Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael Lytinas"'
Autor:
Nikoletta Papadopoulou, Donelan J, Michael Lytinas, William Boucher, Dean Papaliodis, Paul R. Dobner, Theoharis C. Theoharides
Publikováno v:
Proceedings of the National Academy of Sciences. 103:7759-7764
Many skin disorders are associated with increased numbers of activated mast cells and are worsened by stress; however, the mechanism underlying these processes is not understood. Corticotropin-releasing hormone (CRH) is secreted under stress from the
Autor:
Man Huang, Spyridon Christodoulou, Nikoletta Papadopoulou, Kristiana Kandere-Grzybowska, Achilles Athanassiou, B. Madhappan, Duraisamy Kempuraj, Michael Lytinas, William Boucher, Theoharis C. Theoharides
Publikováno v:
Endocrinology. 145:43-48
Stress activates the hypothalamic-pituitary-adrenal axis through CRH, leading to production of glucocorticoids that down-regulate immune responses. However, acute stress also has proinflammatory effects. We previously showed that restraint stress, as
Autor:
Theoharis C. Theoharides, Duraisamy Kempuraj, Man Huang, Pamela Esposito, William Boucher, Michael Lytinas
Publikováno v:
International archives of allergy and immunology. 130(3)
Background: Mast cells play an important role in allergic inflammation by releasing vasoactive molecules, proteases and cytokines. Corticotropin-releasing hormone (CRH) and its structural analogue urocortin (Ucn) were shown to trigger skin mast cell
Autor:
Michael, Lytinas, Duraisamy, Kempuraj, Man, Huang, Kristiana, Kandere, William, Boucher, Richard, Letourneau, Sheila, Jeudy, Kim, Fitzgerald, Kathleen, Spear, Achilles, Athanasiou, Theoharis C, Theoharides
Publikováno v:
Allergy and asthma proceedings. 23(1)
Mast cells are involved in early and late-phase reactions by releasing vasoactive molecules, proteases, and cytokines. Azelastine and olopatadine are histamine 1 receptor (H-1R) antagonists with antiallergic effects present in the ophthalmic solution