Chia-Yi Yu
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 9087 (2021)
The SARS-CoV-2 pseudovirus is a commonly used strategy that mimics certain biological functions of the authentic virus by relying on biological legitimacy at the molecular level. Despite the fact that spike (S), envelope (E), and membrane (M) protein
Externí odkaz:
https://doaj.org/article/a3dd9a4df3fb4e8c8ffeb1ddb7508ba6
Autor:
Chia-Yin Ho, Wen-Chi Su, Yi-Chun Chen, Meng-Yen Ho, Wen-Ya Yu, Michael M. C. Lai, Yuag-Meng Liu, Hui-Chen Chen
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases
Emerging evidence highlights the role of non-coding small RNAs in host-influenza interaction. We have identified a Y RNA-derived small RNA, miR-1975, which is upregulated upon influenza A virus infection in A549 cells. The aim of this study is to inv
Autor:
Chung-Hsin Tseng, Michael M. C. Lai
Publikováno v:
Viruses, Vol 1, Iss 3, Pp 818-831 (2009)
Hepatitis delta virus (HDV) is a distant relative of plant viroids in the animal world. Similar to plant viroids, HDV replicates its circular RNA genome using a double rolling-circle mechanism. Nevertheless, the production of hepatitis delta antigen
Externí odkaz:
https://doaj.org/article/e3b78d961c624134a0cc86da0aadaed8
Autor:
Yu-Ting Kao, Michael M. C. Lai, Zih-Shiuan Chuang, Chia-Yi Yu, Yi-Ling Lin, Chun-Che Liao, Jian-Jong Liang, Ching-Len Liao, Hsin-I Wang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9087, p 9087 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences
Volume 22
Issue 16
The SARS-CoV-2 pseudovirus is a commonly used strategy that mimics certain biological functions of the authentic virus by relying on biological legitimacy at the molecular level. Despite the fact that spike (S), envelope (E), and membrane (M) protein
Autor:
Yasuteru Kondo, Masashi Ninomiya, Osamu Kimura, Keigo Machida, Ryo Funayama, Takeshi Nagashima, Koju Kobayashi, Eiji Kakazu, Takanobu Kato, Keiko Nakayama, Michael M C Lai, Tooru Shimosegawa
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98521 (2014)
Various kinds of autoimmune diseases have been reported to have a significant relationship with persistent hepatitis c virus (HCV) infection and Th17 cells. Previously, our group reported that the existence of HCV in T lymphocytes could affect the de
Externí odkaz:
https://doaj.org/article/53c400fd0106417283a5f2c61a01d42c
Autor:
Yung-Ju Yeh, His-Yuan Huang, Hsien Da Huang, Sheng Da Hsu, Ju-Chien Cheng, Michael M. C. Lai, Ching-Ping Tseng
Publikováno v:
J Virol
MicroRNA let-7b expression is induced by infection of hepatitis C virus (HCV) and is involved in the regulation of HCV replication by directly targeting the HCV genome. The current study demonstrated that let-7b directly targets negative regulators o
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002766 (2012)
For Hepatitis C virus (HCV), initiation of translation is cap-independently mediated by its internal ribosome entry site (IRES). Unlike other IRES-containing viruses that shut off host cap-dependent translation, translation of HCV coexists with that
Externí odkaz:
https://doaj.org/article/36f9ad27b6f14032ad4c6c7f57925acc